Sodium Chloride CAS 7647-14-5

Sodium chloride is an important regulator of electrolyte balance in body fluids. The average amount of sodium in a normal human body is 150g, of which 44% exists in the extracellular fluid in the form of sodium chloride, and about 9% exists in the cells. A constant osmotic pressure in the body is necessary to maintain life, and sodium ions account for 90% of the cation content in extracellular fluid. Therefore, sodium is an important component to maintain the osmotic pressure and capacity of extracellular fluid. The concentration of sodium chloride in the blood is often maintained at a level of 0.6%. This concentration of sodium is a necessary condition for maintaining cell excitability and neuromuscular irritability. If a large amount of sodium is lost in the body, it can cause hyponatremia syndrome.

Sodium chloride injection can replenish blood volume and sodium ions, and can be used clinically for various salt-deficiency dehydration diseases (such as severe vomiting and diarrhea caused by extensive burns, profuse sweating and bleeding, etc.). When there is massive bleeding and blood transfusion cannot be performed, its injection can be infused to maintain blood volume.

1. The effect of sodium chloride on the interaction between myofibrillar protein and flavor substances. Seventeen typical alcohols, aldehydes, ketones and esters were selected to study the adsorption relationship between myofibrillar protein and the above substances and the effect on the protein structure at the concentration of 0.0-1.0mol/L sodium chloride. The results showed that the surface hydrophobicity of myofibrillar protein increased significantly when the concentration of sodium chloride was 0.0~0.4mol/L, and decreased significantly when the concentration of sodium chloride was 0.4~1.0mol/L; when the concentration of sodium chloride was 0.0~0.4mol/L α-helices and β-sheets were transformed into β-turns, and there was no significant change thereafter; myofibrillar protein had weak adsorption to alcohols, and the adsorption of alcohols, ketones and aldehydes decreased as the concentration of sodium chloride increased; The adsorption of esters tends to decrease when the concentration of sodium chloride is 0.0~0.4mol/L, and tends to increase when the concentration of sodium chloride is 0.4~1.0mol/L. The decline of protein adsorption to aldehydes and ketones may be due to the shielding of the Schiff base binding site due to changes in the secondary structure in the early stage, and may be due to the decrease in hydrophobic force in the later stage; the trend of adsorption to esters is opposite to that of hydrophobicity, which is Because the electrostatic interaction is the main binding force.
2. The role of NaCl in the formation of spherical nanocerium oxide. Using hydrated cerium carbonate as raw material, using sodium chloride as grinding aid and polymerization inhibitor, spherical nano-cerium oxide was prepared by mechanical activation method, and the mass ratio of hydrated cerium carbonate to sodium chloride, ball milling time, and calcination were studied by XRD method. The effect of temperature on the grain size of CeO2 powder, and observe the morphology of the final product particles with TEM. The results show that: in the ball milling process of cerium carbonate and its subsequent calcination process, the existence of sodium chloride has played a very good role in grinding aid and polymerization inhibition, and the obtained CeO2 is a spherical particle with good dispersion and a grain size of about 30-50nm.
3. Many substances can be prepared from sodium chloride. Sodium chloride is an important chemical raw material for the preparation of chlorine gas, sodium metal, caustic soda, soda ash, etc., and is widely used in dyes, ceramics, metallurgy, leather, soap, freezing, etc. In analytical chemistry, sodium chloride is a reagent for determining fluorine and silicate, and a standard reagent for calibrating silver nitrate. Sodium chloride is the main salt to maintain the balance of osmotic pressure in the body. A large amount of salt is supplied for consumption and preserved food. When sodium chloride is deficient in the human body, severe dehydration will result.