Tetraacetylethylenediamine CAS 10543-57-4

British License GB1335204 divulges that the first step is to synthesize oxalylethylenediamine (DAED) with ethylenediamine and acetic acid, and after that accomplish the second step of acetylation with acetic anhydride. European license EP8369 discloses that continual procedure is embraced, and ethylenediamine and acetic anhydride are directly manufactured on a distillation column, yet it needs to make use of expensive acetic anhydride as a basic material for acetylation, as well as the price is incredibly high. British licenses GB20-96133A and also GB2106903A disclose making use of double-column reactors. The very first column finishes the response of acetic acid as well as ethylenediamine, the 2nd column executes acetylation of acetic anhydride, as well as the byproducts are gone back to the first column for reuse instead of acetic acid.

In the two-step synthesis response, in order to boost the reaction performance, a dehydrating agent is usually included in create an azeotrope with water. Catalysts such as phosphoric acid, sulfuric acid, boric acid, zinc acetate, and so on are added in the 2nd step reaction. However, the added drying out agent typically produces side responses with acetic acid and acetic anhydride. At the same time, given that the reaction speed of acetic anhydride as well as diacetylethylenediamine is slow, it is needed to raise the response temperature level to accelerate the reaction rate. Consequently, the basic reaction temperature is above 135 ° C to acquire a greater yield. Nevertheless, the boost of response temperature level will certainly boost the side reactions, and the shade of the acquired product will be strengthened, which will influence the appearance high quality of TAED items.

CN1255376C reveals a kind of prep work approach of tetraacetylethylenediamine, manufactures diacetylethylenediamine by ethylenediamine and also acetic acid, then manufactures tetraacetylethylenediamine by diacetylethylenediamine and acetic anhydride, is characterized because in synthesis reaction Include azeotropic solvent with acetic acid; include triethanolamine tungstosilicate, tetra-tert-butylammonium chloride, activated clay as well as p-toluenesulfonic acid as a catalyst in the synthesis reaction; ethylenediamine The molar ratio of reaction with acetic acid is 1:2.3 ~ 3.0, and the reaction temperature level is 90 ~ 120 ° C; the molar ratio of diacetylethylenediamine as well as acetic anhydride is 1:4 ~ 9, as well as the synthesis response temperature is 110 ~ 132 ° C.

The tetraacetylethylenediamine prepared by the development has a white look and a purity of greater than 99%, and the adoption of the creation has exceptional advantages.