Trans-1,2-Dichloroethylene CAS 156-60-5

Trans-1,2-dichloroethylene has low toxicity and active chemical properties. It is mainly used in the industry as an extractant for heat-sensitive substances or a solvent for some polymer materials and as a raw material for organic synthesis. Its application examples are as follows:

• Preparation of low greenhouse effect environmental protection cleaning agent
  This environmentally friendly cleaning agent uses trans-1,2-dichloroethylene as the main component, which is the ultimate substitute for ozone-destroying substances. It is also a solvent-based azeotropic precision electronic cleaning agent with low greenhouse effect and compliance with the occupational disease prevention and control law. It belongs to the key technology products of clean production. This alternative application plan of environmental protection cleaning agent will try to realize at the current technical stage, on the premise of fully meeting the environmental protection policy of my country as a developing country and the more stringent regulations of developed countries, such as the REACH standard of the European Union and the ACGIH health requirements of the United States , Japan’s air pollution regulations, etc., to meet the requirements of green suppliers.

  The beneficial effect of this patent application compared with the previous technology is to solve the flash point problem of using pure trans-1,2-dichloroethylene, which can be directly applied to existing cleaning equipment; Occupational disease prevention and control problems; solve the replacement of cleaning agents with high greenhouse effect GWP; can replace high-cost cleaning agents to achieve the purpose of reducing costs.

• Preparation of pine caterpillar sex pheromone
  Using 2-hexyn-1-alcohol as the starting material, the transfer of the triple bond position occurs under the action of lithium and propylenediamine to obtain 5-hexyn-1-alcohol; The reaction of dihydropyran yields THP-protected 1-THP-5-hexyn-1-ol on the hydroxyl group, which is coupled with trans-1,2-dichloroethylene under the co-catalysis of metal palladium and cuprous iodide The reaction generates conjugated enynes (7E)-1-THP-8-chloro-5-yne-7-ene-1-octanol;

  (7E)-1-THP-8-Chloro-5-yne-7-ene-1-octanol is further coupled with bromobutane Grignard reagent under the catalysis of metal iron to obtain (7E)-1 -THP-5-alkyne-7-ene-1-dodecanol, which under the catalytic reduction of metal zinc gives (5Z, 7E)-1-THP-dodecadienol; (5Z, 7E)-1 -THP-dodecadienol removes the THP protecting group under the condition of camphorsulfonic acid to obtain the final target product (5Z, 7E)-dodecadienol; the synthetic raw material of the present invention is easy to get, the cost Inexpensive; mild reaction conditions, simple operation, high yield and good stereoselectivity.