Sodium Cocoyl Isethionate CAS 61789-32-0 SCI

Factory Supply Sodium Cocoyl Isethionate CAS 61789-32-0 SCI with Best Price

  • Appearance: White powder or noodle/granule 
  • Assay: 98. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Sodium Cocoyl Isethionate Supplement

Basic Info of Sodium Cocoyl Isethionate

What is Sodium Cocoyl Isethionate?

Sodium cocooyl hydroxyethyl sulfonate (SCI) is an important surfactant component in mild synthetic detergent (synthetic detergent) cleaning soap. 

Sodium Cocoyl Isethionate for Hair

In hair care products, sodium cocooyl hydroxyethyl sulfonate helps to increase the viscosity of the formula and make it have a thick creamy consistency. It can decompose the oil stain on the surface and dissolve the oil stain and dirt on the surface, so it is easier to remove the dirt and dirt during washing.

Sodium Cocoyl Isethionate for Skin

Sodium cocooyl hydroxyethyl sulfonate, derived from coconut, is a mild soap free detergent known for reducing the damage to the skin barrier; Suitable for sensitive skin.

sodium cocoyl isethionate

Reference

Sodium cocoyl isethionate – ChemicalBook

The Manager has Something to Say

william

This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

Contact Us
  • Email: sales002@sdzschem.com
  • Phone: +86 176 5311 3209
  • WhatsApp: +86 176 5311 3209
  • Weixin: Zhishang17653113209
  • Skype: +86 176 5311 3209
Facebook
Twitter
LinkedIn
Pinterest
Email
WhatsApp
If you want to buy sodium cocoyl isethionate, pls contact us to get a free quote.

Why is sodium cocooyl hydroxyethyl sulfonate (SCI) mild to the skin barrier- In vitro study based on the relative size of SCI micelles and skin pores

In vitro and in vivo studies show that SCI is mild and less harmful to skin barrier than surfactants such as soap and sodium dodecyl sulfate (SDS). We recently showed that SDS forms small micelles in the aqueous solution contacting the skin relative to the water pores in the stratum corneum (SC). Therefore, SDS micelles contribute to SDS skin penetration and cause skin barrier disturbance. 

In this paper, we tried to explain the documented skin mildness of SCI by examining the size of SCI micelles relative to water pores in SC. To this end, we measured mannitol skin permeability and average skin resistivity in vitro when the skin was exposed to aqueous SCI contact solution in the context of the hindered transport aqueous porous pathway model of SC. These in vitro studies show that, SCI micelles with a radius of 33.5 + / – 1 angstrom (determined using dynamic light scattering measurements) have significant steric hindrance and cannot penetrate into SC 5 angstrom through water holes with an average radius of 29 + / – 1 angstrom. 

We believe that the failure of SCI micelles to promote SCI skin penetration and associated skin barrier disturbance is the reason for the observed mild nature of SCI skin. Through use (14) In vitro quantitative skin radioactivity determination of C radiolabeled SCI and porcine full-thickness skin (p-fts), we also finally proved that the skin penetration of SCI was independent of dose. This important finding provided additional evidence that SCI micelles could not penetrate into SC through the small water holes existing in SC, so they could not cause skin barrier disturbance.

Preparation of Sodium Cocooyl Hydroxyethyl Sulfonate (SCI)

Add 498.6g of choline chloride to the beaker, then add 1000g of pentafluoroethanesulfonic acid dropwise to the beaker, keep stirring during the dropping, and stir at room temperature until it is completely dissolved to obtain the proportion of choline chloride-pentafluoroethanesulfonic acid. Fluoroethanesulfonic acid eutectic solvent. Add 950.0 g of coconut oil to the reactor, 500.0 g of sodium hydroxyethyl, and 1425.0 g of choline chloride-pentafluoroethane sulfonic acid eutectic solvent, turn on the stirring, and after nitrogen replacement for three times, keep nitrogen blowing , Raise the temperature to 140℃, and react with timing for 110min; after the reaction is finished, it is cooled to room temperature, 3990.0g of absolute ethanol is added to the reactor twice to wash and extract the products and raw materials, and the raw materials are extracted by positive pressure filtration. The latter anhydrous ethanol was separated, and the final product yield was 88.5%.

Quality Control of Sodium Cocoyl Isethionate

Comments from Customers

Chancelle Makongo
Chancelle MakongoReland
Read More
Its been an absolute pleasure working with this supplier they offered me kindness, support, kept in contact with right up util receive the product the quality is excellent and shipping was fast. overall | am happy and will be returning back for more.
Lio Lechat
Lio LechatSwitzerland
Read More
I can only advise to do business with because the service is excellent!
Thomas Rsel
Thomas RselAustralia
Read More
Great company! thanks from Australia for good product quality, correct product, good customer service using chat.. delivery speed was ok, via FedEx. the Alibaba App finally makes it safer, so good companies like Shandong Zhi Shang can do business with us, I don't have to worry now with Alipay. Everything is safe for me now, I can't go wrong. frst time payments can just use card, the seller never knows your details, only Alibaba does the payment, so the risk is gone, delivery on time is guaranteed, and because the seller can't see your card details, scammers can't use this system, only good companies that do the right thing can make money here. it really is a much better system now.
Daniel Simonson
Daniel SimonsonUnited States
Read More
Great service - the order arrived sealed in a metal can, perfect for shipping. The can was dented but intact.Shipping from China is rough!
rintero ariura
rintero ariuraJapan
Read More
The product was good and the person who dealt with it was kind!
Rene van Buuren
Rene van BuurenJnited Kingdom
Read More
Mary once again exceeded expectations with her friendly, helpful, professional service. I feel very confdent in this company and its products and will definitely be placing further orders in the future.
Barbara Mohar
Barbara MoharSlovenia
Read More
I general, was very satisfied with the supplier. Basic analyzes (m.p.. FTIR) of the product in our facility confirmed its high quality. Further analyzes are planned, but due to the COVID-19 pandemic, most laboratories in Slovenia are closed.
Sergio Masala
Sergio MasalaSpain
Read More
At this moment I did two mini batches of soap with a very good result. But Ihave to improve my procedure in this techinc. Thank you.
Bassam Zaidan
Bassam ZaidanSaudi Arabia
Read More
The product has a very good quality and it was what we were looking for. shipping was on-time even due COVID-19. the supplier was very responsive and with us all the way.
Previous
Next

Hot Sale Products

Get Sodium Cocoyl Isethionate Quotation

Scroll to Top

LEAVE YOUR MESSAGE

Send your inquiry to us. Please feel free to contact us if you have any questions.