
Polyhexamethylene Biguanide Hydrochloride CAS 32289-58-0 PHMB




Factory Supply Polyhexamethylene Biguanide Hydrochloride CAS 32289-58-0 PHMB with Best Price
- Appearance: Cololrless or light yellow liquid
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Polyhexamethylene Biguanide Hydrochloride Supplier & Manufacturer
Polyhexamethylene Biguanide Hydrochloride: The Complete Guide
- Item 1: Basic Info of Polyhexamethylene Biguanide Hydrochloride
- Item 2: What is Polyhexamethylene Biguanide Hydrochloride?
- Item 3: Polyhexamethylene Biguanide Hydrochloride Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of Polyhexamethylene Biguanide Hydrochloride
- Item 6: Preparation of Polyhexamethylene Biguanide Hydrochloride
- Item 7: Quality Control of Polyhexamethylene Biguanide Hydrochloride
- Item 8: Hot Sale Products
- Item 9: Get Polyhexamethylene Biguanide Hydrochloride Quotation
Polyhexamethylene Biguanide Hydrochloride for Sale
Basic Info of Ammonium alginate
Chemical Name: | Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride |
Other Name: | Polyhexamethylene Biguanide Hydrochloride; Polyhexamethylene Biguanidine HCl; Biguanide PHMB; Poly(hexamethylenebiguanide)hydrochloride; Polyhexanide; PHMB |
CAS: | 32289-58-0 |
EINECS: | 1308068-626-2 |
Type: | Pharmaceutical raw materials; Cosmetic raw materials |
Molecular Formula: | C10H23N5 |
Molecular Weight: | 213.32312 |
storage temp. | Inert atmosphere,Room Temperature |
Brand Name: | Zhishang Chemical |
Provide: | Polyhexamethylene Biguanide Hydrochloride MSDS; Polyhexamethylene Biguanide Hydrochloride COA |
What is Polyhexamethylene Biguanide Hydrochloride?
Polyhexanide (Polyhexamethylene biguanide hydrochloride, PHMB) is a polymer used as a disinfectant and antiseptic. Spelled Polihexanide (inn) for dermatological purposes and sold under the names lavasept, serasept, prontosan and omniside. PHMB has been shown to be resistant to Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Yeast infection albicans, Aspergillus Brazil, Enterococcus as well as Klebsiella pneumoniae.
The average molecular weight of polyhexamethylene biguanide hydrochloride is 1100-1800, the molecular formula is (C8H17N5)n·xHCl, n=12-16. Polyhexamethylene biguanide hydrochloride (PHMB) is a broad-spectrum antibiotic that can kill gram-positive bacteria, gram-negative bacteria, fungi and yeast.
Polyhexamethylene biguanide hydrochloride solution is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria. The virus is adsorbed, thereby inhibiting the division ability of bacteria and viruses, making them lose their reproductive ability, and the film formed by the polymer blocks the respiratory channels of the microorganisms, causing the microorganisms to die quickly.
Polyhexamethylene Biguanide Hydrochloride Uses
- For a long time, polyhexamethylene biguanide hydrochloride PHMB has been widely used in medicine for bactericidal and antiseptic. As a medicinal product, it is used for disinfection of contact lenses, eye drops, and surgical procedures.
- Due to the high tolerance of the eye to PHMB, polyhexamethylene biguanide hydrochloride can be used as an agent for the treatment of acanthamoeba keratitis, prevention and treatment of other eye diseases.
- Polyhexanide is also widely used in cosmetics, personal care products, textiles, food industry, etc.
- Polyhexamethylene biguanide hydrochloride is used as a flocculant, as a bactericide and algaecide in swimming pools and industrial water treatment, as a bactericide in oil production and injection water, and can clean and remove harmful substances on glassware and other hard surfaces.
- Disinfectant. This bactericide is broad-spectrum antibacterial and has the ability to kill gram-positive bacteria, gram-negative bacteria, fungi and yeast, etc. It can be used as a fungicide and is often used in swimming pool bactericides and all-purpose cleaners and disinfectant products.
- Polyhexanide is likewise made use of as a component in some get in touch with lens cleansing products, cosmetics, personal deodorant and also some veterinary items. It is also used to handle clothing (purista), allegedly to prevent unpleasant odors.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
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If you want to buy polyhexamethylene biguanide hydrochloride, pls contact us to get a free quote.
