Polylactic acid CAS 26100-51-6 PLA

Factory Supply Polylactic acid CAS 26100-51-6 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Polylactic acid Supplier & Manufacturer

Basic Info of Polylactic acid

What is Polylactic acid?

Polylactic acid (PLA) is a new type of bio-based and renewable biodegradable material, which is made from starch raw materials proposed by renewable plant resources (such as corn, cassava, etc).

Polylactic acid is an important biomedical polymer material with good biocompatibility and bioabsorbability. It has been widely used in fracture internal fixation, tissue engineering scaffolds, surgical sutures, drug controlled release systems, etc. application. Polylactic acid is usually synthesized by the ring-opening polymerization method of lactide. According to the different optical activities, lactide is divided into D-lactide, L-lactide and DL-lactide, and the products of its ring-opening polymerization are corresponding It is poly-D-lactic acid, poly-L-lactic acid and poly-DL-lactic acid. Through literature search, it was found that D-lactide and L-lactide were ring-opened in a molar ratio of 1:1 to obtain poly-D, L-lactic acid copolymer and poly-DL-lactic acid synthesized from DL-lactide. shape memory properties, but there is no report on the shape memory properties of poly-L-lactic acid in the existing literature.

Polylactic acid (PLA) was presented in 1966 for degradable surgical implants. Hydrolysis produces lactic acid, a typical intermediate in carbohydrate metabolism. Polyglycolic acid sutures have a foreseeable destruction price, which is consistent with the healing order of natural cells.
Polylactic acid, likewise known as polylactide, is created by ring opening enhancement polymerization of cyclic diester of lactic acid (lactide). Pure DL lactide revealed higher bioabsorption, while pure poly lactide was extra resistant to hydrolysis.
The real time required to completely absorb the poly-L-lactide implant is relatively lengthy and also relies on the polymer purity, handling problems, dental implant website and also physical size of the dental implant.

Polylactic acid Uses

  1. Polylactic acid (PLA) utilizes corn, cassava and various other crops as basic materials, and is obtained by microbial fermentation as well as extraction to get lactic acid, which is then fine-tuned, dehydrated and oligomerized, pyrolyzed and also polymerized. PLA has excellent biodegradability, and can be completely deteriorated by bacteria in the soil within one year after disposal to produce CO2 and also water, and also does not pollute the atmosphere.
  2. Polylactic acid itself is an aliphatic polyester, which has the fundamental features of general polymer products, good machining performance, low contraction rate, and also can be used for most artificial plastics. It is extensively used in the manufacturing of packaging products, disposable tableware, Home home appliance coverings, fibers, 3D consumables, and so on.
  3. Polylactic acid (PLA) powder is a sort of special customized item, which can be utilized in many areas such as aesthetic addition, chemical sector, covering, ceramic firing, and so on. PLA fiber has great air permeability, sweat leaks in the structure, simple molding, simple coloring, anti-bacterial, Anti-ultraviolet and various other attributes, can also be blended with silk.

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Application of Polylactic acid

Experiments have found that poly-L-lactic acid can be deformed below 100 °C, and the deformation recovery temperature is also lower than 100 °C. Therefore, poly-L-lactic acid has shape memory properties below 100 °C, that is, it has shape memory properties and biodegradability. As a medical material, poly-L-lactic acid has advantages unmatched by other materials: because poly-L-lactic acid has shape memory properties, it can be implanted into the body in a compressed form, and heated in the human body to make it self-recovery. The required shape can reduce the wound and relieve the pain of the patient; poly-L-lactic acid is a biodegradable material, which can be degraded into non-toxic products in the human body, so as to avoid the long-term existence of non-degradable implant materials in the body. It also avoids the pain caused by the non-degradable materials that need to be removed by a second operation in some cases. At the same time, poly-L-lactic acid has good biocompatibility: poly-L-lactic acid can be passed through conventional Copolymerization and blending methods can adjust its properties in a wide range to meet different medical needs, which is unmatched by traditional medical shape memory alloys; It has good mechanical properties and slow degradation rate, and is more suitable as a fracture fixation material. Compared with the existing degradable shape memory polymers, poly-L-lactic acid has extremely superior mechanical properties, which is very important for fracture internal fixation and stent applications. The deformation process of poly-L-lactic acid in use is as follows: when the shaped poly-L-lactic acid is heated to the deformation temperature Tf (Tf is higher than the glass transition temperature and lower than 100 ° C), the reversible phase softens, and under the action of external force Deformation into the second shape; under the action of maintaining stress, the poly-L-lactic acid is cooled below the glass transition temperature, the reversible phase enters the glass state, the molecular chain is frozen, and the poly-L-lactic acid is hardened into a deformed shape. Stable solid; when the poly-L-lactic acid with the second shape is heated to the shape recovery temperature (above the Tf temperature and below 100 °C), the reversible phase softens again, and the poly-L-lactic acid returns to the original shape memorized by the stationary phase . The deformation modes mentioned therein can be any one or a mixture of expansion, stretching, compression, bending and torsion.

Poly-L-lactic acid can also be copolymerized with other degradable monomers to form copolymers through ring-opening polymerization. The copolymers of poly-L-lactic acid are mainly copolymers of L-lactide and other lactides, L-lactide and Copolymers of lactones and copolymers of L-lactide and ether segments. The degradation rate of poly-DL-lactic acid is faster than that of poly-L-lactic acid, and the copolymer of the two can adjust its degradation performance; the glass transition temperature of poly-glycolide is lower than that of poly-L-lactic acid, about 45 °C, The glass transition temperature of polyε-caprolactone is very low, about -60 °C, and the copolymerization of poly-L-lactic acid with any monomer or the copolymerization of the three can adjust its shape recovery temperature in a wide range, and at the same time Its mechanical properties and degradation properties can be adjusted to a large extent. At the same time, poly-L-lactic acid can also be blended with other biodegradable polymers to form a blend to adjust its shape recovery temperature, mechanical properties and degradation properties, so as to be more suitable for biomedical applications. Poly-L-lactic acid composite material made by adding biologically active hydroxyapatite particles, dicalcium phosphate, tricalcium phosphate and bioglass to poly-L-lactic acid, wherein hydroxyapatite is the main component of natural bone, It has excellent biological activity and osteoconductivity, and can form a direct osseointegration with bone tissue. Therefore, the poly-L-lactic acid shape memory polymer containing HA particles has great application potential in bone fixation.


Lactic acid – PubChem

Polylactic acid Supplier and Manufacturer

As a polylactic acid supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best polylactic acid raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for polylactic acid and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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