1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate CAS 56602-33-6

Molecular Formula: C12H22F6N6OP2

Formula Weight: 442.29

Purity: 99%

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Product Name: 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
CAS No: 56602-33-6

Basic Info

Product Name:1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
Other Names:Phosphorus(1+), (1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-)
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type:Peptide Coupling Reagents;Biochemistry
Appearance:white to off-white powder
EINECS No.:260-279-1
Storage:Cool Dry Place
Provide:1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate MSDS;
1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate COA


Product Categories:

Nitrogen compounds; Peptide bond condensing agent; Coupling reagent; Chemical biology; intermediate; Protective amino acids; Condensation agent; Pharmaceutical raw materials; Polypeptide coupling agent; PharmaceuticalIntermediates; PeptideCouplingReagents; Biochemistry; Condensation&ActiveEsterification; CouplingReactions(PeptideSynthesis); PeptideSynthesis; PhosphoniumCompounds; SyntheticOrganicChemistry; Peptide; peptides; Peptide coupling; Chemical Reagents; Biochemical reagent surfactant; Biochemical reagents – amino acids; Medical raw materials; Chemical Reagents; Biological reagent; Chemical raw materials; MiscellaneousReagents

Chemical Properties:

white to off-white powder

Melting point >130 °C (dec.)(lit.)
Fp 138°C
storage temp. 2-8°C
solubility methanol: 25 mg/mL, clear
form Powder
color White to off-white
Water Solubility Soluble in methanol, acetone and dichloromethane. Insoluble in water.
Decomposition 138 ºC
Sensitive Moisture & Light Sensitive
BRN 4287025


  1. Peptide coupling reagent which suppresses racemization.
  2. 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.
About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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