
Sodium Butyrate CAS 156-54-7



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- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Sodium Butyrate Supplier & Manufacturer
Sodium Butyrate: The Complete Guide
- Item 1: Basic Info of Sodium Butyrate
- Item 2: What is Sodium Butyrate?
- Item 3: Sodium Butyrate Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of sodium butyrate in pig production
- Item 6: Preventative measures when including sodium butyrate to feed
- Item 7: Quality Control of Sodium Butyrate
- Item 8: Hot Sale Products
- Item 9: Get Sodium Butyrate Quotation
Sodium Butyrate for Sale
Basic Info of Sodium Butyrate
Chemical Name: | Sodium Butyrate |
Other Name: | ButanoicacidsodiuMsalt; Sodium butyrate supplement; Natriumbutyrat |
CAS: | 156-54-7 |
EINECS: | 205-857-6 |
Type: | Food additives; Feed additives; Organic raw materials; Inorganic salts; Veterinary raw materials; Pharmaceuticals, dyes and pesticide intermediates |
Molecular Formula: | C4H7NaO2 |
Molecular Weight: | 110.09 |
Melting point | 250-253 °C (lit.) |
density | 1.324 g/cm3 (30℃) |
storage temp. | Store below +30°C. |
solubility | Methanol (Slightly), Water (Slightly) |
form | Amorphous Powder |
color | White |
Water Solubility | soluble |
Sensitive | Hygroscopic |
Stability: | Stable. Incompatible with strong acids. |
Brand Name: | Zhishang Chemical |
Provide: | Sodium Butyrate MSDS; Sodium Butyrate COA |
What is Sodium Butyrate?
Salt butyrate is a substance with the molecular formula Na (C3H7COO). It is a sodium salt of butyric acid. It has many results on cultured animal cells, including inhibiting spreading, inducing distinction as well as generating or preventing gene expression. As a result, it can be made use of busy to generate any one of these results. Especially, butyrate treatment of cells will lead to excessive acetylation of histones, and also butyrate itself will hinder the activity of class I histone deacetylase (HDAC), particularly HDAC1, HDAC2, HDAC3 and also butyrate can be utilized to establish histone deacetylene in chromatin structure and also feature. It is approximated that inhibition of HDAC task influences only 2% of mammalian genetics expression.
Busy, salt butyrate is typically a white water-soluble crystalline strong. This chemical is well-known for its extremely solid and also undesirable scent. When making use of salt butyrate, gloves, safety glasses as well as respirator are advised for safety and security factors.
The substance exists in human diet, specifically in large quantities from dietary fiber in the intestinal tract, and also exists in Parma cheese and also butter. However, the most common resource of sodium butyrate in the intestine is edible beans.
Sodium Butyrate Uses
- Salt butyrate is a substance with the molecular formula Na (C3H7COO). It is a sodium salt of butyric acid. It has numerous impacts on cultured mammalian cells, consisting of preventing spreading, causing distinction and also generating or inhibiting genetics expression.
- Sodium butyrate is an inhibitor of histone deacetylase task (HDAC), which can enhance physiological conditions such as Duchenne muscle dystrophy. In addition, when used with various other cytotoxic agents, it might be an antineoplastic representative since they have actually been verified to be able to deal with cancer.
- Sodium butyrate is one of the feed additives allowed to be used in China and was listed in the List of Feed Additives by the Ministry of Agriculture in 2006. The application mode in animal production is mainly to add sodium butyrate products in animal feed, which plays the role of intestinal mucosa nutrient, electrolyte balance regulator, gastrointestinal microecology regulator, compound acidifier, fragrance agent, food attractant, etc.
- Sodium butyrate has been utilized for:
- As an element of homogenate as well as immunoprecipitation barrier, it is utilized to prevent HDAC in fly embryos and also insect s2 cells.
- As a histone deacetylase prevention in breast cancer cell line MDA-MB-231, it was examined by cell feasibility assay and also virus duplication assay.
- To boost the production of recombinant cells plasminogen activator (t-PA) in Chinese hamster ovary (CHO) cells in a bioreactor.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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Application of sodium butyrate in pig production
Due to the incomplete growth of numerous body organs, pigs will have looseness of the bowels after weaning, leading to growth retardation or death. A multitude of researches have actually revealed that adding salt butyrate to the feed can improve the immunity of hogs as well as boost development performance to varying degrees. Piva et al.
(2002) found that including 0.8 kg of sodium butyrate per ton of acidifier-containing diet regimens and also feeding weaned pigs for 2 weeks could boost the everyday weight gain by 20% and also raise the day-to-day feed intake by 16%. Luo Haixiang (2006) revealed that feeding weaned piglets with sodium butyrate can increase the proportion of villus elevation to crypt deepness, consequently boosting the digestion and absorption feature of pigs and also decreasing the incidence of diarrhea in pigs (P< 0.05)., while raising the daily growth price of pigs.
