Sericin A Sericin Powder CAS 60650-88-6


Sericin A Sericin Powder CAS 60650-88-6


Basic Info

CAS No.:




Place of Origin:

Shandong, China


White to light yellow powder

Brand Name:

Zhishang Chemical

Product name:

Sericin powder


Comestic Grade


Cool Dry Place


White to light yellow powder

Shelf life:

2 Years


Other Names:

Sericin A






Cosmetic Raw Materials, Detergent Raw Materials

Model Number:







25 Kg


1KG/Foil Bag 25kg/Drum

Test Method:



Product NameSericin
Stockin stock


Sericin is a natural macromolecular protein wrapped on the surface of silk fibroin. It is mainly secreted by the silk glands of silkworms and is one of the main proteins that make up silkworm cocoons.
Sericin is widely used for its good water solubility, promoting cell adhesion and proliferation activity, lower immunogenicity, and unique in situ fluorescence, antioxidant activity and tyrosinase inhibitory properties. Fabric finishing coatings, cosmetic additives, as well as food, medicine, and functional biological materials.

Chemical Properties:

  1. Sericin has amphoteric properties and isoelectric point. Sericin contains free shuttle groups and amino groups, which can interact to form bipolar ions and has amphoteric properties. In a solution with a lower pH value, sericin exists in the form of positive ions in a solution with a larger value, and sericin exists in the form of negative ions. The isoelectric point of sericin is 3.8-4.5.
  2. The colloidal properties of sericin.Sericin is a polymer compound with a large molecular weight and a particle diameter of 1-100nm. Since the particle size is within the range of colloidal particles, it shows the unique dialysis, aggregation, and coagulation characteristics of the sol. Gelation and peptization properties.
  3. Sericin denatured sericin molecules often change when they are affected by some external physical or chemical factors, but these changes do not involve changes in the primary structure, and the covalent bond of the skin chain is not broken, just There has been a change in molecular conformation, which causes a change in properties. Its main manifestations are changes in physical properties, chemical properties, and loss of biological activity. The most prominent manifestation is decreased solubility, which will greatly reduce its use value. The main factors that cause the denaturation of sericin are temperature, pH and organic solvents.
  4. Sericin swelling and dissolving Sericin is a macromolecule. When it comes into contact with a proper liquid, it will automatically absorb the liquid and swell and become soft. After infinite swelling, it can dissolve in the liquid. Under normal circumstances, silk fibroin can only swell and not dissolve in water, but sericin can dissolve in hot water. This is the most important property of sericin, and it is also the basis for people to use water to make silk, scouring and degumming.


  • Application in the field of cosmetics Generally speaking, the stratum corneum of normal skin should retain 10%-20% of water in order to make the skin elastic, full and shiny without cracking. The reason why the stratum corneum retains a certain amount of water is because, on the one hand, the sebum film has the ability to prevent water from evaporating, and on the other hand, the stratum corneum contains natural moisturizing factors (NMF) with moisture absorption and moisturizing functions; sericin is rich Containing polar amino acids, it contains polar groups such as -OH, -COOH, -NH2, and has similar ingredients and functions to moisturizing factors. Japan has cosmetics containing sericin, such as moisturizers, facial cleansers, and facial cleansers. Wait. Studies have shown that skin darkening is due to the oxidative effect of tyrosinase in melanocytes. Yamada Hideyuki’s research has found that sericin can inhibit the activity of this enzyme, and it still retains this ability after boiling. In sericin, tyrosine (Tyr), tryptophan (Trp) and phenylalanine (Phe) can absorb ultraviolet rays, so that the skin will not be tanned and sunburned.
  • Applications in the edible field More than 90% of the amino acids contained in sericin can be absorbed by the human body, and more than 17% of the amino acids contained in the amino acids necessary for the human body. Among them, serine, glycine, and aspartic acid have special pharmacological effects: serine can effectively inhibit the increase of cholesterol in the blood, and can prevent and treat high blood pressure; inhibit tuberculosis, can be used to treat lung diseases. Glycine can lower cholesterol at the same time, and has the effect of lowering blood sugar, preventing and treating thrombosis, blood coagulation, and curing diabetes. Aspartic acid can lower blood ammonia, protect myocardium, treat angina pectoris, and also protect the liver. Serine and glycine are the nutritional factors of glial cells. Sericin (serine and glycine accounted for about half) can improve memory and prevent dementia. Sericin as an antioxidant can be used in the food industry. Sericin can effectively inhibit fat peroxidation (food oxidation is mainly fat oxidation), and inhibit polyphenol oxidase, thereby inhibiting food browning. The study also found that] Sericin can promote the absorption of zinc, iron, calcium and other elements in mice. Sericin with a larger molecular weight cannot be absorbed by the gastrointestinal tract and is excreted in the feces, which has the function of preventing constipation.
  • The field of fiber modification The silk sericin is fixed on the surface of the fiber fabric through a cross-linking agent, so that the fiber has the original performance and the functional characteristics of sericin, which improves the wearability and value of the fabric. Polyester has high strength and good resilience, but it has poor moisture absorption and air permeability and poor wearing comfort, so it cannot be used as a good fabric for wearing. Surface modification of polyester with sericin can improve the comfort of polyester.
  • Biological materials Many studies have shown that sericin has the ability to be used as a medical dressing. The water-absorbing properties of sericin help the skin surface maintain a relatively moist environment and can absorb the exuded fluid from the wound. Two-dimensional membranes, three-dimensional hydrogels and porous scaffolds prepared with sericin have been reported. In mouse experiments, not only as a dressing, but also as a sericin essence also showed very good wound healing properties, and did not cause allergic reactions. Compared with the control group, the wound treated with sericin showed less inflammation. The wounds were treated with collagen and sericin, and the epidermis of the sericin treatment group grew faster.


Storage condition: Cool Dry Place

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.


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