Methyl Anthranilate CAS 134-20-3

Factory Supply Methyl Anthranilate CAS 134-20-3 with Best Price

  • Appearance: Yellow liquid
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Methyl Anthranilate Supplier & Manufacturer

Basic Info

What is Methyl Anthranilate?

Methyl anthranilate is one of edible spices. It is mostly used as a raw material for flavoring. It is widely found in natural spice plants, especially in jasmine oil, orange leaf oil, and grapes planted in cold regions.

Methyl anthranilate is an important intermediate of dyes, medicines, pesticides, spices and other products, and is widely used in the fields of medicine, pesticides, spices processing, and fine chemicals. In terms of dyes, it is used to manufacture azo dyes, anthraquinone dyes, and indigo dyes; in medicine, it is used to manufacture antiarrhythmic drugs changroline, vitamin L, non-steroidal anti-inflammatory analgesics mefenamic acid, Yantongjing, non-barbiturate hypnotic methaphenone, strong tranquilizer Telden; it can also be used as a chemical reagent, and can be used as a complex reagent for the determination of cadmium, cobalt, mercury, magnesium, nickel, lead, zinc and cerium, etc. , together with 1-naphthylamine can be used to determine nitrite. In nature, methyl anthranilate exists in tahua oil, neroli oil, ylang ylang, jasmine oil, tuberose oil, etc., and has high added value and wide application value.

Since the exploration of methyl anthranilate in neroli oil in 1899, individuals have actually together discovered the presence of anthranilate compounds in lots of all-natural plants such as oranges, lemon jasmine, ylang-ylang, gardenia, and so on. flavor industry. Anthranilate is both an ester and also an aromatic primary amine, so it has the twin features of ester as well as amine. When it is included in flavors including various other aldehydes, it can go through condensation reaction with aldehydesiff to produce base (Sch near Base) with more secure properties and richer fragrance.

Methyl Anthranilate Uses

The synthesis of methyl anthranilate was reported at the end of the 19th century, but it was not used as a food additive until the middle of the 20th century.

Anthranilates are both esters and primary aromatic amines, thus possessing dual properties of esters and amines. With the deepening of its research, new uses are constantly being discovered, such as antimicrobial agents, fruit antifreeze agents, pest control agents, and so on. At the same time, individual local mild allergic physiological effects caused by methyl anthranilate have also attracted people’s attention. However, the International Spice Association believes that it is allowed to mix and match spices as a spice.

Methyl anthranilate is widely used in the fields of dye manufacturing, fragrance manufacturing, pharmaceutical manufacturing, pesticide manufacturing, food processing and fine chemical synthesis.

Due to the needs of social and industrial development, the demand for methyl anthranilate will increase.

In terms of fragrance synthesis, because of its strong floral and fruity aroma, it is widely used in the synthesis of daily flavors and food flavors, and can be used in various fruit flavors such as citrus, strawberry, watermelon, melon, lemon, and dried plum. Medium; used in dyes to produce anthraquinone dyes, indigo dyes and azo dyes – disperse orange, disperse yellow, neutral blue and other dyes; used in pharmaceutical manufacturing to make non-steroidal anti-inflammatory analgesics A Fenamic acid, synthetic vitamin L and antiarrhythmic drug changroline, non-barbiturate hypnotics (such as methaphen) and other medicines; as a chemical reagent, it works together with 1-naphthylamine for the determination of nitrite ; Can be used as a complexing agent for various metal ions, such as Mg, Hg, Pb, Zn, etc.

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Application of Methyl Anthranilate

Bromhexine hydrochloride is a synthetic drug obtained through structural modification of Vasicine, and its hydrochloride is commonly used. It is white to off-white crystalline powder, easily soluble in methanol and ethanol, slightly soluble in water. It is mainly used for the mucus-producing cells of the trachea and bronchial mucosal glands to make them secrete low-viscosity small molecule mucin, and thus restore the rheological properties of trachea and bronchial secretion to normal, reduce sticky sputum, and dilute sputum , easy to spit out.

CN201310540763.0 discloses the synthetic production method of bromhexine hydrochloride, the method takes methyl anthranilate as starting raw material, synthesizes 3,5-dibromomethyl anthranilate through bromine, hydrochloric acid bromination reaction, Then use potassium borohydride and ethanol as raw materials for reduction reaction to synthesize 3,5-dibromo-o-aminophenyl alcohol, then condense with N-methylcyclohexylamine to form bromhexine, add hydrochloric acid to form a salt, and synthesize bromhexine hydrochloride crude product, Finally, recrystallize with ethanol to obtain bromhexine hydrochloride. The synthesis route adopted by the invention is short, the operation is simple and convenient, the starting material is easy to obtain, the performance of the intermediate is stable, the product yield is high, the production cost is low, and it is suitable for industrial scale production.

Preparation of Methyl Anthranilate


  1. Methyl anthranilate – WikiPedia
  2. Jin Xin, Jia Weimin.Study on the New Synthesis Process of Methyl Anthranilate[J].Perfume, Fragrance and Cosmetics, 2007(03):5-6.
  3. [Chinese invention, Chinese invention authorized] CN201810813480.1 One-step production process of methyl anthranilate

Methyl Anthranilate Supplier and Manufacturer

As a methyl anthranilate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best methyl anthranilate raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for methyl anthranilate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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