
Isopropyl Nitrite CAS 541-42-4
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- Appearance: Colorless liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Isopropyl Nitrite Supplement



Isopropyl Nitrite: The Complete Guide
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Isopropyl Nitrite for Sale
Basic Info of Isopropyl Nitrite
Chemical Name: | Isopropyl Nitrite |
Other Name: | Isopropyl nitrate; 1-methylethylnitrite; 2-propanolnitrite; 2-propyl nitrite |
CAS: | 541-42-4 |
EINECS: | 208-779-0 |
Type: | Organic raw materials |
Molecular Formula: | C3H7NO2 |
Molecular Weight: | 89.09 |
Boiling point | 39℃ |
density | 1.02 |
refractive index | nD20 1.3520 |
Fp | -37℃ |
EPA Substance Registry System | Nitrous acid, 1-methylethyl ester (541-42-4) |
Brand Name: | Zhishang Chemical |
Provide: | Isopropyl Nitrite MSDS; Isopropyl Nitrite COA |
What is Isopropyl Nitrite?
Isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a transparent light yellow oil, insoluble in water.
Isopropyl nitrite is associated with maculopathy, visual impairment of central scotoma, bilateral foveal macula, and interruption of internal / external segment (is/os), which may be reversible.
Isopropyl Nitrite Uses
Isopropyl nitrite was used to prepare heterocyclic amide as rip1 kinase inhibitor. Jet propellant.
Production Method of Isopropyl Nitrite
In a reaction flask equipped with a stirrer, a thermometer and a dropping funnel, add 227.7g (3.3mol) sodium nitrite and 1L water, stir to dissolve, cool to -5°C in an ice-salt bath, and slowly add dropwise to 0. A solution of 147 g of concentrated sulfuric acid, 60 mL of water, and 180 g (3.0 mol) of isopropanol (2) at a temperature of ℃. The dropping rate was controlled at the temperature of the reaction solution at -2 to 0°C, and the addition was completed in about 2 hours. Low temperature reaction 1.5h.
The organic layer was separated, washed with saturated brine containing a small amount of sodium bicarbonate, dried over anhydrous magnesium sulfate, distilled under reduced pressure, and the fractions at 39-40°C/99.08kPa were collected to obtain 190 g of isopropyl nitrite (1), which was collected rate of 71%.
Reference
- Isopropyl nitrite – WikiPedia
- Isopropyl nitrite – PubChem
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Quality Control of Isopropyl Nitrite

