Trichloroacetyl chloride CAS 76-02-8

Factory Supply Trichloroacetyl chloride CAS 76-02-8 with Best Price

  • Appearance: Colorless liquid 
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Trichloroacetyl Chloride Supplier & Manufacturer

Basic Info of Trichloroacetyl chloride

What is Trichloroacetyl chloride?

Trichloroacetyl chloride is the acyl chloride of trichloroacetic acid. It can be formed by the reaction of chlorine with acetyl chloride or acetaldehyde in the presence of activated carbon. It can be used to manufacture drugs and plant pesticides.

It can be obtained by reacting acetyl chloride or acetaldehyde with chlorine in the presence of activated carbon. Trichloroacetyl chloride is also produced by the reaction of oxygen and tetrachloroethylene in the presence of ultraviolet light and catalyst.

Nitric acid reacts with Trichloroacetaldehyde to obtain trichloroacetic acid, and then phosphorus trichloride is added to trichloroacetic acid for reaction. After the reaction, the product is separated to obtain trichloroacetyl chloride.

Trichloroacetyl chloride Uses

  1. Trichloroacetyl chloride can be used to synthesize pesticides, herbicides, fungicides, etc.
  2. Trichloroacetyl chloride is used as an important raw material for organic synthesis, an important intermediate for pesticides chlorpyrifos, methyl chlorpyrifos and herbicides
  3. Trichloroacetyl chloride is widely used in the synthesis of broad-spectrum, high-efficiency insecticides, acaricides chlorpyrifos, chlorpyrifos methyl and important intermediates for herbicides.
  4. Acetylation of esters.

If you want to buy trichloroacetyl chloride, pls contact us to get a free quote.

The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

Contact Us


Phone: +86 176-5311 3209

WhatsApp: +86 176-5311 3209

Application of Trichloroacetyl chloride

My country is a big country in the production and use of pesticides. Although the project to eliminate high-toxicity and high-residue pesticides has been started, some low-cost, high-toxicity, and high-residue pesticides are still used under the drive of interests. The poisoning of edible fruits and vegetables has been reported frequently, and it is a serious threat. people’s health. Both chlorpyrifos and chlorpyrifos methyl are a new generation of alternative pesticide products. Their superior broad-spectrum, high-efficiency, low-toxicity, and low-residue characteristics have made them popular and applied all over the world.

“Chlorpyrifos”, also known as “Lesben”, is the only organophosphorus product licensed by the International Health Organization. No matter in the international or domestic market, “chlorpyrifos” has a large market capacity. Chlorpyrifos can control more than 100 kinds of pests. It has contact killing, stomach poisoning and fumigation effects, and can be used for the control of agricultural, animal husbandry and sanitary pests.

Add trichloroacetyl chloride and acrylonitrile in a mass ratio of 1.0:0.9~1.0:1.3 into a four-necked flask equipped with a stirrer, a thermometer and a reflux condenser, heat at 120~140 °C, and put Add 1:1 copper powder and cuprous chloride catalyst under stirring, react under nitrogen protection for 8-16 h, the mass ratio of the total amount of catalyst to trichloroacetyl chloride is about 0.1:1.0, and the solvent is nitrobenzene , dichlorobenzene or xylene. A brown mixture was obtained, the solid catalyst was removed by filtration, and a pale yellow transparent liquid (addition product) was obtained.

The unreacted raw materials and solvent were evaporated under reduced pressure, and then transferred to a three-necked flask with a stirrer, a gas introduction tube and a reflux condensing device, and dry hydrogen chloride gas was introduced at 30-50 °C, and stirred for 3-10 h. The hydrogen chloride in the solution was removed under reduced pressure to obtain the cyclized product pyridone. Slowly add sodium hydroxide solution dropwise, a large amount of pale yellow solids will be produced, continue to stir, and control the temperature at room temperature, stir for 5-10 h, filter and dry to obtain sodium picolinate. After acidification with hydrochloric acid or sulfuric acid, a large amount of light yellow powder can be obtained, and after standing for a period of time, pyridine phenol crystals are precipitated. The yield is about 65%. Some people adopt this synthetic route, but its experimental method is relatively simple, and has the characteristics of short technological process, easy operation and high yield.

4′-Hydroxybiphenyl-4-carbonitrile can be used as a liquid catalyst and an intermediate for antithrombotic drugs. In the presence of AlCl 3 , 4-hydroxybiphenyl can undergo a high yield and high regioselectivity acetylation reaction with trichloroacetyl chloride to obtain 4-(trichloroacetyl)-4′-hydroxybiphenyl, It is then reacted with ammonia to be converted into the corresponding formamide, and the formamide is dehydrated with a dehydrating agent to obtain 4′-hydroxybiphenyl-4-carbonitrile.

