S-Adenosyl-L-methionine CAS 29908-03-0 SAM-E

Factory Supply S-Adenosyl-L-methionine CAS 29908-03-0 SAM-E with Best Price

  • Appearance: White powder 
  • Assay: 99. 0%min
  • Packaging: 25kg/drum
  • Sample: Available

Basic Info of S-Adenosyl-L-methionine

What is S-Adenosyl-L-methionine?

SAMe (S-adenosyl-L-methionine, SAM-e) is a metabolite of the combination of sulfur-containing amino acid-methionine and human body’s main energy substance adenosine triphosphate (ATP-adenosinetriphosphate). It is a physiologically active substance that exists in the human body. SAMe is neither a herbal medicine nor a hormone. It is a microparticle molecule that participates in more than 200 biochemical reactions in the human body. S-adenosylmethionine has been pointed out to promote dopamine and serotonin neurotransmitter updates and sensory functions in the brain, and may also have a repairing effect on myelin that surrounds nerve cells.

S-adenosylmethionine is very important for the health and development of many tissues and organs in the human body. It involves more than 10 individual biochemical reactions and precision and processes, such as brain function and joint health. With the help of folic acid and vitamin B. S-adenosylmethionine can provide a positive contribution to every function of the body. Normally, the body makes all the S-adenosylmethionine it needs. However, the lack of ammonium methsulfate, vitamin B or folic acid can reduce the synthesis of S-adenosylmethionine, which can reduce S-adenosylmethionine in the tissues of the elderly and patients suffering from joint, depression and different liver diseases. The quantity is extremely low.

S-Adenosyl-L-methionine Benefits

  1. Application of S-Adenosyl-L-methionine in the treatment of liver disease
    The liver is the main site of SAM synthesis and methylation. If the liver is damaged, the SAM synthesis of patients with liver disease will be blocked, and the synthesis of protein and nucleic acid, and the supply of polyamines and cysteine will be restricted. Cysteine is a synthetic precursor of glutathione, an important hepatoprotective agent. Clinical studies have shown that injection and oral administration of S-Adenosyl-L-methionine can effectively increase the content of glutathione in blood and liver tissue, thereby enhancing the detoxification effect of the liver, reducing or even eliminating liver damage. SAM can cause cholestasis and liver damage caused by alcohol, including liver cirrhosis and cirrhosis. Other liver dysfunctions have curative effects, especially for liver cirrhosis, which can significantly reduce the mortality rate.
  2. Application of S-Adenosyl-L-methionine in the treatment of depression
    As early as 1973, studies have shown that SAM has the effect of treating depression. In the 1980s, SAM was used to treat depression in Europe. SAM is the main methyl donor in the brain and is involved in the synthesis of a variety of neurotransmitters. Due to its transmethylation function, it can promote the metabolism of dopamine in the brain and complex amines in the blood. The methylation of phospholipids helps to enhance receptor function, increase receptor density and improve receptor coupling.Clinical studies have proved that daily injection or oral administration of 200~1600mg SAM can effectively relieve depression, and its effect is better than placebo and equivalent to standard tricyclic antidepressants. S-Adenosyl-L-methionine has a special effect on various depressions, especially postpartum depression, and compared with other similar drugs, it has the advantages of quick action, no addiction, few adverse reactions and good tolerance. The symptoms will usually be obvious within a week. It can be used to treat patients with poor tolerance to other antidepressants, elderly patients, and depression patients with severe liver disease.
  3. Application of S-Adenosyl-L-methionine in the treatment of osteoarthritis
    S-Adenosyl-L-methionine has anti-inflammatory, pain relief and tissue repair functions. Studies have shown that SAM has the same efficacy as the current first-choice drugs for the treatment of arthritis, ibuprofen and naproxen, and has the effect of significantly promoting cartilage formation and reducing joint pain, stiffness and swelling, with few side effects and quick results. As early as the 1970s, Europe had already used SAM as a prescription drug for treating arthritis.
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Comments from Customers

Chancelle Makongo
Chancelle MakongoReland
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Its been an absolute pleasure working with this supplier they offered me kindness, support, kept in contact with right up util receive the product the quality is excellent and shipping was fast. overall | am happy and will be returning back for more.
Lio Lechat
Lio LechatSwitzerland
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I can only advise to do business with because the service is excellent!
Thomas Rsel
Thomas RselAustralia
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Great company! thanks from Australia for good product quality, correct product, good customer service using chat.. delivery speed was ok, via FedEx. the Alibaba App finally makes it safer, so good companies like Shandong Zhi Shang can do business with us, I don't have to worry now with Alipay. Everything is safe for me now, I can't go wrong. frst time payments can just use card, the seller never knows your details, only Alibaba does the payment, so the risk is gone, delivery on time is guaranteed, and because the seller can't see your card details, scammers can't use this system, only good companies that do the right thing can make money here. it really is a much better system now.
Daniel Simonson
Daniel SimonsonUnited States
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Great service - the order arrived sealed in a metal can, perfect for shipping. The can was dented but intact.Shipping from China is rough!
rintero ariura
rintero ariuraJapan
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The product was good and the person who dealt with it was kind!
Rene van Buuren
Rene van BuurenJnited Kingdom
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Mary once again exceeded expectations with her friendly, helpful, professional service. I feel very confdent in this company and its products and will definitely be placing further orders in the future.
Barbara Mohar
Barbara MoharSlovenia
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I general, was very satisfied with the supplier. Basic analyzes (m.p.. FTIR) of the product in our facility confirmed its high quality. Further analyzes are planned, but due to the COVID-19 pandemic, most laboratories in Slovenia are closed.
Sergio Masala
Sergio MasalaSpain
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At this moment I did two mini batches of soap with a very good result. But Ihave to improve my procedure in this techinc. Thank you.
Bassam Zaidan
Bassam ZaidanSaudi Arabia
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The product has a very good quality and it was what we were looking for. shipping was on-time even due COVID-19. the supplier was very responsive and with us all the way.
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