
Oxalyl Chloride CAS 79-37-8



Factory Supply Oxalyl Chloride CAS 79-37-8 with Best Price
- Appearance: Colorless liquid
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Oxalyl Chloride Supplier & Manufacturer
Oxalyl Chloride: The Complete Guide
- Item 1: Basic Info
- Item 2: What is Oxalyl Chloride?
- Item 3: Oxalyl Chloride Uses
- Item 4: The Manager has Something to Say
- Item 5: Reaction Mechanism of Oxalyl Chloride
- Item 6: Resolve Resolution of Oxalyl Chloride
- Item 7: Quality Control
- Item 8: Hot Sale Products
- Item 9: Get Oxalyl Chloride Quotation
Oxalyl Chloride for Sale
Basic Info
Chemical Name: | Oxalyl Chloride |
Other Name: | Ethyl oxalyl chloride; Methyl oxalyl chloride |
CAS: | 79-37-8 |
EINECS: | 201-200-2 |
Type: | Organic raw materials; Pesticide intermediates; Material intermediates and auxiliaries |
Molecular Formula: | C2Cl2O2 |
Molecular Weight: | 79-37-8 |
Melting point | -10–8 °C (lit.) |
Boiling point | 62-65 °C (lit.) |
density | 1.5 g/mL at 20 °C (lit.) |
vapor density | 4.4 (vs air) |
vapor pressure | 150 mm Hg ( 20 °C) |
refractive index | n20/D 1.429(lit.) |
Fp | 176-178°C |
storage temp. | Store Cold |
form | Liquid |
color | APHA: 0-150 |
Odor | penetrating odor |
Water Solubility | reacts |
Sensitive | Moisture Sensitive |
Decomposition | 176-178 ºC |
Exposure limits | ACGIH: TWA 50 ppm |
Stability: | Stable. Incompatible with bases, alcohols, steel, oxidizing agents, alkali metals. Moisture sensitive. Reacts violently with water, liberating toxic gas. |
Brand Name: | Zhishang Chemical |
Provide: | Oxalyl Chloride MSDS; Oxalyl Chloride COA |
What is Oxalyl Chloride?
Oxalyl chloride is a synthetic intermediate for medicines, pesticides, coatings, etc. It is used as a raw material for synthesizing antibiotics in medicine, as a raw material for methacrylic phthalocyanate in coatings, and for the synthesis of ultra-efficient sulfonylureas in the pesticide industry. Herbicide benzsulfuron, plant growth regulators, etc., are widely used.
Oxalyl chloride is a relatively active acylating agent and amidating agent, which can be used for the acylation of acids or amines to prepare a variety of pesticides, fungicides, pharmaceutical antitumor agents, X-ray contrast agents, etc. It can also be used as chlorinating agent, carbonylation activator, crosslinking agent for chlorocarbonylation agent, it can also carry out cyclic polycondensation reaction, esterification reaction, etc. It is used in industries such as plastics, polyesters and polyurethanes. Oxalyl chloride is used as an etchant for semiconductor materials in industry. In conclusion, oxalyl chloride is an important raw material for multi-purpose fine chemical products.
Oxalyl Chloride Uses
- Normally used as a poison gas for armed forces usage, and additionally as a chlorinating representative in organic synthesis Analytical reagents.
- Oxalyl chloride is used to prepare cardiolipin analogues that induce peroxidase activity by cytochrome C. It is also used to prepare fluorescent indicator of cytosolic calcium.
- It is an important carboxylic acid derivative, which has important applications in organic synthesis, drug synthesis, etc. It can mainly undergo hydrolysis, alcoholysis, ammonia (amine) hydrolysis, reaction with organometallic reagents, reduction Hydrohalogenation and other reactions.
- Oxalyl chloride is an intermediate or reagent for organic synthesis of pesticides, medicines and coatings. It can be used in pesticides to synthesize sulfonylureas, herbicides benzsulfuron, plant growth regulators, etc.; in medicines, it can be used to synthesize cephalosporins Pu or cefuroxime axetil; in coatings, it can be used to prepare methacryloyl isocyanate, etc.; it is often used to prepare other acid chlorides in laboratories or factories, and it has a wide range of uses.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
- WhatsApp: +86 176 5311 3209
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If you want to buy oxalyl chloride, pls contact us to get a free quote.
