Permethrin CAS 52645-53-1

Factory Supply Permethrin CAS 52645-53-1 with Best Price

  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Permethrin Suppiler
52645-53-1

Basic Info of Permethrin

What is Permethrin?

Permethrin is a pyrethroid insecticide with little toxicity to mammals. It has been marketed as a tick repellent. Permethrin is the only synthetic pyrethroid used to treat head lice worldwide. Spray formulations are the most widely available form. Once applied to clothes, it is stable over several washing cycles. It is also suitable for handling sleeping bags, tents and fabrics for insect screening. Liquid concentrates have been used to impregnate fabrics over the service life of clothing. Permethrin is particularly helpful in preventing tick and chigger bites. These reptile arthropods must pass through the treated fabric, and the flying insects are often attracted directly to the exposed skin.

Permethrin is 3 – (2,2-dichloroethylene) – 2,2-dimethylcyclopropanecarboxylic acid (3-phenoxyphenyl) methyl ester or 3 – (phenoxyphenyl) methyl (±) – CIS and trans-3 – (2,2-dichloroethylene) – 2,2-dimethylcyclopropanecarboxylic acid salt (Nix). This synthetic pyrethroid compound is chemically more stable than most natural pyrethroids and is at least as effective as insecticides. Among the four isomers, 1 (R), trans and 1 (R), cis isomers are mainly responsible for insecticidal activity. The commercially available product is a mixture of 60% trans and 40% CIs racemic isomers. It exists in the form of colorless to yellowish low melting point crystals or yellowish liquid, insoluble in water, but soluble in most organic solvents.

Permethrin is lethal to lice, ticks, mites and fleas. It acts on the nerve cell membrane of parasites to disrupt the conduction of sodium channels. Used as a acaricide for treating head lice. More than 99% of cases can be cured by applying 1% solution once. The most common side effect was pruritus, which occurred in about 6% of the subjects.

Permethrin Uses

  1. Permethrin is an artificial pyrethroid, which is active versus lice, ticks, mites as well as fleas. It acts on the membrane of nerve cells, delaying repolarization and triggering paralysis.
  2. Classified permethrin (p288500). Artificial pyrethroid insecticides are more stable to light, at the very least as energetic as natural pyrethroids, as well as have low poisoning to mammals.
  3. Permethrin is made use of to deal with scabies and scabies (scabies) infection; Anti hyperlipidemia; Cholesterol chelating agent.
  4. This item is a high-efficiency as well as low-toxicity pesticide, which is utilized to regulate various crop parasites such as cotton, rice, veggies, fruit trees and also tea trees, as well as sanitary pests as well as animals parasites.
  5. Permethrin has strong get in touch with murder as well as stomach poisoning impacts, and has the characteristics of solid knockdown force and fast insecticidal speed. It is much more steady to light, and also under the same problems of use, the growth of resistance to pests is also slower, as well as it is highly effective for lepidopteran larvae. Can be utilized for veggies, tea, fruit trees, cotton as well as other crops to control cabbage caterpillars, aphids, cotton bollworm, cotton bollworm, cotton aphid, environment-friendly ligus, yellow-striped flea beetle, peach little heartworm, citrus leaf miner, 28 stars Ladybugs, tea inchworms, tea caterpillars, tea fine moths and various other bugs also have excellent effects on insects, flies, fleas, cockroaches, lice and also various other hygienic bugs.

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Application of Permethrin

Preparation of Permethrin

Synthesis of 1,1,1-trichloro-4-methyl-4-penten-2-ol with trichloroacetaldehyde and isobutene, and 1,1,1-trichloro-4-methyl is obtained after transposition -3-Penten-2-ol, and then condensed and rearranged with triethyl orthoacetate to obtain 3,3-dimethyl-4,6,6-trichloro-5-hexenoic acid ethyl ester, which was further added to ethanol Under the action of sodium, it is cyclized to 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane carboxyl ester ethyl ester, which is saponified to form sodium salt, and then mixed with 3-phenoxybenzyl chloride. Dichlorphenidate was obtained by reacting with triethylamine. The raw materials and intermediates of this method are easier to obtain, and the operating conditions are stricter in the process. The product content is generally 60-80%, and it is processed into 3.2% or 10% EC and 0.25% powder for use.

Reference

  1. Permethrin – WikiPedia
  2. Permethrin – PubChem

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