SHANDONG ZHISHANG CHEMICAL CO.LTD.

Plant extract CAS NO 486-66-8 Daidzein

Basic Info

Model No.: X-CAS 486-66-8

Certification: ISO, FDA, HACCP

Assay Method: HPLC-MS, GPC, HPLC

Application Form: Capsule

Application: Food, Health Care Products, Medicine

State: Crystal

Extract Source: Other

CAS No.:: 486-66-8

MF:: C15H10O4

Grade: Synthetic Perfume, Chemicals

MW: 254.23700

Appearance: Yellow Crystalline Solid

Bp:: 512.8ºC At 760 MmHg

FP:: 201.2ºC

Additional Info

Packaging:  in 25kg drum

Productivity: 10000kg per month

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 486-66-8

Port: Shanghai,Tianjin,Qingdao

Product Description

CAS NO 486-66-8 Daidzein

    The binding reaction between daidzein and human serum albumin (HSA) was studied by fluorescence quenching spectroscopy, synchronous fluorescence spectroscopy and UV-Vis absorption spectroscopy. Daidzein has a strong fluorescence quenching effect on human serum albumin, the quenching mechanism belongs to static quenching, and intramolecular non-radiative energy transfer occurs. Using the Stern-Volmer equation to process the experimental data, the binding constants KA between daidzein and HSA were 0.34 × 104 (23 ℃), 1.10 × 104 (30 ℃) and 4.36 × 104 L · mol – 1 (40 ° C). According to F? Rster non-radiative energy transfer theory, the binding distance between daidzein and HSA was found to be 1.50 nm (23 ℃), 1.46 nm (30 ℃) and 1.42 nm (40 ℃) . By calculating the corresponding thermodynamic parameters, we can see daidzein interaction with human serum albumin is a spontaneous process of Gibbs free energy reduction, and the main force between the two types of hydrophobic force, while using synchronous fluorescence Spectra were used to investigate the effect of daidzein on the conformation of HSA.
Experiments show that daidzein fluorescence quenching of HSA belongs to the static quenching mechanism, and intramolecular non-radiative energy transfer occurs; the two mainly by the hydrophobic force combination, the binding site close to the Trp residues in HSA, After binding, the polarity of the microenvironment in which the Trp residues are located slightly decreases, resulting in a change in the conformation of HSA.

Storage: 

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.

Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the Raw Material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.

Leave a Comment

Your email address will not be published.