(2011) discovered that adding different solutions of butyric acid to the diet of weaned pigs on the 28th diet plan can substantially decrease the looseness of the bowels rate of piglets, improve the feed-to-meat ratio, and enhance manufacturing efficiency. Li Dandan et al.
(2012) located that sodium butyrate can advertise the growth of the body immune system of discouraged hogs, enhance the material of immune hemoglobin as well as enhance, as well as successfully stimulate the body to secrete IgA+ cells, thus enhancing the immune function of discouraged piglets and also improving pigs. survival price.
Sodium butyrate has a special smell. It is precisely as a result of this unique physical building that when sodium butyrate is contributed to the feed, the pig will certainly increase the feed intake as a result of the inductive effect of the feed on the pig. At the same time, salt butyrate can also boost pig immune feature, therefore enhancing production performance. Flavor Minghong et al. (2010) discovered that including 0.1% sodium butyrate to the diet of 40kg healthy and balanced Du × Da × Long ternary crossbreed pigs boosted the day-to-day weight gain by 1.26% throughout the whole test period, and the skin color as well as hair condition were substantially far better than those of the control. (P< 0.05).
Tang Minghong et al. (2010) likewise located that sodium butyrate can boost the carcass quality of growing-finishing pigs, considerably enhance the length of duodenal villi and intestinal tract glands; significantly raise the concentration of blood sugar and total protein in lotion, as well as reduce the focus of product in product. The content of urea nitrogen; substantially increased the degrees of IgM, IgG and also IgA in serum (P< 0.05).
Sodium butyrate can advertise the spreading of intestinal mucosal immune cells and also boost the immunity of sows; sodium butyrate has an excellent feeding effect, which can boost the feed consumption of plants. At the same time, sodium butyrate is a quick power for digestive epithelial cells. source, and advertise the absorption of short-chain fatty acids, therefore increasing the milk fat price as well as milk production in milk; additionally, salt butyrate can get to hogs with milk, promote the advancement and also maturity of the gastrointestinal tract of piglets, maintain the wellness of the intestinal tract, and decrease yellow and white looseness of the bowels in pigs and the occurrence of diarrhea signs. Liu Zhijie et al.
(2001) discovered that butyrate can promote hemoglobin synthesis by causing globin genetics expression, specifically to promote the increase of fetal hemoglobin synthesis, improve the oxygen-carrying capacity of the umbilical cord, as well as make sure that the newborn piglets are properly nourished and strenuous. Mao Shiming (2010) located that adding 400 as well as 600 g/t of covered salt butyrate to the diet plan of plants in the late gestation enhanced the high quality of the hogs’ litters by 1.44% and 1.90%, and also the top quality of the babies by 2% and 2.6%, specifically. After 28 days of lactation, the weaned individual top quality as well as ordinary day-to-day weight gain of pigs were boosted by 4.71%, 6.99% and 5.41%, 8.63%, specifically.
Preventative measures when including sodium butyrate to feed
- Dosage
It is needed to take notice of the web content of salt butyrate included in the feed. The content of salt butyrate needed by various animals, ages, physiological conditions and reproducing atmospheres will certainly be various. Generally speaking, it is more appropriate to add 500 ~ 4000 mg/kg to pig feed, and the specific amount needs to be identified by a great deal of experiments. - Use resources
Although sodium butyrate itself is non-toxic, it is harsh, as well as a little recklessness can trigger burns and endanger human wellness. Consequently, when configuring feed, you should pay attention to your own security. At the same time, when storing sodium butyrate, it should be kept in a completely dry as well as awesome location. - Quality of raw materials
Salt butyrate has great fluidity, is very easy to combine with various other feeds, as well as does not alter the pH of the feed. Nevertheless, it should be noted that the oral mucosa of pets is soft and has solid sensitivity. If low-quality and also rough chemical grade sodium butyrate is made use of as a food attractant, it will create burns to animal mucosa, leading to lowered feed consumption and even refusal to feed. Therefore, the quality of sodium butyrate resources need to be purely regulated when creating diet plans.
Reference
- Sodium butyrate – WikiPedia
- Talking about the application of sodium butyrate in pig production
Sodium Butyrate Supplier and Manufacturer
As a sodium butyrate supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best sodium butyrate raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have demand for sodium butyrate and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.
Pre-Sales Service
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*Any inquiries will be replied within 24 hours.
*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
After-Sales Service
*The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
*Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Is there a discount?
Different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
1. ≤50kg, Express delivery recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
Quality Control of Sodium Butyrate

