Levetiracetam CAS NO 102767-28-2

Basic Info

Model No.: X-CAS 102767-28-2

CAS:: 102767-28-2

EINECS:: 200-659-6

MF:: C8H14N2O2

MW:: 170.21

Density:: 1.168 G/cm3

MP:: 118-119°C

Bp:: 395.9ºC At 760 MmHg

FP:: 193.2ºC

Additional Info

Packaging: 25kg/drum

Productivity: 100000kg per month

Brand: ZHISHANG

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE API

HS Code: 2933990090

Port: Shanghai,Tianjin,Qingdao

Product Description

Levetiracetam CAS NO 102767-28-2

92.25 g (0.5 mol) of (S) -2-amino-4-methylthiobutanamide was dissolved in 600 ml of methylene chloride and 84 g of anhydrous sodium sulfate was added at room temperature. Then cooled to 0 ° C and a solution of 115 g of KOH and 8.1 g (0.025 mol) of tetrabutylammonium bromide in 100 ml of dichloromethane was added. At the same temperature, a solution of 77.5 g (0.55 mol) of 4-chlorobutyryl chloride in 100 ml of methylene chloride was added dropwise. During the dropwise addition, 550 ml of methylene chloride was continuously added to dilute the reaction liquid. After the addition was complete, stir at 0 ° C for 2h and then add 29g KOH. After 4.5 h of reaction, 29 g KOH was added. The filtrate was concentrated under reduced pressure and the residue was purified by chromatography on silica gel (methylene chloride-methanol-ammonia, 95.5: 4.5: 0.2 μ / μ / μ) to give 66 g of (S) -α- [2 – (methylthio) ethyl] -2-oxo-1-pyrrolidineacetamide as a white powder in 61% yield.


50 g of Raney Ni, 386 ml of water and 7 g of (S) -α- [2- (methylthio) ethyl] -2-oxo-1-pyrrolidineacetamide were added to the reaction flask at 75 ° C Stir 1h. Filter, steam distilled off under reduced pressure. 5.3g of the residue was recrystallized from 60ml of ethyl acetate to give 3.87g of levetiracetam melting at 112 ~ 115 ° C, a yield of 69%.

Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the raw material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories. The former is a class of cosmetics in the main raw materials, cosmetics in the possession of a large proportion of the cosmetics play a major role in the role of the material. The latter is the formation of cosmetics, stability or to give color, smell and other characteristics of the role of these substances in the cosmetic formula is not used, but it is extremely important. Cosmetics are natural, synthetic or extracted from the role of different substances as raw materials, by heating, mixing and emulsification and other production processes processed from the chemical mixture.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.It is one substance or mixture during the medicine making period uut it can not be taken directly by patients.

3> Fragrance And Spices: Spice is a substance that can be scented by smelling or scented by taste, and is the raw material for the preparation of the fragrance. Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, pesticides, pharmaceuticals, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion, usually in resin, or oil, or emulsion is given priority to, add or not add pigment, filler, add the corresponding additives, organic solvents or water preparation of viscous liquid.


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1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

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3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
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5.Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.


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