3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1'-cyclohexan]-4(3H)-one CAS 158299-05-9

CBNumber: CB1474587

Molecular Formula: C16H18BrNO3

Formula Weight: 352.22

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Product Name: 3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1′-cyclohexan]-4(3H)-one               CAS Number: 158299-05-9             Purity: 99%

Basic Info

Product Name:3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1′-cyclohexan]-4(3H)-one
Other Names:3-(2-Bromo-1-oxoprop
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Appearance:White powder
EINECS No.:1806241-263-5
Storage:Inert atmosphere,2-8°C
Provide:3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1′-cyclohexan]-4(3H)-one msds;
3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1′-cyclohexan]-4(3H)-one COA


Product Categories:

Heterocyclic; intermediate; Meropenem intermediate; Pharmaceutical raw materials; Raw materials; Big goods

Chemical Properties:

White powder

  1. It is another semi synthetic carbapenem antibiotic for parenteral administration after imipenem cilastatin was listed in the United States. The synthesis of bacterial cell wall is inhibited by its covalent bond with penicillin binding proteins (PBPs) involved in cell wall synthesis, so as to play an antibacterial role. It is sensitive to Gram-positive bacteria and Gram-negative bacteria, especially Gram-negative bacteria. If the minimum inhibitory concentration (MIC) for about 90% of Enterobacteriaceae is 0.08-0.15mg/l, more than 90% of Pseudomonas aeruginosa strains are highly sensitive to it (MIC < 4mg / lcchemicalbook), and all Haemophilus including ampicillin resistant strains are highly sensitive to it (MIC is 0.06-1mg / L). Neisseria gonorrhoeae was also highly sensitive to meropenem, and its activity was 15 times stronger than imipenem. Staphylococcus epidermidis, saprophytic Staphylococcus and other coagulase negative Staphylococcus are sensitive to meropenem, and most strains of Enterococcus faecalis are highly or moderately sensitive to meropenem. Meropenem with MIC of 0.06-4mg/l can inhibit almost all Bacteroides fragilis. Anaerobic bacteria such as digestive Streptococcus, Propionibacterium and actinomycetes are also sensitive to meropenem.
  2. 3 – (2-bromo-1-oxopropyl) – spiro [2h-1,3-benzoxazine-2,1 ‘- Cyclohexan] – 4 (3H) – one is the synthesis of meropenem series intermediates and mother nuclei
About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get 3-(2-Bromo-1-oxopropyl)-spiro[2H-1 3-benzoxazine-2 1'-cyclohexan]-4(3H)-one Quotation