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Vitamin B12 Cobalamin CAS 68-19-9

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  • Appearance: Red powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Vitamin B12 Cobalamin Supplier & Manufacturer

Basic Info of Vitamin B12 Cobalamin

What is Vitamin B12 Cobalamin?

Cyanocobalamin (cbl), also known as vitamin B12, is a class of water-soluble compounds containing cobalt. Different forms of cobalt have been discovered since the 1960s. The first one was cyanocobalamin, followed by methylcobalt. Amine, Hydroxocobalamin and Adenosylcobalamin, among which Hydroxocobalamin belongs to the natural form of Cyanocobalamin and exists in food, and the other three forms need to be industrially synthesized. As an important cofactor in the body, cyanocobalamin plays a key role in the methionine (methionine) cycle of homocysteine ​​metabolism and the isomerization of methylmalonic acid-succinic acid. Oxidative stress, intracellular signal transduction, apoptosis and other processes.

Cyanocobalamin in nature is synthesized by microbes. Higher animals and plants can not manufacture cyanocobalamin by themselves. Consequently, the human body needs to ingest it via animal food, including milk, eggs, fish and meat. The American Institute of Medicine suggests that the intake of cyanocobalamin is 2.4 μg/ d, as well as the Chinese Nutrition Association advises 1.0-3.2 μg/ d.

Generally, vitamin B12 can promote the growth as well as maturation of red cell, maintain the body’s hematopoietic feature in a regular state, protect against pernicious anemia, maintain the wellness of the nerve system, and also promote protein synthesis. Jaclyn London, MS, RD, CDN, Supervisor of Nourishment at The Good Home cleaning Institute, claimed: “As you age, getting B12 daily is critical as a shortage can lead to cognitive decline and also impaired neurological feature. Vitamin B12 is necessary in the human body. In biochemical responses, it is associated with DNA synthesis, change of damaging substances, and so on, and also is closely related to the maturation of blood cells, preserving the wellness of blood vessels as well as nervous system. Lack of B12 might result in neurological signs and symptoms such as megaloblastic anemia, vascular sclerosis and depression.

Vitamin B12 Cobalamin Uses

Vitamin B12 plays a very crucial role in several functions of the body, consisting of: DNA synthesis, energy manufacturing, keeping the wellness of afferent neuron, red cell development, nervous system feature. B12 is found in lots of foods and is bound in the healthy protein particles of the food.

Some common indications of vitamin B12 shortage include: lowered cognitive function, such as troubles with memory or understanding, tiredness, sleepiness, bowel irregularity, vague feelings, clinical depression or irritation, frustration, problem maintaining equilibrium, sore tongue, mouth sores, really feel numb,

Visual modifications. Risk factors for vitamin B12 shortage are also related to insulin levels, so some medications for type 2 diabetes mellitus can raise the danger of vitamin B12 shortage. In addition, the complying with threat aspects can additionally enhance the chance of vitamin B12 shortage: alcoholic abuse, cigarette smoking, taking specific prescription medications, consisting of antacids and also some type 2 diabetes medicines, having an autoimmune condition such as diabetes or thyroid disease, pure vegan diet regimen, certain food poisonings such as Crohn’s disease, gastric bypass surgery or removal of part of the belly, aging, have stomach problems, this is because an irregular gastrointestinal tract may prevent vitamin B12 release or take in.

Vitamin B12 injections, which do not damage the intestinal tract, can likewise lower the danger of vitamin B12 deficiency and also relevant issues. Complications of extreme vitamin B12 shortage include: cardiovascular disease, neurocognitive problems, sychronisation troubles, outer neuropathy, vision loss, the inability to conceive, and also much more.

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Application of Vitamin B12 Cobalamin

  • Medical as well as medical care applications
    It is generally utilized to deal with different VB12 deficiency, such as: megaloblastic anemia, anemia triggered by medication poisoning, aplastic anemia and leukopenia, and so on; made use of in combination with pantothenic acid, it can stop destructive anemia and help Absorption of Fe2+ and also secretion of stomach acid; likewise utilized to deal with joint inflammation, facial nerve palsy, trigeminal neuralgia, liver disease, herpes, bronchial asthma and also various other allergies, atopic dermatitis, hives, dermatitis and also bursitis; VB12 can also For the therapy of anxiety, irritation, sleeplessness, memory loss, and anxiety. New research study suggests that VB12 deficiency additionally adds to mental disorders such as clinical depression. VB12 is very risk-free as a healing representative or health care product, and also no poisoning phenomenon was found by intravenous or intramuscular injection of VB12 that was several thousand times greater than RDA.

  • Application in feed
    VB12 can promote the development as well as growth of fowl and also animals, especially young birds and also young animals, and also enhance the use rate of feed healthy protein, so it can be utilized as a feed additive. Dealing with fish eggs or fry with VB12 aqueous solution can enhance the tolerance of fish to poisonous substances in water such as benzene and also heavy metals, as well as decrease mortality. Considering that the “Mad Cow Illness” incident in Europe, using dietary supplements with clear chemical structures such as vitamins to replace “meat and also bone dish” has even more room for advancement. The majority of the VB12 generated worldwide is presently used in the feed market.
  • Application in other aspects
    In industrialized countries, VB12 and other substances are made use of in cosmetics; in the food market, VB12 can be utilized as a colorant for pork, sausage, gelato, fish sauce and other foods. In domesticity, VB12 remedy is adsorbed on turned on carbon, zeolite, non-woven fiber or paper, or made right into soap, toothpaste, etc; it can be utilized for deodorization of commodes, refrigerators, and so on, and also eliminate the odor of sulfide and also aldehyde; VB12 can also be used Dehalogenation of natural halides, typical contaminants in soil as well as surface area water in environmental protection.

Causes and Diseases of Vitamin B12 Cobalamin Deficiency

Reference

  1. Vitamin B12 – WikiPedia
  2. Cyanocobalamin – PubChem

Vitamin B12 Cobalamin Supplier and Manufacturer

As a vitamin b12 cobalamin supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best vitamin b12 cobalamin raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for vitamin b12 cobalamin and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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