
Phenylethyl Resorcinol CAS 85-27-8



Factory Supply Phenylethyl Resorcinol CAS 85-27-8 with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Phenylethyl Resorcinol Supplier & Manufacturer
Phenylethyl Resorcinol: The Complete Guide
- Item 1: Basic Info of Phenylethyl Resorcinol
- Item 2: What is Phenylethyl Resorcinol?
- Item 3: Phenylethyl Resorcinol Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of Phenylethyl Resorcinol
- Item 6: Preparation of Phenylethyl Resorcinol
- Item 7: Quality Control of Phenylethyl Resorcinol
- Item 8: Hot Sale Products
- Item 9: Get Phenylethyl Resorcinol Quotation
Phenylethyl Resorcinol for Sale
Basic Info of Phenylethyl Resorcinol
Chemical Name: | Phenylethyl Resorcinol |
Other Name: | 4-(alpha-Methylbenzyl)resorcinol; Nanoactive Phenylethyl Resorcinol |
CAS: | 85-27-8 |
EINECS: | 480-070-0 |
Type: | Food additives; Pharmaceutical raw materials; Organic raw materials; Cosmetic raw materials; Pharmaceutical intermediates; Synthetic material intermediates |
Molecular Formula: | C14H14O2 |
Molecular Weight: | 214.26 |
Melting point | 78-79℃ |
Boiling point | 244°C/12mmHg(lit.) |
density | 1.171 |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Solid |
pka | 9.77±0.40(Predicted) |
color | Light Beige to Pale Brown |
Brand Name: | Zhishang Chemical |
Provide: | Phenylethyl Resorcinol MSDS; Phenylethyl Resorcinol COA |
What is Phenylethyl Resorcinol?
Phenylethyl Resorcinol (Phenylethyl Resorcinol), molecular formula C14H14O2, full chemical name 4-(1-phenethyl)-1,3-benzenediol, is a white crystalline strong with low smell. Soluble in ethanol, propylene glycol, butanediol, pentanediol, as well as the solubility in water is 265mg/L at 25 ° C. Phenethylresorcinol is an efficient bleaching component developed by Symrise. It has a solid antioxidant effect and highly hinders the task of tyrosinase, thus lowering the manufacturing of melanin. Skin tests revealed that 0.5% 377 was extra efficient than 1% kojic acid in the lack of light direct exposure. In 2012, the China Fda (SFDA) has actually accepted phenethyl resorcinol as a cosmetic raw material for usage in cosmetics.
Given that phenethyl resorcinol is a by-product of fat-soluble resorcinol, it is insoluble in water as well as unstable when subjected to light. Under the problem of light, phenethyl resorcinol can become pink shade such as quinones. compound. These issues result in considerably minimized bioavailability of phenethylresorcinol. For that reason, it is required to take certain procedures to enhance its photostability, therefore improving its bioavailability as well as the legitimacy period of cosmetics.
The chemical name of phenylethyl resorcinol is 4-(1-phenylethyl)-1,3-benzenediol, which is an useful active ingredient with exceptional whitening result. It mainly achieves lightening by inhibiting the task of tyrosinase. Purpose. Existing studies have actually revealed that phenethyl resorcinol can properly whiten the skin when the dosage is greater than 0.5%, and can additionally effectively stand up to oxidation as well as crease at the same time. Nevertheless, high concentrations of phenylethyl resorcinol can trigger skin allergic reactions when made use of in cosmetics. The limit of use in cosmetics is 0.5%. The trouble of very easy allergic reaction makes it difficult to utilize phenylethyl resorcinol in large doses. A better bleaching effect can not be achieved.
Phenylethyl Resorcinol Uses
- The chemical name of phenylethyl resorcinol is 4-(1-phenylethyl)-1,3-benzenediol, which is a practical component with superb bleaching impact. It mostly attains bleaching by hindering the task of tyrosinase. Objective. Existing researches have actually shown that phenethyl resorcinol can successfully bleach the skin when the dosage is greater than 0.5%, and also can additionally properly resist oxidation and also wrinkle at the same time. Nonetheless, high focus of phenylethyl resorcinol can trigger skin allergies when utilized in cosmetics. The limit of use in cosmetics is 0.5%. The trouble of very easy allergy makes it hard to make use of phenylethyl resorcinol in large dosages. A much better bleaching impact can not be attained.
- 4-(1-Phenoxyl)-1,3-benzenediol is a new active ingredient of skin lightening agent with high efficiency.
- Phenylethyl resorcinol has a good effect of inhibiting melanin. At present, there are two main methods for inhibiting melanin production, namely inhibiting the activity of tyrosinase and controlling the oxidation of dopa. Phenylethyl resorcinol is a One of the reported tyrosinase inhibitors with the highest activity, the key factor is that it has a bisphenol structure, which can play a competitive inhibitory role on tyrosinase. In recent years, more and more big brand cosmetics have gradually Replaced this ingredient.
