Trimetazidine Impurity 3 CAS 2103-57-3

Molecular Formula: C10H12O4

Formula Weight:196.2

Purity: 99%

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Product Name: Trimetazidine Impurity 3
CAS No:2103-57-3

Basic Info

Product Name:Trimetazidine Impurity 3
Other Names:2,3,4-trimethoxy-benzaldehyd
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Appearance:Crystalline Solid
EINECS No.:218-271-0
Storage:Cool Dry Place
Provide:Trimetazidine Impurity 3 MSDS;
Trimetazidine Impurity 3  COA


Product Categories:

Aromatics, Impurities, Intermediates;BUILDING BLOCKS;Benzaldehyde;API intermediates;(intermediate of trimetazidine.);Aldehydes;Aromatic Aldehydes & Derivatives (substituted);C10 to C21;Carbonyl Compounds


Trimetazidine Impurity 3 is a trimethoxy aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an impurity of the anti-angina pectoris drug trimetazidine (T795610). Trimetazidine is a piperazine derivative Chemicalbook. It is a new type of anti-myocardial ischemic drug. It mainly inhibits myocardial fatty acid β oxidation, increases glucose oxidation, and improves glycolysis by inhibiting 3-ketoacyl-CoA thiolase. Coupling with sugar oxidation to optimize energy metabolism of cardiomyocytes

Chemical Properties:

Crystalline Solid

Melting point 38-40 °C(lit.)
Boiling point 168-170 °C12 mm Hg(lit.)
density 1.2166 (rough estimate)
refractive index n20/D 1.5547(lit.)
Fp >230 °F
storage temp. Inert atmosphere,2-8°C
solubility methanol: 0.1 g/mL, clear
form Crystals or Crystalline Powder
color White to light yellow
Sensitive Air Sensitive


  1. Trimetazidine Impurity 3 is an important pharmaceutical intermediate, which can be used in the synthesis of a new type of drug Ca2+ channel blocker. The drug can be selectively used in the arteries of the brain Chemicalbook to reduce the incidence of headaches. There is a certain demand in the European and American markets. It can also be used as trimetazidine impurity C, which can be used in the development of trimetazidine standards.
About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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