SHANDONG ZHISHANG CHEMICAL CO.LTD.

Factory supply High quality 99% tranexamic acid 1197-18-8

Basic Info

Model No.: LYN- 1197-18-8

Shelf Life: 2 Years

Form:: Powder

CAS: 1197-18-8

Name:: Tranexamic Acid

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 1197-18-8

Port: Shanghai,Tianjin,Qingdao

Product Description

Factory supply High quality 99% tranexamic acid 1197-18-8 

What is Tranexamic Acid?

 

Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin, Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework

for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid

 

Specification of Tranexamic Acid:

 

Items of Test

Limits

Results

Characteristics

White crystalline powder

Complies

Identification

Infrared absorption spectrophotometry 

(2.2.24)IR 

spectrum is in 

concordance with Tranexamic acid CRS

Complies

Solubility

Easy to dissolve in the water and the 

glacial acetic acid, 

difficult to 

dissolve in the acetone and the ethyl

 alcohol

 

Complies

 

PH

7.0–8.0

7.2

Chloride 

≤0.014%

<0.014%

Heavy metals 

≤10ppm

<10ppm

Sulfated ash 

≤0.1%

<0.1%

Related substances (HPLC)

Impurity  A : ≤0.1%

<0.1%

Impurity  B : ≤0.2%

<0.2%

Impurity B : ≤0.2%

All other impurity  : ≤0.2%

<0.2%

 

Assay 

99.0%–101.0%

99.6%

 

Functions of Tranexamic Acid:

 

1.Menstrual bleeding


Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules.Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.

Tranexamic acid is used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.


2.Orthopedic Surgery


Tranexamic acid is used in orthopedic surgery to reduce bloodloss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.


3.Trauma


Tranexamic acid should be considered for use in bleeding trauma patients.

 

Application of Tranexamic Acid:

 

1.Menstrual bleeding of Pure Tranexamic Acid
2.Orthopedic Surgery of Pure Tranexamic Acid
3.Trauma of Pure Tranexamic Acid
4.Dentistry of Pure Tranexamic Acid
5.In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with 
6.In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
7.Whitening effect.Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%

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