Product Name: N N-Diisopropylethylamine
CAS No: 7087-68-5
|Product Name:||N N-Diisopropylethylamine|
|Place of Origin:||Shandong, China|
|Brand Name:||Zhishang Chemical|
|Type:||APIs and intermediates|
|Appearance:||Clear, colorless to light yellow liquid|
|Storage:||Cool Dry Place|
|Provide:||N N-Diisopropylethylamine MSDS；|
N N-Diisopropylethylamine COA
Organic blocks; Other biochemical reagents; General reagent; Condensation reagent; Fine chemicals; intermediate; Raw materials; Protective amino acids; Condensation agent; Nitrogen compounds; Pharmaceutical intermediates; Amino compounds; Acyclic monoamines, polyamines and their derivatives and salts; Organic raw materials; Esomeprazole sodium; microorganism; Solvent; Organic chemical industry; Analytical purity; Pharmaceutical raw materials; Amine; Industrial raw materials; Biochemical reagents; API and intermediates for synthesizing API; Biochemical industry; Pharmaceutical intermediates; Chemical intermediates; OtherReagents; DetectionofAminesforPrimaryAmines(forDetectionofFreeAmineontheResins); CombinatorialChemistry; SyntheticOrganicChemistry; Chemistry; ACSandReagentGradeSolvenChemicalbookts; AmberGlassBottles; EssentialChemicals; InorganicSalts; ReagentPlus; ReagentPlus; ReagentPlusSolventGradeProducts; ResearchEssentials; SolutionsandReagents; SolventBottles; SolventbyApplication; SolventPackagingOptions; Solvents; construction; Organic synthesis; Organic chemical raw materials; Chemical intermediates – fine chemicals; Organic intermediates; Chemical Reagents; Chemical raw materials; Standard; Intermediate – organic intermediate; Organic reagent; Reagent polypeptide; Fine chemical raw materials; High end synthetic intermediates; APIs and intermediates
- Also known as Hunig’s base and abbreviated as DIPEA or DIEA, N,N-Diisopropylethylamine is a sterically hindered amine and an organic compound. The colourless liquid was named as Hung’s base after Siegfried Hunig, a German chemist. It is noteworthy hat the compound is commercially available.
- In organic chemistry, the compound is used as a base. Since the nitrogen centre is isolated by an ethyl group and the two isopropyl groups, N,N-Diisopropylethylamine can bind to protons. The compound is, therefore, a base similar to 2,2,6,6-tetramethylpiperidine, but a poor nucleophile, a blend of properties that makes it valuable as an organic reagent.
- Traditionally, DIPEA is prepared by the alkylation of diisopropylamine with diethyl sulphate. DIPEA can then be purified through distillation from potassium hydroxide if necessary.
Clear, colorless to light yellow liquid
|Melting point||<-50 °C (lit.)|
|Boiling point||127 °C (lit.)|
|density||0.742 g/mL at 25 °C (lit.)|
|vapor pressure||31 mmHg ( 37.7 °C)|
|refractive index||n20/D 1.457|
|storage temp.||Store below +30°C.|
|Specific Gravity||0.755 (20/4℃)|
|PH||12.3 (H2O, 20℃)(as an emulsion)|
- It is used as a base in organic synthesis. Because the nitrogen atom
- N,N-Diisopropylethylamine is utilized as a base in the palladium(0)catalysed alkoxycarbonylation of both allyl acetates and phosphates . When treated with triphenyphosphine in the presence of DIPEA in ethanol under carbon monoxide pressure, diethyl-2-hexenyl phosphate produces mixtures of cisand trans–ethyl heptenoates in a ratio of 84:16. DIPEA is used as a neutralizer of the produced phosphoric acid. Notably, the alkyl ester cannot be produced without DIPEA.
When combined with boryl triflates, N,N-Diisopropylethylamine is hugely used in the enolate synthesis of ketones for application in directed cross-adol reactions . When reacted with Di-n-butylboryl Trifluoromethanesulfonate and DIPEA in ether, 4-methyl-2-pentanone generates unisolated baron enolate.
The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.
“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.
- Business Type: Manufacturer
- Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
- Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
- Total Employees: 51~100
- Capital (Million US $): 10000000RMB
- Year Established: 2016
- No. of Production Lines : 8
- No. of QC Staff : 5 -10 People
- OEM Services Provided : yes
- Factory Size (Sq.meters) : 3,000-5,000 square meters
- Certificate: ISO9001 , CE , GMP , API , MSDS
- Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.
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Do you accept sample order?
We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Is there a discount?
Different quantity has different discount.
1. ≤50kg, Express delivery recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.