Application of Polyhexamethylene Biguanide Hydrochloride
Its antibacterial effect is mainly by dissolving lipids, changing the permeability of bacterial cell membranes, and causing obstacles to metabolism in bacteria. It is colorless, odorless, non-irritating to the skin, non-toxic and non-corrosive. Therefore, the wet wipes treated with it can achieve rapid disinfection effect without mildew, and the shelf life can be up to two years.
It is suitable for household disinfection, and can be used for sterilization and cleaning of fruits and vegetables; it is used for sterilization and cleaning of various fabrics such as clothing, towels, bed sheets, etc.; Sterilization of the place.
This product can quickly kill harmful bacteria such as Gram-negative bacteria, Floating Vibrio, Vibrio parahaemolyticus, Vibrio alginolyticus in seawater, and is very good for various diseases caused by bacteria in sea cucumber and other aquatic products. preventive and therapeutic effects.
The product is colorless, non-corrosive, and has a long-lasting effect. It can be conveniently used for cleaning and disinfection of skin, wounds, obstetrics and gynecology, and urology. Especially for some medical supplies that cannot be disinfected by high temperature, only a solution with a concentration of 1‰ is required. Soaking or spraying can achieve satisfactory sterilization effect in a short time. The product can also be used for disinfection of air, walls and floors in wards.
The lotion and gel disinfectant made by this product can be used for bacterial, fungal, trichomoniasis, senile and non-specific inflammation, cervicitis and other diseases.
The product is sprayed directly on the hands as a hand sanitizer, which can safely, effectively and conveniently remove pathogenic bacteria on the hands, no water and soap, and can form a colorless layer on the hands. Transparent invisible film, maintain long-term inhibition and sterilization effect.
The product can develop antibacterial textiles, such as towels, underwear, baby clothes, bedding and so on. Simply immerse the textile in the product-specific solution before the final finishing stage. When bacteria fall on the textiles treated by this product, a small amount of water dissolves the active substances contained in them, and kills bacteria quickly. After tests, properly treated textiles are still antibacterial after washing up to 120 times in water.
The product can easily develop various types of sterile and antibacterial sanitary napkins, sanitary pads, baby diapers, etc., which reduces the cost and solves the problem of short validity period of traditional disinfection methods. Because the product can be evenly linked with the fine fibers of the above products, a thin polymer layer of antibacterial agent is formed on the surface, which can maintain the best state after sterilization, and the validity period can be up to two years.
At present, the washing products with disinfection function are generally added with chlorine preparations as disinfection ingredients, which have defects such as corrosiveness to fabrics, fading, short sterilization validity period, and can only be used for white fabrics. The product has the advantages of being soluble in water, non-toxic, colorless, odorless, non-corrosive, non-fading, non-irritating to skin and mucous membranes, and has a long validity period.
The product is used in the sterilization and disinfection of pipelines, containers and other production facilities and floors in the production of beer, beverage and food. It only needs to dilute the product to 10ppm and soak or flush the pipeline to achieve the sterilization effect. If there are no special requirements for filling food cans, the use concentration can be increased to 250ppm to achieve the effect of quickly and completely killing bacteria.
Preparation of Polyhexamethylene Biguanide Hydrochloride
To a three-necked flask equipped with a thermometer and a stirring rotor, ethanol was added as a solvent to weigh 1,6-hexanediamine, and hydrochloric acid was added dropwise with stirring, and the reaction was exothermic. Control the dropping rate, keep the temperature below 28°C during the dropwise addition until the pH value of the solution reaches 5, continue the reaction for 1 hour after the dropwise addition is completed to ensure that the reaction is complete, then reduce the temperature to 0°C, filter, and filter the obtained filter cake drying. Then pure hexamethylenediamine hydrochloride is obtained.
Weigh a certain amount of dicyandiamide and hexamethylenediamine hydrochloride, the molar ratio of the two is 1:1.1, add a certain amount of n-butanol as a solvent, stir and heat under reflux, the polymerization reaction temperature is 170 ℃, constant temperature After 12 hours, n-butanol was distilled off to obtain the product.
Reference
- Polyhexanide – WikiPedia
- “Classification and Labelling of PHMB”. European Chemicals Agency.
- Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride – ChemicalBook
- Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride – PubChem
Polyhexamethylene Biguanide Hydrochloride Supplier and Manufacturer
As a polyhexamethylene biguanide hydrochloride supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best polyhexamethylene biguanide hydrochloride raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for polyhexamethylene biguanide hydrochloride and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Polyhexamethylene Biguanide Hydrochloride


