
Permethrin CAS 52645-53-1



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- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Permethrin Supplier & Manufacturer
Permethrin: The Complete Guide
Permethrin for Sale
Basic Info of Permethrin
Chemical Name: | Permethrin |
Other Name: | Permethrine; Permethrin cas 52645-53-1; (3-Phenylchlorobenzyl)methylcis,trans(±)-3(-2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate |
CAS: | 52645-53-1 |
EINECS: | 258-067-9 |
Type: | Feed additives; Pharmaceutical raw materials; Pesticides; Flavors and Fragrances |
Molecular Formula: | C21H20Cl2O3 |
Molecular Weight: | 391.29 |
Melting point | 34-35°C |
Boiling point | bp0.05 220° |
density | 1.19 |
vapor pressure | 7×10-5 Pa (20 °C) |
refractive index | 1.6500 (estimate) |
Fp | 10 °C |
storage temp. | 0-6°C |
form | neat |
Water Solubility | insoluble |
Stability: | Stable. Incompatible with strong oxidising agents. |
Brand Name: | Zhishang Chemical |
Provide: | Permethrin MSDS; Permethrin COA |
What is Permethrin?
Permethrin is a pyrethroid insecticide with little toxicity to mammals. It has been marketed as a tick repellent. Permethrin is the only synthetic pyrethroid used to treat head lice worldwide. Spray formulations are the most widely available form. Once applied to clothes, it is stable over several washing cycles. It is also suitable for handling sleeping bags, tents and fabrics for insect screening. Liquid concentrates have been used to impregnate fabrics over the service life of clothing. Permethrin is particularly helpful in preventing tick and chigger bites. These reptile arthropods must pass through the treated fabric, and the flying insects are often attracted directly to the exposed skin.
Permethrin is 3 – (2,2-dichloroethylene) – 2,2-dimethylcyclopropanecarboxylic acid (3-phenoxyphenyl) methyl ester or 3 – (phenoxyphenyl) methyl (±) – CIS and trans-3 – (2,2-dichloroethylene) – 2,2-dimethylcyclopropanecarboxylic acid salt (Nix). This synthetic pyrethroid compound is chemically more stable than most natural pyrethroids and is at least as effective as insecticides. Among the four isomers, 1 (R), trans and 1 (R), cis isomers are mainly responsible for insecticidal activity. The commercially available product is a mixture of 60% trans and 40% CIs racemic isomers. It exists in the form of colorless to yellowish low melting point crystals or yellowish liquid, insoluble in water, but soluble in most organic solvents.
Permethrin is lethal to lice, ticks, mites and fleas. It acts on the nerve cell membrane of parasites to disrupt the conduction of sodium channels. Used as a acaricide for treating head lice. More than 99% of cases can be cured by applying 1% solution once. The most common side effect was pruritus, which occurred in about 6% of the subjects.
Permethrin Uses
- Permethrin is an artificial pyrethroid, which is active versus lice, ticks, mites as well as fleas. It acts on the membrane of nerve cells, delaying repolarization and triggering paralysis.
- Classified permethrin (p288500). Artificial pyrethroid insecticides are more stable to light, at the very least as energetic as natural pyrethroids, as well as have low poisoning to mammals.
- Permethrin is made use of to deal with scabies and scabies (scabies) infection; Anti hyperlipidemia; Cholesterol chelating agent.
- This item is a high-efficiency as well as low-toxicity pesticide, which is utilized to regulate various crop parasites such as cotton, rice, veggies, fruit trees and also tea trees, as well as sanitary pests as well as animals parasites.
- Permethrin has strong get in touch with murder as well as stomach poisoning impacts, and has the characteristics of solid knockdown force and fast insecticidal speed. It is much more steady to light, and also under the same problems of use, the growth of resistance to pests is also slower, as well as it is highly effective for lepidopteran larvae. Can be utilized for veggies, tea, fruit trees, cotton as well as other crops to control cabbage caterpillars, aphids, cotton bollworm, cotton bollworm, cotton aphid, environment-friendly ligus, yellow-striped flea beetle, peach little heartworm, citrus leaf miner, 28 stars Ladybugs, tea inchworms, tea caterpillars, tea fine moths and various other bugs also have excellent effects on insects, flies, fleas, cockroaches, lice and also various other hygienic bugs.
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Application of Permethrin
- In agriculture, safeguard crops (the downside is that it is lethal to bees).
