Sodium Salicylate CAS 54-21-7

Factory Supply Sodium Salicylate CAS 54-21-7 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Sodium Salicylate Supplier & Manufacturer

Basic Info

What is Sodium Salicylate?

Sodium salicylate, HOC6H4COONA, is a shiny white powder with wonderful taste as well as light aromatic smell, and also is soluble in water, glycerin as well as alcohol. Used in medication and also as a preservative.

Sodium salicylate can be prepared by adding equimolar ratio of salicylic acid and sodium bicarbonate in water solution; Evaporate to dry to get white salt. In solution, especially in the presence of sodium bicarbonate, the salt will darken when standing still. This is the preferred salt for salicylate drugs. It is usually taken together with sodium bicarbonate to reduce stomach discomfort, or in the form of enteric-coated tablets. However, it is not recommended to use sodium bicarbonate because it will reduce the plasma level of salicylate and increase the excretion of free salicylate in urine.

Although sodium salicylate is not as effective as aspirin in relieving pain, it has less irritation to the gastrointestinal tract and is very useful for patients with aspirin allergy.

Sodium Salicylate Uses

  1. Cuticle relaxant.
  2. Sodium salicylate is made use of to make aspirin, methyl salicylate and also various other salicylates. Azo color coupling agent.
  3. Organic artificial raw materials, chemicals, reagents for gauging totally free acid in stomach juice. Antipyretic and analgesic medicines and anti-rheumatic drugs.
  4. Sodium salicylate used for microanalysis as well as determination of uranium dioxide as well as organic synthesis, and likewise made use of as antibacterial.
  5. Sodium salicylate is used as an analgesic and antipyretic in medicine. Salt salicylate can additionally be used as a non-steroidal anti-inflammatory medicine (NSAID) to cause apoptosis and necrosis of cancer cells. For those that are sensitive to it, it is also a prospective alternative to aspirin. It can also be used as a phosphor to discover vacuum cleaner ultraviolet radiation as well as electrons.

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Sodium Salicylate and Aspirin

Sodium Salicylate is a metabolite of acetylsalicylic acid (sc-217570), which can inhibit NF κ B and minimize oxidative stress and anxiety. In rat research studies, this reagent can prevent the neurotoxicity caused by glutamate. Along with pain killers (sc-202471), sodium salicylate is an anti-inflammatory substance that can bind and also hinder IKK β 。 Salt salicylate has actually been revealed to minimize ATP binding artificial insemination as well as in vivo. Salt Salicylate is an inhibitor of c-Jun and Cox-2 and an activator of p38.

Sodium salicylate is “other” non-prescription salicylate. Its qualities are similar to those of aspirin, with one significant exception: salt salicylate is not acetylated. For that reason, it does not have a two-compartment half-life like pain killers. That is to claim, although the “very first” half-life of aspirin is acetylsalicylic acid, about 15 mins, adhered to by the energetic metabolite salicylate, with a half-life of 3 to 5 hours, the half-life of sodium salicylate is 3 to 5 hours, however it can be included 19 hours. The 2nd significant difference between aspirin and salt salicylate is that acetylation of pain killers does not obstruct cyclooxygenase reversibly. Consequently, pain killers can properly inhibit platelet aggregation as well as prolong platelet life.

Compared with pain killers, sodium salicylate is considered to be less effective in easing pain. However, some patients who are allergic to pain killers may endure sodium salicylate.


  1. Sodium salicylate – WikiPedia
  2. Schwenger, Paul; Edward Y. Skolnik; Jan Vilcek (1996-04-05). “Inhibition of Tumor Necrosis Factor-induced p42/p44 Mitogen-Activated Protein Kinase Activation by Sodium Salicylate”The Journal of Biological Chemistry

Sodium Salicylate Supplier and Manufacturer

As a sodium salicylate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best sodium salicylate raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for sodium salicylate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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