Isopropyl Nitrite CAS 541-42-4

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  • Appearance: Colorless liquid
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Isopropyl Nitrite Supplier & Manufacturer

Basic Info of Isopropyl Nitrite

What is Isopropyl Nitrite?

Isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a transparent light yellow oil, insoluble in water.

Isopropyl nitrite is associated with maculopathy, visual impairment of central scotoma, bilateral foveal macula, and interruption of internal / external segment (is/os), which may be reversible.

Isopropyl Nitrite Uses

  • Isopropyl nitrite was used to prepare heterocyclic amide as rip1 kinase inhibitor. Jet propellant.
  • Isopropyl nitrite is one of the compounds used as poppers, an inhaled drug that can cause brief pleasure. Isopropyl nitrite has largely replaced isobutyl nitrite in popcorn.

Production Method of Isopropyl Nitrite

In a reaction flask equipped with a stirrer, a thermometer and a dropping funnel, add 227.7g (3.3mol) sodium nitrite and 1L water, stir to dissolve, cool to -5°C in an ice-salt bath, and slowly add dropwise to 0. A solution of 147 g of concentrated sulfuric acid, 60 mL of water, and 180 g (3.0 mol) of isopropanol (2) at a temperature of ℃. The dropping rate was controlled at the temperature of the reaction solution at -2 to 0°C, and the addition was completed in about 2 hours. Low temperature reaction 1.5h.

The organic layer was separated, washed with saturated brine containing a small amount of sodium bicarbonate, dried over anhydrous magnesium sulfate, distilled under reduced pressure, and the fractions at 39-40°C/99.08kPa were collected to obtain 190 g of isopropyl nitrite (1), which was collected rate of 71%.


  1. Isopropyl nitrite – WikiPedia
  2. Isopropyl nitrite – PubChem

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Isopropyl Nitrite Supplier and Manufacturer

As a isopropyl nitrite supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best isopropyl nitrite raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for isopropyl nitrite and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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