SHANDONG ZHISHANG CHEMICAL CO.LTD.

Itraconazole CAS 84625-61-6

CBNumber: CB4716071

Molecular Formula:C35H38Cl2N8O4

Formula Weight:705.63

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Product Name: Itraconazole              CAS Number: 84625-61-6           Purity: 99%

Basic Info

Product Name:Itraconazole
Other Names:ITRACONAZOLE-D3
CAS:84625-61-6
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type:API
Appearance:White powder
EINECS No.:617-596-9
Storage:Cool Dry Place
Purity:99%
Provide:Itraconazole MSDS;
Itraconazole COA
Synonyms:

ITRACONAZOLE-D3;ITRACONAZOLE;SPORANOX;R51211;ORICONAZOLE;

TRIASPORIN;-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihyd;

3h-1,2,4-triazol-3-one,4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazol.

Product Categories:

API;Metabolite Reference Standard;Active Pharmaceutical Ingredients;Antifungal.

API Reference Standard Free Base API;Related Substance;Antibiotic Explorer.

Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals.

Chemical Properties:

Melting point :166°C
alpha -0.1~+0.1°(D/20℃)(c=10,CH2Cl2)
Boiling point :850.0±75.0 °C(Predicted)
density :1.27 g/cm3
Fp >110°(230°F)
storage temp:2-8°C
solubility chloroform: 50 mg/mL, clear, colorless
pka 3.7(at 25℃)
form White powder
color white
Water Solubility Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck 14,5245
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey VHVPQPYKVGDNFY-UHFFFAOYSA-N
CAS DataBase Reference 84625-61-6(CAS DataBase Reference)

Application:
  1. Itraconazole imidazole antifungal agents for the triazole ring, through inhibiting the activation of cytochrome P-450, including oxidase and peroxidase, disable the 14, α-methyl sterols to be dehydrogenated and be converted to ergosterol, so that the growth and proliferation of fungi are inhibited. They have strong lipophilicity and penetrate through the biofilm to inhibit the binding of the membrane to the fungus. The antibacterial spectrum is similar to ketoconazole.
  2. Itraconazole  is effective in the treatment of superficial fungal diseases such as vaginal and oral candidiasis as well as skin mycosis. Furthermore, it is expected to become the highly-efficient and safe drugs for the treatment of deep fungal infections such as cryptococcal encephalitis (AIDS).
  3. Itraconazole is used for the treatment of vulvovaginal candidiasis, pityriasis and skin fungal disease pityriasis caused by sensitive fungi.
    It can be used for the synthesis of broad-spectrum azole antifungal agents for the treatment of systemic infection caused by deep fungus. It can also be used for the treatment of candidiasis and aspergillosis.
  4. For the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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