Magnesium Sulfate CAS 7487-88-9

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  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Magnesium Sulfate Supplier & Manufacturer

Basic Info

What is Magnesium Sulfate?

The chemical formula of magnesium sulfate is MgSO4, and the formula weight is 120. White crystals, it has a variety of crystalline hydrates, among which MgSO4·7H2O is called Epsom salt, and MgSO4·H2O is called magnesium sulfate. The formula weight of magnesium sulfate heptahydrate is 246.46, colorless orthorhombic or monoclinic prism crystals, and the density is 1.68g/cm3. Weathering in dry air, easily soluble in water, slightly soluble in ethanol, melts in crystal water at 68°C, loses 6 crystal water at 150°C, and generates magnesium sulfate, loses all crystal water at 250°C and becomes anhydrous, anhydrous The water density is 2.66g/cm3, the melting point is 1124°C, and it has a bitter and salty taste. It is used as analytical reagent and mordant, also used in tanning, papermaking, ceramic industry, etc., and can also be used as oral laxative. It can be prepared by reacting sulfuric acid with magnesium oxide, magnesium hydroxide or magnesium carbonate.

When magnesium sulfate is used as a volumetric laxative and anticonvulsant, oral administration of sulfate ions and magnesium ions is not easily absorbed by the intestinal wall, which increases the osmotic pressure in the intestines, prevents water absorption in the intestines, increases the volume of the intestines, and the intestines are blocked. Dilation, so as to stimulate the intestinal wall to increase peristalsis and defecation. It is used to treat constipation, eliminate gastrointestinal poisons and catharsis after taking anthelmintics. After intravenous or intramuscular injection, because magnesium ions have a blocking effect on neuromuscular junction conduction, it has anticonvulsant effect, and is used to treat equine diaphragmatic spasm and relieve muscle rigidity symptoms of tetanus. If the dosage is too large or the intravenous injection speed is too fast, the blood pressure will drop suddenly and the respiratory depression will be suppressed. Immediately intravenous injection of 5% calcium chloride or calcium gluconate should be rescued.

Magnesium Sulfate Uses

Magnesium sulfate is a cofactor for many enzymes. It has an important relationship with muscle contraction and nerve conduction. It has anticonvulsant (relieving eclampsia, tetanus), dilating blood vessels, quickly and strongly lowering blood pressure, correcting hypomagnesemia, and is also used for catharsis and choleresis (see digestive system drugs). It is also currently used for arrhythmia and to reduce the toxicity of digitalis in heart failure.

  1. Catharsis effect: take it orally, drink plenty of water when using it.
  2. Choleretic effect: Oral administration of high-concentration (33%) solution can stimulate the duodenal mucosa to relax the sphincter of the common bile duct, contract the gallbladder, and promote bile discharge.Effects on the central nervous system: Injecting this product can inhibit the central nervous system, block peripheral neuromuscular junctions to produce sedative, antispasmodic, and skeletal muscle relaxation effects, and can also reduce intracranial pressure.
  3. Effects on the central nervous system: Injecting this product can inhibit the central nervous system, block peripheral neuromuscular junctions to produce sedative, antispasmodic, and skeletal muscle relaxation effects, and can also reduce intracranial pressure.
  4. The effect on the cardiovascular system: when given by injection, excessive magnesium ions can directly relax the smooth muscle of peripheral blood vessels, dilate blood vessels and lower blood pressure.
  5. Anti-inflammation and anti-swelling effect: Applying 50% solution of this product to hot compress the affected area can reduce inflammation and swelling.

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Application of Magnesium Sulfate

The Usage of Magnesium Sulfate

  • Oral catharsis
    50% magnesium sulfate solution is not absorbed when taken orally, and a certain osmotic pressure is formed in the intestine to keep a large amount of water in the intestine, which stimulates intestinal peristalsis and defecation. Clinically, it is often used for intestinal examination or preoperative preparation, removal of intestinal toxins, and also for catharsis of some anthelmintics.
    Usage: 10 ml of 50% magnesium sulfate solution, take it on an empty stomach in the morning, and drink 100-400 ml of water at the same time.
  • Oral choleretic
    Oral administration of high-concentration (33%) magnesium sulfate solution, or direct infusion into the duodenum with a catheter can stimulate the duodenal mucosa, reflexively cause the relaxation of the common bile duct sphincter, contraction of the gallbladder, promote gallbladder emptying, and produce choleretic effect. Clinically used for obstructive jaundice and chronic cholecystitis.
    Usage: (33%) magnesium sulfate solution, 10 ml each time, three times a day, before meals or between meals.
  • Injection to suppress central excitation
    Increasing the concentration of magnesium ions in the extracellular fluid can inhibit the central nervous system, reduce the release of acetylcholine from the motor nerve endings, and block the peripheral neuromuscular junction, thereby producing sedative, antispasmodic, and relaxing skeletal muscles. Internal pressure, clinically used for anticonvulsions, eclampsia, uremia, tetanus, hypertensive encephalopathy and acute renal hypertensive crisis.
    Usage: Intramuscular injection of 25% magnesium sulfate injection, 4-10 ml each time; or dilute 10 ml of 25% magnesium sulfate injection with 5%-10% glucose injection to 1% or 5% concentration and then instill intravenously.
  • Injection to dilate blood vessels
    Excessive injection of magnesium ions can directly relieve peripheral vascular smooth muscle, cause impulse transmission disorder of sympathetic ganglion, thereby dilate blood vessels, lower blood pressure, and treat angina pectoris.
    Usage: Dilute 10ml of 10% solution with 10ml of 5%~10% glucose injection and inject slowly intravenously, once a day.
  • External application anti-inflammatory and detumescence
    50% magnesium sulphate solution is applied externally to hot compress the affected part, which can reduce inflammation and detumescence, and is used to treat phlebitis.
    The action principle of magnesium sulfate wet compress with medicinal liquid extravasation: 50% magnesium sulfate solution is a hypertonic solution for interstitial fluid, and local wet compress can generate high osmotic pressure. It can be sucked out within a short period of time to reduce swelling, thereby reducing the damage of edema to local tissues and playing a local therapeutic role.
    The principle of magnesium sulfate hot compress can reduce swelling: because magnesium sulfate can antagonize calcium ions, and calcium ions are involved in smooth muscle contraction, so magnesium sulfate can relax skin and subcutaneous tissue vascular smooth muscle (note that it is not vascular endothelial cells), reduce capillary blood pressure, Reduce local exudation and edema. The smooth muscle content of large blood vessels is small, so it is mainly used for superficial inflammation.

Magnesium Sulfate Suppliers and Manufacturers

As a magnesium sulfate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best magnesium sulfate raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for magnesium sulfate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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