Reaction Mechanism of Oxalyl Chloride
Oxalyl chloride is the most active acylating reagent, a resonance hybrid of the limiting structure.
This resonance effect stabilizes the entire molecule and also strengthens the bond between the carbonyl carbon atom and the leaving group. The resonance effect is a stabilizing effect that relies on the overlapping of the bonding atomic orbitals, and acid chlorides may be least affected by this resonance, fatty acids (including unsaturated fatty acids), aromatic acids, organic sulfonic acids and substituted acids (such as amino acids) and halogenated acids, etc.) can generate acid chloride with thionyl chloride in the presence of a catalyst, and the catalyst usually uses N,N-dimethylformamide (DMF), N,N-dimethylaniline and pyridine.
Resolve Resolution of Oxalyl Chloride
The German patent introduces that oxalic acid and phosphorus pentachloride react in phosphorus oxychloride in the presence of triethylamine to obtain oxalyl chloride, and the yield can reach 73%.
Domestic production example: in a 2L four-necked flask with a stirrer, a solid raw material supply funnel and a distillation device, 1kg of phosphorus pentachloride and 12g of triethylamine are suspended in 500g of phosphorus oxychloride, and at a reaction temperature of 60° C. and Under the pressure of 2.5kPa, 100g of water-free oxalic acid was supplied for 40min, and finally stirred at 70°C and 2.5kpa for 30min. During the supply and stirring, in the distillation apparatus, we obtained: w=20.7% oxalyl chloride and w=78.4% trichloride Phosphorus oxide mixture 4979, unreacted phosphorus pentachloride 589 and added triethylamine and residual phosphorus oxychloride in the reactor. In terms of oxalic acid, the yield is 73%; in phosphorus pentachloride, the yield is 80%.
The Japanese patent describes the chlorination of oxalate esters (dimethyl, diethyl, dipropyl or diphenyl) to form chlorine oxalate in the presence of light. For example: 12g of dimethyl oxalate is injected with chlorine gas at 160°C at a rate of 50cm3/min under the illumination of light, and the reaction is carried out for 8h to obtain 10.2g of oxalyl chloride. 17.5g of dipropyl oxalate can be reacted with light at 165℃ for 8h to obtain 8.9g of oxalyl chloride.
The European patent has introduced that oxalyl chloride is obtained through three-step chlorination reaction: 1. trichloroacetyl chloride and ethylene glycol react without solvent to obtain ethylene glycol bis-trichloroacetyl ester; 2. above-mentioned substances are subjected to photochlorination to obtain four Chlorinated ethylene glycol bis-trichloroacetate; ③ This substance is rearranged at 50-160 ° C to obtain oxalyl chloride.
The US patent describes the decomposition of tetrachloroethylene carbonate in the presence of 1% dimethylformamide at 80-85 °C to obtain 79% oxalyl chloride and 21% phosgene.
The Japanese patent describes that tetrachloroglycolide or its polymer is decomposed in the presence of Lewis base to obtain oxalyl chloride. For example: a mixture of 2.99g of tetrachloroglycolide and 0.1g of triethylamine is heated to 64.5-74°C in a chlorinated benzene solvent, kept for 0.5h, and then distilled to obtain oxalyl chloride. Its yield was 89.3% (purity 96.3%).
References
- Oxalyl chloride – WikiPedia
- Dondoni, A.; Perrone, D. (2004). “Synthesis of 1,1-Dimethyl Ethyl-(S)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate by Oxidation of the Alcohol”. Organic Syntheses.; Collective Volume, vol. 10, p. 320
Oxalyl Chloride Supplier and Manufacturer
As a oxalyl chloride supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best oxalyl chloride raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have demand for oxalyl chloride and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide best price and high quality product.
* Sample testing support.
* Every batch of products will be tested to ensureits quality.
*The packing also can be according the customers` requirment.
*Any inquiries will be replied within 24 hours.
*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
After-Sales Service
*The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
*Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Is there a discount?
Different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
1. ≤50kg, Express delivery recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
Quality Control

