Dipotassium Glycyrrhizinate CAS 68797-35-3
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- Appearance: White powder
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Dipotassium Glycyrrhizinate Supplement
Dipotassium Glycyrrhizinate: The Complete Guide
Dipotassium Glycyrrhizinate for Sale
Basic Info of Dipotassium Glycyrrhizinate
Glycyrrhizinate dipotassium; Dipotassium glycyrrhizinate cas 68797-35-3
Food additives; Pharmaceutical raw materials; Sweeteners; Plant extracts; Flavors and fragrances; Cosmetic raw materials
What is Dipotassium Glycyrrhizinate?
Dipotassium Glycyrrhizate (DPG) is an active component drawn out from the origin of the bean licorice (Glycyrrhizauralensis Fisch.). Generally, licorice is primarily separated into 3 classifications: liquorice, expanded fruit liquorice, light fruit liquorice (also known as European liquorice).
Licorice is a perennial herb, belonging to the leguminous household, which is a medical and also edible source. The physiologically energetic components in licorice are mainly triterpenoids, flavonoids as well as glycyrrhizin substances. Amongst them, dipotassium glycyrrhizate is a potassium salt of glycyrrhizate extracted from licorice. It is an all-natural sweetener with anti-inflammatory, anti-viral, liver security as well as cleansing and immune feature enhancement impacts. Compared to sucrose, the sweet taste strength is 80-100 times that of sucrose. As a sweetener, dipotassium glycyrrhizate has the advantages of high sweetness, low cost as well as high safety. According to the preservative criterion, dipotassium glycyrrhizinate can be made use of as a sugar in flour products.
Dipotassium glycyrrhizate is a by-product of glycyrrhizic acid, which has anti-inflammatory, anti-allergic, anti-ulcer, as well as promotion of epithelial cell tissue regeneration. 0.5% dipotassium glycyrrhizate service as well as 0． The anti-inflammatory effect of 1% dexamethasone was similar, but there were no significant negative impacts. Dipotassium glycyrrhizate is a white powder with the attributes of high sweetness, excellent water solubility, low heat energy, low lathering, low hemolysis, security and non-toxicity. At the same time, dipotassium glycyrrhizate has anti-inflammatory, anti-ulcer, antioxidant, antibacterial, wound healing, and reliable scavenging impacts on superoxide ions as well as hydroxyl totally free radicals. Consequently, in the cosmetics market, it can be used in skin lotion, shower gel, blemish lotion, facial mask, etc; in the pharmaceutical industry, it can be used in eye drops, lotion for stomatitis; in the daily chemical market, it can be utilized in toothpaste, mouthwash, shaving cream Wait.
Dipotassium glycyrrhizate has the functions of boosting resistance, hindering inflammation, anti-cancer, anti-virus, anti-stress, triggering the activity of glucocorticoids in the body, and also activating the self-repairing capability of cells. It is usually believed that it relates to its chemical structure. Glycyrrhetinic acid itself It has a similar structure to steroid hormones, so it plays the duty of hormonal agents in the body; as well as its framework is different from steroid hormonal agents, so there are no severe damaging responses as well as adverse effects of hormonal agents. This verdict has been validated by several study organizations.
Dipotassium Glycyrrhizinate Uses
- Scalp Treatment: Eases itchy scalp.
- Oral Care: For the therapy of gingival swelling, dental health as well as tooth defense.
- Skin Care: Lightening – Prevents melanin production and also lightens up complexion. Anti-inflammatory – ideal for the therapy of skin inflammations such as injuries, eczema, burns, and so on, and also take care of delicate, delicate and also short-tempered skin.
- Whitening: Dipotassium glycyrrhizate can inhibit the manufacturing of melanin. The speculative research study chose the back skin of guinea pigs. Under UVB irradiation, the skin pretreated with 0.5% dipotassium glycyrrhizinate was more than the skin whiteness coefficient (L value) of the control group. The consolidated result is amazing. The speculative results show that dipotassium glycyrrhizate has the impact of dramatically inhibiting the manufacturing of melanin. It can be utilized to stop skin coloring and melanin production after sun direct exposure. It is a potential skin whitening representative.
