SHANDONG ZHISHANG CHEMICAL CO.LTD.

High Purity Methylprednisolone powder CAS 83-43-2

Basic Info

Model No.: LYN- 83-43-2

Shelf Life: 2 Years

Form:: Powder

CoA: Available

Sample: Free

CAS: 83-43-2

Name:: Methylprednisolone

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

Port: Shanghai,Tianjin,Qingdao

Product Description

High Purity Methylprednisolone powder CAS 83-43-2 

 Introduction:

 

English name: Methylprednisolone

 

Molecular Formula:C22H30O5
Molecular Weight:374.4706
CAS Registry Number:83-43-2
EINECS:201-476-4
Quality:BP/CP

 

Density:1.28g/cm3
Melting point:228-237°C (dec.)
Boiling point:571.8°C at 760 mmHg
Refractive index:1.602
Flash point:313.7°C
Vapour Pressur:1.86E-15mmHg at 25°C 

 

Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug. It is marketed in the USA and Canada under the brand names Medrol and SoluMedrol.It is also available as a generic drug.It is a variant of prednisolone, methylated at carbon 6 of the B ring.

 

 Specification

 

Items Specifications Results
Appearance White to practically white crystalline powder White crystalline powder
Melting 240°C 239°C
Identification A:IR Complies
B:UV Complies
C: Positive reaction Complies
Solubility Practically insoluble in water sparingly soluble in alcohol, in dioxane, and in methanol; slightly soluble in acetone and in chloroform; very slightly soluble in ether Complies
Specific rotation +79o~+86o +82.7o
Loss on drying ≤1.0% 0.10%
Residue on ignition ≤0.2% 0.03%
Chromatographic purity A: Individual impurity ≤1.0% 0.40%
B: Total impurities≤2.0% 1.10%
Assay 97.0~103.0% 99.80%
Conclusion The results conforms to the USP34

 

  Function:

 

1Like most adrenocortical steroids, methylprednisolone is typically used for its anti-inflammatory effects;

 

2Methylprednisolone is also prescribed for nonpenetrating spinal cord injuries;

 

 

 

3Common uses include arthritis therapy and short-term treatment of bronchial inflammation or acute bronchitis due to various respiratory diseases;

 

 

 

4Methylprednisolone can also used for vestibular neuritis;

 

 

 

5Methylprednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.

 

Application:

 

1-Applied in pharmaceutical field, It is used both in the treatment of acute periods and long-term management of autoimmune diseases, most notably systemic lupus erythematosus;

 

2It is also used as a treatment for multiple sclerosis.

 

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