Sericin Protein CAS 60650-88-6

Factory Supply Sericin Protein CAS 60650-88-6 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Sericin Supplier & Manufacturer

Basic Info

What is Sericin?

Sericin is a protein produced by Bombyx mori in the process of silk manufacturing. Silk is the fiber created in the process of cocooning. It is mostly composed of two proteins, fibroin and also sericin. Silk is composed of 70-80% fibroin as well as 20-30% sericin; Silk fibroin is the architectural facility of silk, and also sericin is the adhesive that covers the fiber as well as makes them stick together.

Sericin consists of 18 various amino acids, 32% of which are serine. The second structure is usually arbitrarily curled, however it can additionally be conveniently exchanged β- Fold conformation. Serine hydrogen bond gives it glue like high quality. The gene inscribing sericin has been sequenced. Its C-terminal component has several serine abundant repeats.

Utilizing gamma ray examination, it was determined that sericin fibers are normally made up of 3 layers, every one of which run in different directivity modes. The innermost layer is generally made up of longitudinal fibers, the middle layer is composed of transverse fiber oriented pattern fibers, as well as the outer layer is composed of fiber oriented fibers. The general structure can also transform according to the temperature level, and the reduced the temperature, β- Folded conformation is typically more than random amorphous coils. There are also 3 various sorts of sericin, which form the top layer of fibroin. The water-insoluble sericin A is the outer layer, consisting of regarding 17% nitrogen, serine, threonine and other amino acids, aspartic acid and glycine. Sericin B, which makes up the middle layer, is practically the like sericin A, however likewise contains tryptophan. Sericin C is the innermost layer, which is closest to and adjacent to fibroin. Likewise insoluble in water, sericin C can be separated from fibroin by including warm weak acid. Sericin C likewise contains amino acids existing in B and also added proline.

Sericin Uses

Sericin is utilized in medicine and cosmetics. Sericin is mainly made use of for medical injury suture as a result of its flexibility, tensile strength as well as natural fondness for keratin. It additionally has natural anti infectivity as well as is extensively made use of due to its superb biocompatibility, so it is likewise widely used as a wound coagulant.

When utilized in cosmetics, sericin has actually been located to boost skin elasticity and a range of anti-aging variables, including anti wrinkle buildings. This is achieved by lessening skin water loss. To identify this, the scientists accomplished a number of experimental procedures, including hydroxyproline dimension, insusceptibility measurement, skin moisture loss as well as scanning electron microscopic lense evaluation of skin solidity as well as dryness. The visibility of sericin will enhance the hydroxyproline in the stratum corneum, therefore minimizing the skin insusceptibility, hence increasing the skin dampness. Adding Planck and Carbomer, two other components that can be consisted of in sericin gel, can fix the all-natural moisturizing variable (NMF), while lessening water loss, thus enhancing skin wetness.

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Application of Sericin

Generally speaking, the normal skin stratum corneum should retain 10% to 20% of the water in order to make the skin elastic, plump and shiny without cracking. The reason why a certain amount of water is retained in the stratum corneum is that, on the one hand, the sebum film has the ability to prevent water evaporation, and on the other hand, the stratum corneum contains natural moisturizing factors (NMF) with hygroscopic and moisturizing functions; sericin is rich in moisture. Contains polar amino acids, which contain polar groups such as -OH, -COOH, -NH2, and have similar ingredients and functions as moisturizing factors. Japan already contains sericin cosmetics, such as body lotion, facial cleanser, facial cleanser Wait. Studies have shown that the darkening of the skin is due to the oxidation of tyrosinase in melanocytes. Hideyuki Yamada’s research found that sericin can inhibit the activity of this enzyme, and it still retains this ability after boiling. In sericin, tyrosine (Tyr), tryptophan (Trp) and phenylalanine (Phe) can absorb ultraviolet rays and prevent the skin from tanning and sunburn.


Sericin – WikiPedia

Sericin Supplier and Manufacturer

As a sericin supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best sericin raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for sericin and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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