- Anti-inflammatory as well as anti-allergic: Dipotassium glycyrrhizate acts on hormonal agent receptors on cell membranes, impacts ion channels, triggers or prevents enzyme activity, controls compound metabolism and also cholinergic nerve excitability, so as to make capillary wall surfaces and also cell membranes. The permeability of the medicine is decreased, the purpose of lowering inflammatory exudation is attained, and also the formation as well as release of histamine and also various other harmful materials are hindered, so as to have a good anti-inflammatory impact.
When dipotassium glycyrrhizate acts upon LPS-stimulated RAW264.7 cells, it can inhibit the secretion of inflammatory moderator NO as well as inflammatory cytokine IL-6 to varying degrees.
For that reason, dipotassium glycyrrhizate in cosmetics can help in reducing skin redness as well as irritation that are common in different diseases such as rosacea and psoriasis. An additional scientific test has actually revealed that dipotassium glycyrrhizate can efficiently treat atopic dermatitis.
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Application of Dipotassium Glycyrrhizinate
Dipotassium glycyrrhizinate has mineralocorticoid-like effects—sodium retention and potassium excretion and glucocorticoid (Glucocorticoid)-like effects—glucose metabolism, but long-term use has no side effects.
Direct effect: It is generally believed that the chemical structure of glycyrrhetinic acid in dipotassium glycyrrhizinate is similar to that of adrenocortical hormone (Cortin), which affects ion channels and activates or inhibits enzymes by acting on hormone receptors (Receptors) on the cell membrane. Activity, regulate substance metabolism, regulate the excitability of cholinergic nerves. As a result, the permeability of capillary walls and cell membranes is reduced, the inflammatory exudation is reduced, and the formation and release of histamine and other toxic substances are inhibited, thus playing a good anti-inflammatory effect.
Indirect effect: that is, the glycyrrhetic acid in dipotassium glycyrrhizate inhibits the destruction of adrenal cortex hormones in the body, so that its content in the blood increases accordingly, thereby enhancing the body’s resistance to inflammation.
Application of Grass Products in Toothpaste
Glycyrrhizic acid (dipotassium) as well as glycyrrhetic acid products are presently utilized as anti-allergic active ingredients in cosmetics as well as anti-inflammatory and also anti-allergic drugs, and technique has actually proved that the result is very considerable. Similarly, lots of people with oral and gum tissue allergic reactions remain in fantastic demand of a toothpaste that works against allergic reactions and has no adverse responses and reliances. In oral medicine, zinc licorice pills are made use of in mix with vitamin B 2 to deal with canker sores as well as are taken into consideration remarkable. Dental diseases have a high incidence and are progressively concerned by people. As well as we likewise think that prevention is more important than treatment for dental diseases, so a tooth paste that can be anti-inflammatory, anti-allergic, avoid and eliminate numerous oral illness will be welcomed by many people.
In addition, dipotassium glycyrrhizinate can be utilized as a risk-free and also efficient all-natural sugar to replace sodium saccharin in tooth paste, and also its sweet taste is 300 times that of sucrose. Presently, the dental care items on the market consist of Helus periodontal ointment under Lion King, Germany Grant-Gelclair (oral abscess drug), Angileptol dental care remedy under Sigma-Tau Pharmaceuticals, Neo-Stomygen tooth paste under Gruppo Stomygen, and Aventis in Italy. Fluocaril anti-allergic toothpaste, GSK’s periodentyl anti-allergic tooth paste, Japan Youhaotooth oral care toothpaste, domestic popular Yunnan Baiyao’s anti-allergic tooth paste, etc. Suggested dosage of dipotassium glycyrrhizinate in toothpaste 0. 1% to 0.5%.
- Dipotassium glycyrrhizinate – PubChem
- Dou Kangning,Ren Jingli,Wang Zhaocai,Pan Meiling,Yue Xiaoyan.Study on the effect of dipotassium glycyrrhizate on flour quality[J].Food Processing,2016,41(06):21-23.