Piroctone Olamine CAS 68890-66-4

Factory Supply Piroctone Olamine CAS 68890-66-4 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Piroctone Olamine Supplier & Manufacturer

Basic Info

What is Piroctone Olamine?

Pyridone olamine salt (P.O.) has excellent anti-dandruff and anti-itch effect, unique anti-dandruff mechanism, excellent solubility and compoundability, safe, non-toxic, non-irritating, and is mainly used in hair care products. So far, it is the only anti-dandruff and anti-itch agent that can be used in leave-in hair products. P.O. is very effective in relieving itching, and also has bactericidal and deodorizing functions, so it is used in bath liquids and has achieved good results. P.O. has a broad-spectrum killing effect on fungi and mold, and has a good therapeutic effect on athlete’s foot and tinea manuum. It can be used as a preservative in cosmetics, as a fungicide in soap, and has thickening properties. Therefore, P.O. is a multi-functional anti-dandruff anti-itch fungicide, which is widely used in shampoo and hair care products, body wash, cosmetics and washing products.

In the related art, the preparation process of pyridone ethanolamine salt (1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone ethanolamine salt) undergoes Friedel-Crafts acylation reaction, ring closure reaction, hydroxylamination reaction, and salt-forming reaction to obtain pyridone ethanolamine salt. Among them, in the Friedel-Crafts acylation reaction, anhydrous aluminum chloride is generally used as a catalyst to promote the reaction. Although anhydrous aluminum chloride has a good catalytic effect, in the actual production of pyridone ethanolamine salt, there is no The use of aluminum chloride hydrate is not only difficult to recycle, but also produces a large amount of waste water, which is very difficult to deal with, and the supported catalyst has the advantage of being easy to recycle. Therefore, how to realize the application of the supported catalyst in the Friedel-Crafts acylation reaction has become a problem for pyridine. Problems to be solved urgently in the production process of ketoethanolamine salt.

Piroctone Olamine Uses

Piroctone olamine salt has a broad-spectrum killing impact on fungi and also mold and mildews, and also has a great restorative effect on professional athlete’s foot and tinea manuum. It can be utilized as a chemical in cosmetics, as a fungicide in soap, and has thickening residential properties. Consequently, piroctone olamine is a multifunctional anti-dandruff antipruritic bactericide, which is commonly used in hair shampoo and hair treatment items, body wash, cosmetics, and also cleaning items.

The distinct performance of piroctone olamine salt is mostly materialized in:

  1. The anti-dandruff and anti-itch impact is better than comparable items.
  2. Outstanding solubility as well as intensifying performance, no rainfall or stratification will certainly happen when mixed with aesthetic resources.
  3. The anti-dandruff mechanism is one-of-a-kind, the inflammation is very low, as well as it will certainly not trigger hair loss or hair damage. It is more secure than similar anti-dandruff and also anti-itch products.

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Application of Piroctone Olamine

  • Application one
    CN202010405168.6 discloses a plant anti-dandruff shampoo, including deionized water, sodium laureth sulfate, cocamide MEA, sodium lauroamphoacetate, cocamidopropyl betaine, polydimethyl Polysiloxane, Guar Hydroxypropyltrimonium Chloride, Behenamidopropyldimethylamine, Polyquaternium-10, Amodimethicone, C12-15 Alkanol Ether-3, Allantoin, Zinc Pyrithione, Oxypyrone, Carbomer, C12-13 Alcohol Lactate, Disodium EDTA, DMDM Hydantoin, Cathone, Potassium Hydroxide, Zinc Chloride, Sodium Chloride, Magnolia Bark Bark Extract, Sophora Root Extract, Ginseng Root Extract, Aloe Vera Extract, Motherwort Extract, Golden Chamomile Extract, Calendula Flower Extract and Parfum. The prepared plant anti-dandruff shampoo has good anti-dandruff effect, gently cleans the scalp and hair, and deeply revitalizes the hair roots. Multiple plant essences can improve scalp problems from the root.

  • Application two
    CN201911398607.9 discloses eucalyptus oil dandruff-free shampoo, 10-20 parts of sodium laureth sulfate, 10-20 parts of cocamidopropyl betaine, 5-8 parts of lauroyl amphoteric di Disodium acetate, 5-8 parts of cocamide EDA, 6-10 parts of polyquaternium-10, 1-3 parts of essence, 1-3 parts of citric acid, 0.5-1 part of panthenol, 2-5 parts of hydroxypyrrole Ketone, 1-3 parts of butanediol, 3-5 parts of peppermint extract, 3-5 parts of blue eucalyptus, 1-2 parts of methylisothiazolinone and 50-65 parts of soft water; compared with the prior art, this The beneficial effects of the invention are: the invention can mildly clean the scalp and hair, prevent or remove dandruff, regulate unbalanced scalp, and help keep the scalp healthy.

Preparation of Piroctone Olamine

The supported catalyst includes an active component and a carrier, the carrier is silica gel, the purity of the silica gel is ≥ 80%, and is selected from the catalyst silica gel 123 of Qingdao Hailang Silica Gel Desiccant Co., Ltd. Mace, anhydrous lithium perchlorate, and the weight loading of anhydrous aluminum chloride on the carrier is 7wt%; the weight loading of anhydrous chloride on the carrier is 5wt%; anhydrous lithium perchlorate on the carrier The weight loading on is 0.8wt%.

The supported catalyst is prepared by the following method:

  • Pretreatment of silica gel
    Add silica gel into ethanol, make the silica gel completely immersed in ethanol, stir and mix evenly, heat up to 30°C, keep warm for 4 hours, filter, then wash with ethanol twice, then add into hydrochloric acid solution, completely immerse the silica gel in hydrochloric acid solution In the solution, the mass concentration of hydrochloric acid solution is 3%, stir and mix evenly, heat up to 60°C, heat preservation treatment for 8h, filter, and then wash with water for 3 times, then add ethanol to completely immerse the silica gel in ethanol, stir and mix Evenly, heat up to 30°C, keep warm for 40min, filter, then wash with ethanol for 3 times, put in a vacuum environment of 70°C, and dry for 12h to obtain the pretreated silica gel.
  • Active ingredient blend
    Mix anhydrous aluminum chloride, anhydrous aluminum chloride, and anhydrous lithium perchlorate evenly to obtain mixture a.
  • Active ingredient loading
    Under the protection of nitrogen, add pretreated silica gel in 100g carbon tetrachloride, the weight ratio of carbon tetrachloride and silica gel is 4:1, stir and mix evenly, then add compound a, continue to stir, and heat up to 40°C, heat-preserved and refluxed for 50h, filtered, washed 3 times with carbon tetrachloride, then washed 2 times with ethanol, placed in a vacuum environment at 60°C, and dried for 16h to obtain a supported catalyst.

Wherein, the nitrogen gas is dehumidified with a desiccant before use to remove moisture in the nitrogen gas, and the desiccant is anhydrous calcium chloride.


  1. Piroctone olamine – WikiPedia
  2. CN202010405168.6 A plant anti-dandruff shampoo and its preparation method
  3. CN201911398607.9 Eucalyptus oil dandruff-free shampoo and its preparation method

Piroctone Olamine Supplier and Manufacturer

As a piroctone olamine supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best piroctone olamine raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for piroctone olamine and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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