Empagliflozin CAS 864070-44-0
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Factory Supply Empagliflozin CAS 864070-44-0 with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Empagliflozin Supplier & Manufacturer
Empagliflozin: The Complete Guide
Empagliflozin for Sale
Basic Info of Empagliflozin
Basic Info
Chemical Properties
Other Info
Basic Info
Chemical Name: | Empagliflozin |
Other Name: | Empagliflozin API; Jardiance; Ou Tangjing; Enpaitang; Shitangda |
CAS: | 864070-44-0 |
EINECS: | 620-176-8 |
Type: | Pharmaceutical raw materials |
Molecular Formula: | C23H27ClO7 |
Molecular Weight: | 450.91 |
Chemical Properties
Boiling point | 665℃ |
density | 1.398 |
Fp | 356℃ |
storage temp. | 2-8°C |
pka | 13.23±0.70(Predicted) |
Other Info
Brand Name: | Zhishang Chemical |
Provide: | Empagliflozin MSDS; Empagliflozin COA |
What is Empagliflozin?
Empagliflozin, the trade name is “Jardiance”, the Chinese trade name is “Ou Tangjing” (Mainland), “Enpaitang” (Taiwan, China) or “Shitangda” (Hong Kong, China), which are brand-new The first-generation SGLT2 inhibitor (kind II sodium-glucose transporter prevention) was accepted by the united state Fda (FDA) in August 2014, and also was approved for advertising in landmass China in September 2017. In combination with diet regimen control and exercise, it is used to deal with type 2 diabetes in adults.
Empagliflozin, a kind 2 sodium sugar cotransporter (SGLT-2, sodium-dependent glucose cotransporter2) inhibitor collectively established by Boehringer Ingelheim and also Eli Lilly. SGLT-2 inhibitor is a new kind of hypoglycemic medication, mainly by inhibiting the expression of SGLT-2, reducing the kidney reabsorption of glucose, enhancing the discharging of sugar in the urine, therefore lowering the degree of plasma glucose, as well as its hypoglycemic result is independent of in beta cell feature as well as insulin resistance.
Empagliflozin decreases the capacity of the kidneys to reuse glucose right into the blood stream and also excrete it in the pee, assisting to considerably minimize blood sugar level degrees, threat of kidney and heart disease, obese and also blood pressure in individuals. Various from various other dental drugs currently utilized for the therapy of kind 2 diabetes, empagliflozin is the very first SGLT2 hypoglycemic medication to complete the cardiovascular prognosis research, as well as it is the only oral hypoglycemic drug that Four-fold effect of protecting the heart, safeguarding the kidney and weight loss.
Empagliflozin Uses
- Individuals with kind 2 diabetes continue to have high blood sugar degrees since their SGLT2 is also energetic. “Engliqing” can decrease the capacity of the kidney to recover glucose right into the blood, and make the sugar excreted out of the body via the pee.
- Restraint of SGLT2 can decrease the amount of sugar reabsorbed right into the blood by proximal kidney tubules, and boost urinary system glucose discharging, warmth loss as well as osmotic diuresis. Therefore, restraint of SGLT2 can considerably boost blood sugar, body weight and high blood pressure.
- Empagliflozin is made use of to improve glycemic control in grownups with type 2 diabetes that have not accomplished ample glycemic control with diet and also workout. It should not be utilized to deal with clients with type 1 diabetes mellitus, people with raised blood or pee ketones (diabetic person ketoacidosis), individuals with severe renal problems, end-stage kidney condition, as well as individuals on dialysis.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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- Phone: +86 176 5311 3209
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If you want to buy empagliflozin, pls contact us to get a free quote.
The Efficacy of Empagliflozin
Sugar control effect
By inhibiting SGLT2 protein in renal tubules, “engliqing” can block the recovery of sugar by the kidney, and the excess sugar will be excreted out of the body through urine, thus helping to manage blood glucose. Therefore, “engliqing” can significantly improve the blood glucose level and make the glycated heme (HbA1c) index reach an ideal level without insulin dependence.- Efficacy in reducing cardiovascular and mortality risk
Different from the oral drugs currently used for the treatment of type 2 diabetes, “engliqing” has become the only oral hypoglycemic drug that has been proved to reduce cardiovascular risk in cardiovascular prognosis research.
According to large international research empa-reg output ® The results showed that in adult patients with type 2 diabetes with high risk of cardiovascular events, the addition of “englitazone” could significantly reduce the cardiovascular risk on the basis of standard treatment. Thus, “engliqing” has become the only oral hypoglycemic drug that has been proved to reduce cardiovascular risk in cardiovascular prognosis research. - Diabetic heart
The average life expectancy of type 2 diabetes patients with high risk of cardiovascular events is shortened by 12 years, and nearly 50% of the death events of type 2 diabetes patients are caused by cardiovascular diseases. In fact, cardiovascular disease has always been the number one killer of patients with type 2 diabetes. This study confirmed that “engliqing” prevented one-third of cardiovascular death events, and it is the only hypoglycemic drug that can reduce cardiovascular risk and cardiovascular death at the same time in cardiovascular prognosis research. - Efficacy in reducing the risk of kidney disease
In the aspect of kidney health “diabetic kidney”, studies have confirmed that “englitazone” can significantly reduce. - Diabetic kidney
Diabetes patients have a much higher chance of suffering from kidney disease than non diabetes people, about half of which are affected by type 2 diabetes. In the late stage, kidney disease is more likely to lead to renal failure, and patients must receive dialysis treatment or kidney transplantation. In addition to being associated with a shorter than average life span, decreased renal function also increases the risk of other diabetes related complications, such as hypoglycemia and cardiovascular disease. - Managing overweight outcomes
Studies have confirmed that “englitazone” can reduce the average weight of 2 to 3 kg and the waist circumference of 2 cm for patients with diabetes.
Reference
- Empagliflozin – WikiPedia
- Empagliflozin – PubChem
Empagliflozin Supplier and Manufacturer
As a empagliflozin supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best empagliflozin raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for empagliflozin and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
FAQ
Shipping
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Empagliflozin
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