- Phenylethyl resorcinol is often used as a brightening agent in cosmetics, but because the product has a certain irritant effect on the skin, the dosage of the product is limited, and the manufacturer recommends that the dosage is usually 0.1%-1.0% , the domestic limit of 377 concentration, the highest is 0.5%.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
- WhatsApp: +86 176 5311 3209
- WeChat: Zhishang17653113209
- Skype: +86 176 5311 3209
If you want to buy phenylethyl resorcinol, pls contact us to get a free quote.
Application of Phenylethyl Resorcinol
- Mix the water 75%wt~100%wt, collagen extract 1%wt~5.0%wt, hydrolyzed beta glucan 1%wt~3.0%wt, glycerol 1%wt~2.0%wt, butylene glycol 1%wt~2.0%wt, betaine 0.1%wt~1.0%wt, allantoin 0.1%wt~0.2%wt, cylindrine 0.1%wt~0.2%wt were poured into the reaction kettle and heated to a temperature of 85 Celsius, that is A phase.
- The described phenethyl resorcinol 1%wt~4.0%wt, dioctyl carbonate 1%wt~4.0%wt, squalane 1.0%wt~3.0%wt, stearyl alcohol 1%wt~ 3.0%wt, steareth-21%wt~2.0%wt, steareth-211%wt~2.0%wt, tocopherol 0.1%wt~0.5%wt, bisabolol 0.1%wt~ 0.2%wt is poured into the reaction kettle and heated to a temperature of 85 degrees Celsius, which is the B phase.
- Pour the imidazolidinyl urea 0.1%wt~0.2%wt, essence 0.1%wt into the reaction kettle, stir evenly, and be phase C.
- Mix phase A and phase B evenly, homogenize for 10 minutes, then cool, add phase C at a temperature of about 30 degrees Celsius, stir evenly, and discharge to obtain freckle cream.
4.0% polyoxyethylene sorbitan fatty acid ester, 1.0% polyoxyethylene castor oil, 25.0% 1,3-propylene glycol, 3.0% hydrogenated polydecene, 0.1% phenethyl resorcinol, 5.0% papaya Protease and 0.4% phloretin were dissolved by stirring in a water bath at 40°C to obtain an oil phase, which was used for later use; 0.1% heparin sodium, 0.1% vitamin C ethyl ether, 0.05% allantoin, 0.05% carnosine, 5.0% glycerin and 59.29% water, stirring and dissolving in a water bath at 40°C to obtain an aqueous phase for use;
After the oil phase and the water phase are obtained, the oil phase is added dropwise to the water phase at a rate of 1 drop/second under the condition of a 40°C water bath, and the stirring rate is controlled to be 15 rpm during the dropwise addition. Shear and emulsify for 1 min to prepare a micron-sized dispersion; the micron-sized dispersion is subjected to high-pressure homogenization treatment under the condition of a pressure of 1200 bar, and circulated once to obtain a co-transported nano-composition of phenethyl resorcinol. The particle size of the co-transported nano-composition of phenethyl resorcinol was detected, and it was found that the particle size of the co-transported nano-composition of phenethyl resorcinol was 50.2 nm.
Solving the problems in the prior art that high-concentration phenethyl resorcinol is easy to cause allergies, and the cosmetic whitening effect of conventional concentration phenethyl resorcinol is not significant, and a co-transportation of phenethyl resorcinol is provided. The nano-composite, phenethyl resorcinol has high drug loading, no significant irritation to the skin, multi-target and multi-mechanism whitening and anti-oxidation, good skin permeability, high retention, and good whitening effect.
Preparation of Phenylethyl Resorcinol
0.2 mol of 2,4-diacetoxystyrene was put into a three-necked flask with stirring, 4 mol of benzene was placed in, and also 0.001 mol of p-toluenesulfonic acid was placed in, the temperature level was increased to 80 ° C. as well as refluxed, as well as the temperature was kept for 5 hrs. After that the temperature level was reduced to 50 ° C., 4 mol of methanol was added, the temperature level was raised to 64 ° C. as well as refluxed, and also the temperature was kept for 1 hr. Then, climatic purification was performed to boil down off the solvent. The recurring material in the flask was recrystallized to acquire 32 g of phenethyl resorcinol, which was detected by fluid chromatography, as well as the material was 99.5% and the return was 80%.
Reference
- Phenylethyl resorcinol – PubChem
- Zhao Shizhi, Fang Qingqiu, Ye Jun, Yang Shan, & Wang Lei. (2014). Preparation and stability analysis of phenethylresorcinol nanostructured lipid carriers. Food and Drugs, 16(6), 384-388.
Phenylethyl Resorcinol Supplier and Manufacturer
As a phenylethyl resorcinol supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best phenylethyl resorcinol raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for phenylethyl resorcinol and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Phenylethyl Resorcinol

