Xylazine Hydrochloride CAS 23076-35-9

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  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Xylazine Hydrochloride Supplier&Manufacturer

Basic Info of Xylazine Hydrochloride

What is Xylazine Hydrochloride?

Xylazine hydrochloride is the hydrochloride of xylazine. It is made use of in veterinary medication as a sedative, analgesic and muscle mass depressant. It works as an alpha-adrenergic agonist, analgesic, emetic, muscle relaxant as well as sedative. It has xylazine (1+).

Xylazine hydrochloride, also known as xylazine hydrochloride, is a sedative vet drug. It can make the central nerves produce mild inhibition as well as deteriorate useful tasks, therefore getting rid of restlessness and also restoring serenity. In recent times, driven by economic passions, individual animals breeders arbitrarily included such medicines in the process of animals and fowl breeding to play the role of sedation as well as hypnotherapy, weight gain as well as fattening, as well as shortening the time of slaughtering; Decrease pet death and fat burning, avoid meat quality loss, as well as are usually utilized to lower stress-induced losses.

Xylazine Hydrochloride Uses

  1. Xylazine is very similar to phenothiazine, tricyclic antidepressants and clonidine. As an anesthetic, it is usually used with ketamine.
  2. Xylazine HCl is a α Adrenergic receptor agonists, usually used as sedatives, muscle relaxants, and analgesics. It is often used to treat tetanus.
  3. Xylazine seems to reduce the sensitivity of the human body to insulin and glucose intake. Yohimbine is a α Adrenaline receptor antagonists have been used to reduce glucose levels to healthy levels. In the clinical environment, yohimbine can reverse the side effects of methylthiazide if administered intravenously shortly after its administration.
  4. Xylazine Hydrochloride, also called mexothiazide hydrochloride, is a type of sedative vet medication. It can make the central nerves generate small restraint, compromise useful tasks, and also thus play a class of medications to get rid of restlessness and also restore silent.
  5. In animals, methylthiazide can be administered intramuscularly or intravenously. As a veterinary anesthetic, methylthiazide is usually used only once before or during surgery to achieve the desired effect.

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Application of Xylazine Hydrochloride

Yu Qing et al. analyzed the effects of ketamine and xylazine hydrochloride, the free base of xylazine, on anesthesia in a rat model of spinal cord injury. Methods Sixty Sprague-Dawley male rats were treated with ketamine hydrochloride 100 mg/kg (group I), xylazine hydrochloride 25 mg/kg (group II), ketamine hydrochloride 100 mg/kg compound xylazine hydrochloride 25 mg/kg After intraperitoneal injection of anesthesia (group Ⅲ), an animal model of spinal cord injury was established. Non-invasive ECG monitors were used to monitor changes in heart rate, respiration, blood oxygen saturation and body temperature. Pain and muscle relaxation.

Results The onset time of anesthesia in group III was (2.2±0.5) min, which was significantly shorter than (14.3±2.3) min in group I and (18.2±3.0) min in group II (both P<0.05). The duration of anesthesia in group III was (139.0±12.6) min, which was significantly longer than (41.6±6.2) min in group I and (63.9±8.2) min in group II (both P<0.01). The heart rate, respiration, blood oxygen saturation and body temperature of group III remained stable at each time point during anesthesia. Conclusion The intraperitoneal injection of ketamine hydrochloride 100 mg/kg combined with xylazine hydrochloride 25 mg/kg is more effective than ketamine hydrochloride or xylazine hydrochloride alone for anesthesia in the rat model of spinal cord injury.

Xylazine Metabolites

Xylazine-M (2,6 dimethylaniline)

Xylazine-M (N-thiourea-2,6-dimethylaniline)

Xylazine-M (sulfone-HO-) isomer 2

Xylazine-M (HO-2,6-dimethylaniline isomer 1)

Xylazine-M (HO-2,6-dimethylaniline isomer 2)

Xylazine M (oxo-)

Xylazine-M (HO-) isomer 1

Xylazine-M (HO-) isomer 1 glucuronide

Xylazine-M (HO-) isomer 2

Xylazine-M (HO-) isomer 2 glucuronide

Xylazine-M (HO-oxo-) isomer 1

Xylazine-M (HO-oxo-) isomer 1 glucuronide

Xylazine-M (HO-oxo-) isomer 2

Xylazine-M (HO-oxo-) isomer 2 glucuronide

Xylazine-M (sulfone)

 

Xylazine-M (sulfone-HO-) isomer 1

 

Reference

  1. Xylazine – WikiPedia
  2. Xylazine hydrochloride – PubChem
  3. Yu Qing,Gu Ying,Chen Tongyi.Anesthesia effect of ketamine and xylazine on spinal cord injury model in rats[J].Shanghai Medical Science,2011,34(08):594-597.

Xylazine Hydrochloride Suppliers and Manufacturers

As a xylazine hydrochloride supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best xylazine hydrochloride raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have demand for xylazine hydrochloride and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.

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