Mycophenolate Mofetil CAS 128794-94-5
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Factory Supply Mycophenolate Mofetil CAS 128794-94-5 with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Mycophenolate Mofetil Supplier & Manufacturer
Mycophenolate Mofetil: The Complete Guide
- Item 1: Basic Info of Mycophenolate Mofetil
- Item 2: What is Mycophenolate Mofetil?
- Item 3: Mycophenolate Mofetil Uses
- Item 4: The Manager has Something to Say
- Item 5: Potentially dangerous interactions with other drugs
- Item 6: Reference
- Item 7: Quality Control of Mycophenolate Mofetil
- Item 8: Hot Sale Products
- Item 9: Get Mycophenolate Mofetil Quotation
Mycophenolate Mofetil for Sale
Basic Info of Mycophenolate Mofetil
Basic Info
Chemical Properties
Other Info
Basic Info
Chemical Name: | Mycophenolate Mofetil |
Other Name: | 6-(1,3-Dihydro-4-hydroxy-6-Methoxy-7-Methyl-3-oxo-5-isobenzofuranyl)-4-Methyl-4-hexenoicacid2-(4-Morpholinyl)ethylester |
CAS: | 128794-94-5 |
EINECS: | / |
Type: | Pharmaceutical raw materials; Pharmaceutical intermediates |
Molecular Formula: | C23H31NO7 |
Molecular Weight: | 433.49 |
Chemical Properties
Melting point | 95-96°C |
Boiling point | 637.6±55.0 °C(Predicted) |
density | 1.222±0.06 g/cm3(Predicted) |
storage temp. | room temp |
solubility | DMSO: ≥15mg/mL |
form | powder |
pka | 5.6(at 25℃) |
color | white to beige |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
Other Info
Brand Name: | Zhishang Chemical |
Provide: | Mycophenolate Mofetil MSDS; Mycophenolate Mofetil COA |
What is Mycophenolate Mofetil?
Morpholine ethyl mycophenolate is the precursor of active mycophenolic acid (MPA), an immunosuppressive component extracted from penicillium culture medium, and an inhibitor of hypoxanthine mononucleotide dehydrogenase (IMPDH), which is necessary for the synthesis of purine nucleotides, especially for the classical synthesis of guanine nucleotides required by lymphocytes.
Mycophenolate mofetil was launched in the United States in 1995, which is its first market in the world. It is made use of to stop severe renal transplant rejection, integrate with other immunosuppressive therapies, and treat refractory acute renal transplant denial. Mycophenolate mofetil has actually improved oral absorption and also bioavailability. It is the forerunner of mycophenolic acid (MPA), which is the fermentation product of several penicillium types.
MPA is a careful, relatively easy to fix, non competitive prevention of inosine dehydrogenase and guanylate synthetase. It hinders the de now pathway of purine biosynthesis. It was discovered that MPA had much more efficient antiproliferative impact on T and B lymphocytes than various other cell types. It is reported that compared to other immunosuppressants, mycophenolate mofetil has advantages as a result of its distinct system of activity and also outstanding safety and security in long-term use.
Mycophenolate Mofetil Uses
- Mycophenolate mofetil has been made use of to deal with wild-type embryos to hinder nucleotide synthesis.
- Mycophenolate mofetil is an immunosuppressant used in body organ hair transplant as well as can likewise be made use of to treat autoimmune myasthenia gravis (MG).
- MMF is made use of to stop organ denial in clients receiving kidney, liver and also heart transplant; It is usually utilized in mix with various other immunosuppressants for this sign. In dermatology, MMF is especially appropriate for the treatment of autoimmune vesicular diseases (bullous pemphigoid and pemphigus) as a monotherapy or as a steroid economizer. It can also be used to deal with inflammatory skin diseases moderated by neutrophil infiltration, such as pyoderma gangrenosum as well as psoriasis.
- Mycophenolate mofetil is a prodrug that is cleaved in vivo by nonspecific esterases to produce the moms and dad substance, mycophenolic acid. Mycophenolic acid blocks inosine monophosphate dehydrogenase as well as is a potent immunosuppressant. Mycophenolate mofetil is made use of to prevent organ denial in clients receiving allograft kidney, heart or liver hair transplant. Mycophenolate mofetil needs to be used along with cyclosporine and corticosteroids.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
- WhatsApp: +86 176 5311 3209
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- Skype: +86 176 5311 3209
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If you want to buy mycophenolate mofetil, pls contact us to get a free quote.
Potentially dangerous interactions with other drugs
- Antipsychotics: Avoid use with clozapine (increased risk of agranulocytosis).
- Antiviral drugs: Mycophenolate mofetil and acyclovir or orciclovir are given in higher concentrations when both are used together.
- Antacids: The absorption of mycophenolate mofetil is decreased in the presence of magnesium and aluminum salts.
- Antimicrobials: Metronidazole and norfloxacin may reduce the bioavailability of mycophenolate mofetil; rifampicin reduces the concentration of active metabolites.
- Cholestyramine: The oral bioavailability of mycophenolate mofetil is reduced by 40%.
- Cyclosporine: Some studies have shown that cyclosporine reduces plasma MPA AUC levels; other studies show an increase – no dose change required.
- Iron preparations: Can significantly reduce the absorption of mycophenolate mofetil.
- Sevelamer: Reduces mycophenolate mofetil levels.
- Tacrolimus: Increase MPA concentration – no dose change required, but close monitoring.
Reference
Mycophenolate mofetil – PubChem
Mycophenolate Mofetil Supplier and Manufacturer
As a mycophenolate mofetil supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best mycophenolate mofetil raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have demand for mycophenolate mofetil and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.
Service
FAQ
Shipping
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Mycophenolate Mofetil
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