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2-Dimethylaminoisopropyl Chloride Hydrochloride CAS 4584-49-0

2-Dimethylaminoisopropyl Chloride Hydrochloride CAS 4584-49-0 with Best Price

  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 2-Dimethylaminoisopropyl Chloride Hydrochloride Supplement

Basic Info of 2-Dimethylaminoisopropyl Chloride Hydrochloride

What is 2-Dimethylaminoisopropyl Chloride Hydrochloride?

2-Dimethylaminoisopropyl chloride hydrochloride is obtained by chlorination of 1-dimethylamino-2-propanol with thionyl chloride.

2-Dimethylaminoisopropyl chloride hydrochloride is hygroscopic. Soluble in water.

2-Dimethylaminoisopropyl chloride hydrochloride is incompatible with solid oxidants. Amines are chemical bases. They counteract acids to form salt and also water. These acid-base reactions are exothermic. The warm launched per mole of amine in neutralization is largely independent of the toughness of amine as a base. Amines might be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides as well as acyl halides. Flammable gaseous hydrogen is generated by the combination of amine as well as strong lowering representative (such as hydride).

Flash point data of 2-dimethylaminoisopropyl chloride hydrochloride is not available; Nonetheless, 2-dimethylaminoisopropyl chloride hydrochloride may be flammable.

2-Dimethylaminoisopropyl Chloride Hydrochloride Uses

  1. 2-chloro-n, n-dimethylpropylamine hydrochloride (dmic) is utilized as an intermediate in medication synthesis (such as isothiophene, methadone and promethazine).
  2. Hydrochloride of 2-dimethylaminoisopropyl chloride for the synthesis of lipophilic chalcone analogues as antituberculous agents.
  3. 2-Dimethylaminoisopropyl chloride hydrochloride is used in the pharmaceutical industry as an intermediate of the central inhibitory drug Meisantong and the antihistamine drug phenergan.

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Chemical Reaction of 2-Dimethylaminoisopropyl Chloride Hydrochloride

Follow Schultz and Sprague’s procedure, J. am. Chemistry. Soc., 70, 48 (1948), containing 3.77 g of solution.
1-dimethylamino-2-propanol and 10 ml. Cool 100 ml of chloroform to a temperature of about 0 ° C with stirring. The solution is 5.72g.
2 ml of freshly distilled thionyl chloride. Add chloroform to it. The reaction mixture was brought to ambient temperature within about 30 minutes and then heated to reflux temperature for 30 minutes.
The precipitated material re dissolves when heated. 1-dimethylamino-2-chloropropane hydrochloride begins to crystallize from boiling solvent.
The reaction mixture was cooled, diluted with ether and filtered.
The reaction product containing 1-dimethylamino-2-chloropropane hydrochloride weighs about 5.5G. (95% yield).

Quality Control of 2-Dimethylaminoisopropyl Chloride Hydrochloride

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