Phenylethyl Resorcinol CAS 85-27-8

1. Mix the water 75%wt~100%wt, collagen extract 1%wt~5.0%wt, hydrolyzed beta glucan 1%wt~3.0%wt, glycerol 1%wt~2.0%wt, butylene glycol 1%wt~2.0%wt, betaine 0.1%wt~1.0%wt, allantoin 0.1%wt~0.2%wt, cylindrine 0.1%wt~0.2%wt were poured into the reaction kettle and heated to a temperature of 85 Celsius, that is A phase.
2. The described phenethyl resorcinol 1%wt～4.0%wt, dioctyl carbonate 1%wt～4.0%wt, squalane 1.0%wt～3.0%wt, stearyl alcohol 1%wt～ 3.0%wt, steareth-21%wt~2.0%wt, steareth-211%wt~2.0%wt, tocopherol 0.1%wt~0.5%wt, bisabolol 0.1%wt~ 0.2%wt is poured into the reaction kettle and heated to a temperature of 85 degrees Celsius, which is the B phase.
3. Pour the imidazolidinyl urea 0.1%wt～0.2%wt, essence 0.1%wt into the reaction kettle, stir evenly, and be phase C.
4. Mix phase A and phase B evenly, homogenize for 10 minutes, then cool, add phase C at a temperature of about 30 degrees Celsius, stir evenly, and discharge to obtain freckle cream.

4.0% polyoxyethylene sorbitan fatty acid ester, 1.0% polyoxyethylene castor oil, 25.0% 1,3-propylene glycol, 3.0% hydrogenated polydecene, 0.1% phenethyl resorcinol, 5.0% papaya Protease and 0.4% phloretin were dissolved by stirring in a water bath at 40°C to obtain an oil phase, which was used for later use; 0.1% heparin sodium, 0.1% vitamin C ethyl ether, 0.05% allantoin, 0.05% carnosine, 5.0% glycerin and 59.29% water, stirring and dissolving in a water bath at 40°C to obtain an aqueous phase for use;

After the oil phase and the water phase are obtained, the oil phase is added dropwise to the water phase at a rate of 1 drop/second under the condition of a 40°C water bath, and the stirring rate is controlled to be 15 rpm during the dropwise addition. Shear and emulsify for 1 min to prepare a micron-sized dispersion; the micron-sized dispersion is subjected to high-pressure homogenization treatment under the condition of a pressure of 1200 bar, and circulated once to obtain a co-transported nano-composition of phenethyl resorcinol. The particle size of the co-transported nano-composition of phenethyl resorcinol was detected, and it was found that the particle size of the co-transported nano-composition of phenethyl resorcinol was 50.2 nm.

Solving the problems in the prior art that high-concentration phenethyl resorcinol is easy to cause allergies, and the cosmetic whitening effect of conventional concentration phenethyl resorcinol is not significant, and a co-transportation of phenethyl resorcinol is provided. The nano-composite, phenethyl resorcinol has high drug loading, no significant irritation to the skin, multi-target and multi-mechanism whitening and anti-oxidation, good skin permeability, high retention, and good whitening effect.