N-Acetyl-L-aspartic acid CAS 997-55-7 L-N-AcAsp
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Factory Supply N-Acetyl-L-aspartic acid CAS 997-55-7 L-N-AcAsp with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: N-Acetyl-L-aspartic acid Supplier & Manufacturer
N-Acetyl-L-aspartic acid: The Complete Guide
- Item 1: Basic Info
- Item 2: What is N-Acetyl-L-aspartic acid?
- Item 3: N-Acetyl-L-aspartic acid Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of N-Acetyl-L-aspartic acid
- Item 6: Others
- Item 7: Quality Control of N-Acetyl-L-aspartic acid
- Item 8: Hot Sale Products
- Item 9: Get N-Acetyl-L-aspartic acid Quotation
N-Acetyl-L-aspartic acid for Sale
Basic Info
Basic Info
| Chemical Name: | N-Acetyl-L-aspartic acid |
| Other Name: | L-N-AcAsp; L-n-acetylasparticacid; N-Acetylaspartic acid |
| CAS: | 997-55-7 |
| EINECS: | 213-643-9 |
| Type: | Organic raw materials |
| Molecular Formula: | C6H9NO5 |
| Molecular Weight: | 175.14 |
Chemical Properties
Melting point | 137-140 °C(lit.) |
alpha | 52 º (c=1, HAc) |
Boiling point | 425.3±35.0 °C(Predicted) |
density | 1.422±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Aqueous Acid (Slightly, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly, |
form | Solid |
pka | 3.14±0.10(Predicted) |
color | White to Off-Whiite |
optical activity | [α]20/D +12±1°, c = 2% in 6 M HCl |
Other Info
| Brand Name: | Zhishang Chemical |
| Provide: | N-Acetyl-L-aspartic acid MSDS; N-Acetyl-L-aspartic acid COA |
What is N-Acetyl-L-aspartic acid?
N-acetylaspartic acid or N-acetylaspartic acid (NAA) is a by-product of aspartic acid, with molecular formula of C6H9NO5 as well as molecular weight of 175.139.
NAA is the 2nd highest possible focus particle in the brain, second just to amino acid glutamate. It was discovered in adult minds of nerve cells, oligodendrocytes as well as myelin, and was manufactured by the amino acid aspartic acid and acetyl coenzyme A in mitochondria.
N-acetyl-L-aspartic acid, abbreviated as L-N-AcAsp, is an amino acid derivative, in which the acyl group is designated as the acetyl group. Acetylation of L-aspartic acid is achieved by first neutralizing with potassium carbonate to pH 7.0, and then adding acetic anhydride. After the hydrochloric acid acidification product is used, the acetylation product obtained is purified by HPLC.
N-Acetyl-L-aspartic acid Uses
NAA may act as a neurotransmitter in the brain by acting on metabolic glutamate receptors.
NAA may be a sign of creativity. The high level of NAA in the hippocampus is related to the better performance of human working memory.
N-acetyl-L-aspartate is used in the biological research of metabolic changes related to schizophrenia.
N-acetyl-L-aspartic acid can be synthesized as a reactant:
- Protection of homoserine by selective reduction and acid-catalyzed cyclization γ- Lactone.
- The racemic amino-substituted succinimide derivatives were obtained by ring condensation reaction.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
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Application of N-Acetyl-L-aspartic acid
Various functions provided by NAA are under investigation, but the main proposed functions include:
- Neuron penetrant involved in brain fluid balance.
- The acetate source of lipid and myelin synthesis in oligodendrocytes, which are neuroglial cells myelinated by neuronal axons.
- Precursor of synthetic neuropeptide N-acetylaspartate glutamate.
- Contribute to the energy production of amino acid glutamate in neuron mitochondria.
In the brain, NAA is believed to exist mainly in the neuronal cell body, where it acts as a neuronal marker, but it can also spread freely to the entire nerve fiber.
Others
CN201710830763.2 reports a method and its application of using diagnostic markers to evaluate the early toxicity of trace exogenous chemicals.
A method for evaluating the early toxicity of trace exogenous chemicals using diagnostic markers. The diagnostic markers include: L-valine, N-acetyl-L-aspartic acid, lysolecithin, creatinine, and 2-phosphoglycerol Any one or more of acids. In the process of studying exogenous chemicals, it was found that exogenous chemicals can disrupt the amino acid balance in zebrafish and affect the catabolism of proteins. This disturbance in the developmental stage is associated with its toxicity mechanism. The inventors found that the zebrafish The combination of modeling and metabolomics techniques can greatly improve the sensitivity of toxicity prediction methods.
Therefore, the changes of the above-mentioned zebrafish metabolite indicators can be used to judge the early toxicity of exogenous chemicals.
Reference
- N-Acetylaspartic acid – WikiPedia
- CN201710830763.2 A method for evaluating the early toxicity of trace exogenous chemicals using diagnostic markers and its application
N-Acetyl-L-aspartic acid Suppliers and Manufacturers
As a n-acetyl-l-aspartic acid supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best n-acetyl-l-aspartic acid raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for n-acetyl-l-aspartic acid and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of N-Acetyl-L-aspartic acid
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