Lowest price 100% Pure Clobetasol powder CAS 25122-46-7 Clobetasol propionate

Basic Info

Model No.: LYN- 25122-46-7

Shelf Life: 2 Years

Form:: Powder

CoA: Available

Sample: Free

CAS: 25122-46-7

Name:: Clobetasol Propionate

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

Port: Shanghai,Tianjin,Qingdao

Product Description

Lowest price 100% Pure Clobetasol powder CAS 25122-46-7 Clobetasol propionate 

Product Introduction

Name: Clobetasol propionate

C.A.S NO. : 25122-46-7

Synonyms: 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate

EINECS NO.: 246-634-3

Molecular formula: C25H32ClFO5

Molecular weight : 466.97

Assay: 99%

Characteristic: White crystalline powder

Melting point: 196℃

Clobetasol propionate is a corticosteroid used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak.

Main Functions & Applications of Clobetasol propionate:

Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than prednisone, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary – adrenal strong inhibition:

1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. 

2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins. 

 

Specification: 

Test items

Standard

Result

Description

White to off- White powder

Conforms

 

Identification

IR

IR spectrum of sample is the same as working standard

Conforms

HPLC

HPLC RT of the sample is the same as the working standard

Conforms

Melting point

165.0°C~169.0°C

165.8°C~167.0°C

Optical rotation

-23°~-29°

-27.4°

Loss on drying

NMT 1.0 %

0.17%

Residue on ignition

NMT 0.1 %

0.03%

Heavy metals

NMT 20ppm

Conforms

Related substances

Impurity A

NMT 0.1 %

Not detected

Impurity B

NMT 0.1 %

Not detected

Impurity C

NMT 0.1 %

0.02%

Single impurity

NMT 0.2 %

0.17%

Total impurity

NMT 1.0 %

0.60%

Assay

NLT 99.0%

99.0%

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