Using metal halide as an exchange medium, benzothiazole and trichloroacetyl chloride can react to obtain 2-chlorobenzothiazole in high yield. If ethyl trichloroacetate is added during the reaction, the yield can be improved.

Combining trichloroacetyl chloride and organozinc intermediate, then in DMF, phenylacrolein was treated with trichloroacetic acid and sodium trifluoroacetate to obtain 4-phenyl-1,1,1-tris with a mass fraction of 97% Chloro-2-butanone.

Using acetone as a solvent, in the presence of sodium bicarbonate, 2-(4-bromoaniline) 4,6-dimethylpyrimidine and trichloroacetyl chloride undergo condensation reaction to form the target product. The product has a good bactericidal effect on the fungus Aspergillus.

5-Trichloromethyl-5-hydroxy-2-isoxazoline is an intermediate for pesticides and pharmaceuticals. In the presence of a base, trichloroacetyl chloride and vinyl ether are added, and then cyclic condensation occurs with hydroxylamine to obtain the product. At 10~20 ℃, 18.2 g of trichloroacetyl chloride was added to 7.2 g of vinyl ether and 7.9 g of pyridine, stirred at room temperature for 4 h, and then 6.95 g of hydroxylamine hydrochloride and 10 mL of water were added to obtain a mass fraction of 92%. product.

Trichloroacetyl chloride was added dropwise to the melted mixture of 2,6-dichloro-4-nitroaniline and trichloroacetic acid, and then reacted at 130 °C for 4 h to obtain the product with a yield of 81%. The dosage of pesticide is 2 kg/km 2 , the weed control rate is 95%.


  1. Trichloroacetyl chloride – WikiPedia
  2. Sun Yong. Synthesis and application of trichloroacetyl chloride [J]. China Chlor-Alkali, 2008(11):30-32.

Trichloroacetyl chloride Supplier and Manufacturer

As a trichloroacetyl chloride supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best trichloroacetyl chloride raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for trichloroacetyl chloride and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

Quality Control of Trichloroacetyl chloride

Hot Sale Products

Comments from Customers

Chancelle Makongo
Chancelle MakongoReland
Read More
Its been an absolute pleasure working with this supplier they offered me kindness, support, kept in contact with right up util receive the product the quality is excellent and shipping was fast. overall | am happy and will be returning back for more.
Lio Lechat
Lio LechatSwitzerland
Read More
I can only advise to do business with because the service is excellent!
Thomas Rsel
Thomas RselAustralia
Read More
Great company! thanks from Australia for good product quality, correct product, good customer service using chat.. delivery speed was ok, via FedEx. the Alibaba App finally makes it safer, so good companies like Shandong Zhi Shang can do business with us, I don't have to worry now with Alipay. Everything is safe for me now, I can't go wrong. frst time payments can just use card, the seller never knows your details, only Alibaba does the payment, so the risk is gone, delivery on time is guaranteed, and because the seller can't see your card details, scammers can't use this system, only good companies that do the right thing can make money here. it really is a much better system now.
Daniel Simonson
Daniel SimonsonUnited States
Read More
Great service - the order arrived sealed in a metal can, perfect for shipping. The can was dented but intact.Shipping from China is rough!
rintero ariura
rintero ariuraJapan
Read More
The product was good and the person who dealt with it was kind!
Rene van Buuren
Rene van BuurenJnited Kingdom
Read More
Mary once again exceeded expectations with her friendly, helpful, professional service. I feel very confdent in this company and its products and will definitely be placing further orders in the future.
Barbara Mohar
Barbara MoharSlovenia
Read More
I general, was very satisfied with the supplier. Basic analyzes (m.p.. FTIR) of the product in our facility confirmed its high quality. Further analyzes are planned, but due to the COVID-19 pandemic, most laboratories in Slovenia are closed.
Sergio Masala
Sergio MasalaSpain
Read More
At this moment I did two mini batches of soap with a very good result. But Ihave to improve my procedure in this techinc. Thank you.
Bassam Zaidan
Bassam ZaidanSaudi Arabia
Read More
The product has a very good quality and it was what we were looking for. shipping was on-time even due COVID-19. the supplier was very responsive and with us all the way.

Get Trichloroacetyl chloride Quotation

Scroll to Top