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Pharmaceutical Intermediates Meaning

Intermediates are a very important type of fine chemical products. In essence, they are a kind of “semi-finished products”, which are intermediate products in the production of certain products. It is widely used in the synthesis of medicines, pesticides, coatings, dyes and perfumes. In the pharmaceutical field, intermediates are an important link in the industrial chain of the pharmaceutical industry. They are used for some chemical raw materials or chemical products in the process of drug synthesis. Pharmaceutical intermediates are used in the production process from pharmaceutical chemical raw materials to APIs or drugs. A fine chemical product, the synthesis of chemical drugs relies on high-quality pharmaceutical intermediates.

Types of Pharmaceutical Intermediates

There are many types of pharma intermediates, which can be divided into antibiotics intermediates, antipyretic and analgesic intermediates, cardiovascular system pharmaceutical intermediates, and anti-cancer pharmaceutical intermediates according to application fields. There are many types of specific pharmaceutical intermediate products, such as imidazole, furan, phenol intermediates, aromatic intermediates, pyrrole, pyridine, biochemical reagents, sulfur-containing, nitrogen-containing, halogen compounds, heterocyclic compounds, starch, mannitol , Microcrystalline cellulose, lactose, dextrin, glycols, powdered sugar, inorganic salts, ethanol intermediates, stearates, amino acids, ethanolamines, potassium salts, sodium salts and other intermediates, etc.

pharmaceutical intermediates

Common pharmaceutical intermediates

Methoxybenzoic acid (Methoxybenzoic acid), also known as p-anisic acid, 4-anisic acid, anisic acid, is a colorless needle-like crystal at room temperature, soluble in ethanol, ether, chloroform, slightly soluble in hot water, insoluble In cold water. The intermediate p-methoxybenzoyl chloride of amiodarone was prepared by thionyl chloride chlorination. It can be used as a pharmaceutical intermediate of Galracetam, as well as spices and preservatives.

Crystalline high tin chloride, also called crystalline tin tetrachloride, tin chloride, tin tetrachloride, chemical formula SnCl4, formula weight 260.53. Colorless fuming liquid, acidic. It is soluble in water and emits a lot of heat. Its dilute aqueous solution produces stannic acid precipitation due to hydrolysis. It can be freely miscible with alcohol, carbon disulfide and turpentine. The absorption capacity of chlorine gas is very large.

4-Cyanopyridine is a white to light yellow needle-like crystal with a characteristic odor. Its main purpose is to be used as a pharmaceutical and pesticide intermediate.

Caprolactam is an important organic raw material that can be used to make polycaprolactam resin, polycaprolactam fiber, artificial leather, plastics, engineering plastics, polymer solvents, coatings, plasticizers, pharmaceutical raw materials, synthetic lysine raw materials, etc. .
Uses: used as intermediates for medicines, dye intermediates, food additives, feed additives, pesticides, etc.

Caprolactam is an important organic raw material that can be used to make polycaprolactam resin, polycaprolactam fiber, artificial leather, plastics, engineering plastics, polymer solvents, coatings, plasticizers, pharmaceutical raw materials, synthetic lysine raw materials, etc. .
Uses: Cyclohexanone oxime is used as a cathode inhibitor to inhibit the corrosion of aluminum in hydrochloric acid.

Uses: Intermediate of Atovaquone

Uses: Daily chemical bacteriostatic agent. It has the characteristics of continuous, safe and stable sterilization, has excellent compatibility with the skin, and has a highly effective anti-bacterial effect on gram-positive bacteria, gram-negative bacteria, fungi, yeasts, and viruses.

Sodium monofluorophosphate (“MFP” for short) is a white powdery solid with a melting point of about 626°C. It is easily soluble in water and has strong hygroscopicity. The solubility in water at 25°C is 42%. There is no rust effect. The pH of the 2% aqueous solution is 6.5 to 8.0. The aqueous solution undergoes slow hydrolysis when boiling, which can lead to a decrease in bound fluorine and an increase in free fluorine, so the purity is reduced.
Application: Sodium monofluorophosphate has a wide range of applications, mainly used in toothpaste additives, concrete corrosion inhibitors, food, medical treatment, etc.

As a special engineering material, polyimide has the advantages of high temperature resistance, radiation resistance and high mechanical strength. It is used in films, coatings, fibers, aerospace, electronic and electrical industries, foam plastics, and photoresists.
Use spices. Dye intermediates. Resin synthesis.