Guaiazulene CAS 189-84-9
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Factory Supply Guaiazulene CAS 189-84-9 with Best Price
- Appearance: Blue powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Guaiazulene Supplier & Manufacturer
Guaiazulene: The Complete Guide
Guaiazulene for Sale
Basic Info of Guaiazulene
Basic Info
Chemical Properties
Other Info
Basic Info
Chemical Name: | Guaiazulene |
Other Name: | 1,4-Dimethyl-7-(1-methylethyl)azulene; Guaiazulen |
CAS: | 489-84-9 |
EINECS: | 207-701-2 |
Type: | Plant Extract; Flavor and Fragrance; Pharmaceutical raw materials |
Molecular Formula: | C15H18 |
Molecular Weight: | 198.3 |
Chemical Properties
Melting point | 27-29 °C (lit.) |
Boiling point | 153 °C/7 mmHg (lit.) |
density | 0.976 g/mL at 25 °C (lit.) |
refractive index | 1.3166 (estimate) |
Fp | >230 °F |
storage temp. | Sealed in dry,2-8°C |
solubility | Chloroform (Slightly), Methanol (Sparingly) |
form | Low Melting Crystalline Solid |
color | Dark blue |
Water Solubility | Soluble in alcohol, water, 0.1115 mg/L @ 25°C (est). |
Other Info
Brand Name: | Zhishang Chemical |
Provide: | Guaiazulene MSDS; Guaiazulene COA |
What is Guaiazulene?
Guaiazulene, also referred to as azulon or 1,4-dimethyl-7-isopropylazulene, is a dark blue crystalline hydrocarbon. A derivative of azulene, guaiazulene is a bicyclic sesquiterpene, which is the element of some crucial oils, mainly guaiac oil as well as chamomile oil, which are likewise commercial resources. Different soft reefs additionally contain guaiacol as the primary pigment. Contrary to the crystalline nature of the moms and dad azulene, its reduced melting point makes guaiacene tough to treat. The electronic frameworks (as well as shades) of guaiacene and azulene are very comparable.
Guaiacol blue oil hydrocarbon is a blue oily liquid or light blue purple flake crystal, which is sensitive to light. It changes from blue to green after seeing light, and finally turns yellow. It is stable to heat, weak acid and weak alkali. It is soluble in liquid paraffin, soluble in hot ethanol and ether, and extremely difficult to dissolve in water. Guaiacol has anti-inflammatory effect, has significant inhibitory effect on dextran induced edema in rats, only moderate inhibition on hyaluronidase, formaldehyde and histamine induced edema, can inhibit the release of histamine and 5-hydroxytryptamine, and has anti histamine and anti hyaluronic acid effects, can reduce the permeability of capillaries, can enhance the regeneration process, weaken the allergic reaction, has local anesthetic effect, and can be used in bronchial asthma Rheumatic fever, allergic gastroenteritis, eczema, etc. it has anti allergic and anti-inflammatory effects. It is also used for radiation heat burns, cracking, frostbite and promoting wound healing.
Guaiazulene Uses
- Guaizulene is a cosmetic pigment additive authorized by FDA. It – or its 3-sulfonate – is a component in some skin treatment items, as well as various other skin comforting substances such as allantoin.
- Guaiaazulene (azulon, vetivazulen) is a bicyclic sesquiterpene, which belongs of some essential oils.
- Guaizulene has applications as an unstable color with well-known dissipation prices to indicate completion of use of numerous items, such as insecticide strips.
- Guaiacol has anti-inflammatory as well as advertising tissue granulation regeneration, can advertise the healing of burned and scalded wounds, as well as has anti warmth, anti radiation as well as anti chapping effects. It is utilized to deal with burns, heats, chaps, chilblains, eczema, dermatitis and avoid high warmth radiation.
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This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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Application of Guaiazulene
Guaiazulene can be used as a starting product for the synthesis of:
- Azulene based dye molecules, such as 3- (7-isopropyl-1,4-dimethylazulen-3-yl) – 2-cyanoacrylic acid as well as 5- (7-isopropyl-1,4-dimethylazulen-3-yl) – 2-cyanopentadiene-2,4-dienoic acid.
- Stilbazulenyl nitrone, the 2nd generation azulene nitrone, can be utilized as a chain splitting antioxidant.
- Near infrared fluorescence quencher based upon BIS azulenyl.
Preparation of Guaiazulene
10 Kg of guacum officinale gum was heated to 130 ° C with 3-4 kg of sulfur. Slowly continue heating to 220 ° C under nitrogen. The water vapor formed is removed with a nitrogen gas stream. The temperature should be above 100 ° C so that water does not fall into the reaction mixture. H2S was obtained by dehydrogenation and removed with steam. Hydrogen sulfide is connected in the alkali trap.
When the H 2S discharge was stopped, the temperature was reduced to 120 ° C and the reaction mixture was distilled in vacuum for 1-20 mm. The distillate is dark blue and contains 6-7 kg of oil and 20% of 7-isopropyl-1,4-dimethyl azulene. It is dissolved in 5-10 volumes of light petroleum, shaken with sodium hydroxide to remove sulfur-containing substances, and washed to neutral. The oil layer is then mixed with 10-15 l of 62% H2SO4 to remove by-products, the oil layer loses its blue color, and the required substances are in the sulfuric acid layer. The last one was shaken with ice and NaOH. As a result, about 7% sodium sulfate solution was obtained. Dilute it to obtain lotion from azulene, extract with 10 L vaseline and distill. 7-isopropyl-1,4-dimethyl azulene was distilled at 167 ° – 168 ° C / 12 mm. The yield is 10-15%.
Reference
- Guaiazulene – WikiPedia
- Guaiazulene – PubChem
Guaiazulene Supplier and Manufacturer
As a guaiazulene supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best guaiazulene raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for guaiazulene and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
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Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Guaiazulene
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