- In farming, eliminating livestock bloodsuckers.
- For commercial and also household pest control.
- In the textile market, avoid the pests of woolen fabrics.
- In the field of aviation, the Globe Health And Wellness Company, the international health and wellness regulations and the International Civil Aviation Organization require that showing up aircraft be disinfected prior to boarding, taking off, landing or disembarking in some countries. It is advised to use permethrin based items only prior to boarding. It is suggested to make use of aircraft pesticide based upon d-permethrin (1R trans permethrin) before takeoff (after boarding), on top of descent or upon arrival.
- As an individual protective measure, permethrin is related to garments. It is a material impregnating representative, especially for insect internet and outside wear. Although permethrin might be marketed as an insect repellent, it does not protect against bugs from landing. Rather, it acts to disarm or eliminate insects before they attack.
- In pet flea avoidance collar or treatment (secure for dogs, yet except cats).
- In wood treatment.
Permethrin can be used in your area as cream or lotion. It is suitable for the treatment and avoidance of head lice revealed individuals and also the treatment of scabies.
Treatment of scabies: adults and youngsters over 2 months of age were instructed to use cream to the whole body from head to foot. Clean off the cream after 8-14 hrs. In general, one treatment is alleviative.
Utilized to deal with head lice: apply to hair, scalp and neck after shampooing. Mean 10 minutes and rinse. Stay clear of contact with eyes.
In agriculture, permethrin is primarily utilized for cotton, wheat, corn and alfalfa plants. Its usage is questionable since as a broad-spectrum chemical, it kills individuals indiscriminately. In addition to the expected parasites, it can additionally hurt helpful bugs, including , as well as cats as well as aquatic microorganisms.
Permethrin eliminates ticks and insects when exposed to dealt with clothing. A technique of decreasing the variety of deer ticks by treating rodent vectors includes loading naturally degradable cardboard tubes with permethrin treated cotton. Computer mice accumulate cotton to line their nests. Permethrin on cotton can kill any immature tick that eats computer mice.
Permethrin is used in exotic locations to avoid mosquito birthed conditions such as dengue fever and jungle fever. Mosquito webs made use of to cover beds can be treated with permethrin solution. This enhances the effectiveness of the mosquito internet by killing parasitic pests before they can discover gaps or holes in the net. Workers working in jungle fever native areas might be advised to treat their clothes with permethrin too.
Permethrin is the most generally used insecticide in the world, which is used to safeguard wool from sexy bugs (such as tineola bissellella).
In order to better protect soldiers from the danger and also nuisance of insect bites, the British and also United States forces are dealing with all brand-new attires with permethrin.
Permethrin (and other long-acting pyrethroids) works for numerous months, particularly when utilized indoors. International research reports that permethrin can still be detected in indoor dirt, fine dirt and also indoor surface area also after a number of years of use. After 3 months, the degradation rate had to do with 10% under indoor problems.
Unlike the most usual transformative system of insecticide resistance – choice of pre-existing low-frequency alleles – in Aedes aegypti, permethrin resistance is generated via an usual mechanism of pyrethroids and DDT, i.e. “tear down resistance” (KDR) mutations. Garc í an et alia located in 2009 that the kdr allele has quickly spread to the entire of Mexico and also has just recently controlled there.
Preparation of Permethrin
Synthesis of 1,1,1-trichloro-4-methyl-4-penten-2-ol with trichloroacetaldehyde and isobutene, and 1,1,1-trichloro-4-methyl is obtained after transposition -3-Penten-2-ol, and then condensed and rearranged with triethyl orthoacetate to obtain 3,3-dimethyl-4,6,6-trichloro-5-hexenoic acid ethyl ester, which was further added to ethanol Under the action of sodium, it is cyclized to 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane carboxyl ester ethyl ester, which is saponified to form sodium salt, and then mixed with 3-phenoxybenzyl chloride. Dichlorphenidate was obtained by reacting with triethylamine. The raw materials and intermediates of this method are easier to obtain, and the operating conditions are stricter in the process. The product content is generally 60-80%, and it is processed into 3.2% or 10% EC and 0.25% powder for use.
Reference
- Permethrin – WikiPedia
- Permethrin – PubChem
Permethrin Supplier and Manufacturer
As a permethrin supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best permethrin raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for permethrin and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Quality Control of Permethrin

