SHANDONG ZHISHANG CHEMICAL CO.LTD.

Nitrofurantoin CAS 67-20-9

Molecular Formula: C10H9N3O

Formula Weight: 187.2

Purity: 99%

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Product Name: Nitrofurantoin
CAS No: 67-20-9

Basic Info

Product Name:Nitrofurantoin
Other Names:1-(((5-nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione;
CAS:67-20-9
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type:antibiotic;Heterocycles;
Appearance:Crystalline Solid
EINECS No.:200-646-5
Storage:Cool Dry Place
Purity:98%
Provide:Nitrofurantoin MSDS;
Nitrofurantoin  COA
Synonyms:

1-(5-NITRO-2-FURFURYLIDENEAMINO)HYDANTOIN;1-[(5-nitrofurfurylidene)amino]hydantoin;LABOTEST-BB LT00134625;FURADOXYL;N-(5-NITRO-2-FURFURYLIDENE)-1-AMINOHYDANTOIN;NITROFURANTOIN;NITROFURANTOINE

Product Categories:

Furan&Benzofuran;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Peptide Synthesis/Antibiotics

Description:

Nitrofurantoin, also known as furantoin, furantoin, nitrofurantoin, nitrofurantoin, chemical name 1-[[(5-nitro-2-furanyl)methylene]amino]-24-imidazolidinedioe, is a synthetic Chemicalbook antibacterial It has a broad antibacterial spectrum and has antibacterial effects on most Gram-positive and negative bacteria, such as Staphylococcus aureus, Escherichia coli, Staphylococcus albicans and Streptococcus pyogenes. It is often used clinically for urinary system infections caused by sensitive bacteria, such as Meng pyelonephritis and urinary tract infections. Cystitis and prostatitis, etc.

Chemical Properties:

Crystalline Solid

Melting point 268°C
Boiling point 380.75°C (rough estimate)
density 1.5824 (rough estimate)
refractive index 1.6700 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: soluble50mg/mL
pka7.2(at 25℃)
form crystalline
color yellow
Water Solubility <0.01 g/100 mL at 19 ºC
λmax358nm(MeOH)(lit.)
Sensitive Light Sensitive & Hygroscopic

 

Application:
  1. The oral dose of nitrofurantoin for adults is usually 50-100 mg, four times daily, with meals and at bedtime. Treatment of this medicine is usually continued for 14 days. The daily dose for children is 5-7 mg/kg, given in four divided oral doses. The dosage should be reduced if continued beyond 14 days or if used for prophylaxis. For long-term treatments, an oral dose of 1 mg/kg is recommended4.
  2. The common side effects of nitrofurantoin happen in more than 1 in 100 people. Nitrofurantoin may cause the patients’ urine turn into dark yellow or a brownish color. This symptom is normal and will disappear after stopping taking nitrofurantoin. Mild side effects of nitrofurantoin include feeling sick and vomiting, diarrhea, loss of appetite, headaches, dizziness or feeling sleepy. Serious side effects are rare and happen in less than 1 in 1,000 people. Those symptoms include but not limited to chest pains, difficulty in breathing, coughing, chills, or a high temperature, yellowing of the skin or eyes, tingling sensations, bleeding and bad headache. In emergency cases, it is also possible to have a serious allergic reaction to nitrofurantoin11.
  3. Nitrofurantoin is classified in FDA pregnancy category B. It is not expected to be harmful to an unborn baby during early pregnancy 5, but it is not recommended for the last 2-4 weeks of pregnancy. Nitrofurantoin can pass into breast milk and may harm a nursing baby12. Nitrofurantoin should not be given to a child younger than 1 month old and patients having severe kidney diseases, urination problems or a history of jaundice or liver problems caused by nitrofurantoin13.
About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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