Dipentene CAS 138-86-3 DL-Limonene
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- Appearance: Yellow liquid
- Assay: 95. 0%min
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Dipentene: The Complete Guide
Index of Dipentene Contents
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Basic Info of Dipentene
(±)-Limonene; LIMONENE; Food grade D-limonene; Dipentene; Dienterpene; Limonene; Limonene; (±)-Limonene, isomer mixture; limonene oil
What is Dipentene?
Limonene, whose scientific name is 1-methyl-4-isopropylcyclohexene, has a molecular formula of C10H16 and a molecular weight of 136.23. It is a monocyclic monoterpene mainly found in orange peel essential oil. It is a colorless to light yellow oily liquid at room temperature, with a specific lemon-like aroma, insoluble in water, and easily soluble in organic solvents such as ethanol.Limonene can be automatically oxidized to oxidized monocyclic monoterpenes under the conditions of light and air contact, such as carvol, limonene-1,2-oxide, etc., with very active chemical properties. Limonene has two configurations, D and L, mainly in the form of D-isomers. D-limonene is mainly found in orange peel oil, grapefruit oil, lemon oil and other essential oils, especially in orange peel oil (more than 90%).
D-limonene can significantly inhibit the activity of Gram-negative and positive bacteria and fungi. Limonene has a wide range of sources, simple extraction and high practical value. A large number of research results show that limonene has good expectorant and asthmatic, anti-oxidant, anti-inflammatory, anti-tumor, dissolving gallstones, and antibacterial effects.
What is the Effect of Dipentene?
Limonene is a plant essential oil, which has obvious inhibitory effect on common rot-causing bacteria that cause meat spoilage. Therefore, it has broad application prospects in the field of antiseptic and fresh-keeping. For example, it can inhibit Staphylococcus aureus, Aspergillus niger, Escherichia coli, etc. Food spoilage. The limonene was emulsified and added to orange juice to explore the preservation effect of limonene. When the addition amount of limonene is above 0.50 g/L, a more obvious effect of preservation is obtained. During the entire experiment and exploration process, the total number of bacteria, pH changes and sensory quality in orange juice were significantly better than the blank control. Strawberry was soaked in the limonene compound solution for 3 min. The test results showed that compared with the blank, each treatment can significantly slow down the decrease of VC, titratable acid and soluble solid content in strawberry fruit, inhibit water loss and decay of strawberry, and can improve Its storability.
Limonene is a safe, non-toxic bacteriostatic substance. A large amount of limonene accumulates on the surface of microorganisms, resulting in a large reduction in the content of unsaturated fatty acids in the membrane, changing the composition of the membrane or destroying the integrity of the membrane, and the proton power can also be reduced. Achieve antibacterial effect. Bacteria, fungi and molds were used as research objects to examine the antibacterial properties of pomelo peel essential oil. Studies have shown that pomelo peel essential oil has a significant inhibitory effect on various microorganisms, and the antibacterial effect gradually increases as the concentration of pomelo peel essential oil increases.
The oxidative damage caused by free radicals is related to the production and development of cancer. The ability to resist oxidative damage is positively related to cancer prevention to a large extent. Essential oil extracts rich in D-limonene have good antioxidant properties and are safe. Literature studies have found that kumquat essential oil rich in D-limonene has good bleaching β-carotene, antioxidant capacity, and DPPH free radical scavenging capacity, which can supplement the body with certain antioxidants and protect the body from oxidative damage.
Inflammation is closely related to cancer. For example, nuclear transcription factor-κβ is an intermediary molecule that links inflammation with cancer. Pro-inflammatory cytokines (such as tumor necrosis factor TNF-α and interleukin IL-6) are involved in cancer. The initial and development stages play an important role. By inhibiting the activity of NF-κβ to interfere with TNF-α or IL-6 signal transmission, it can effectively inhibit the occurrence of cancer. In this process, D-limonene can inhibit the NF-κβ signaling pathway to prevent inflammation and cancer.
It is reported in the literature that limonene can act on the small molecule G protein related to cell growth, inhibit its prenylation and increase the activity and production of potential growth inhibitor TGFβ. Therefore, it is effective against gastric cancer, liver lung cancer, and liver cancer induced by chemical factors. Breast cancer, skin cancer, lymphoma, etc. have obvious preventive and therapeutic effects. D-Limonene can act on the mucosa of the respiratory tract, promote the increase in secretion of the respiratory tract mucosa, weaken the spontaneous activity of bronchial smooth muscles, relieve bronchospasm, thereby benefit the discharge of sputum, achieve the effect of eliminating sputum and saliva, reducing or preventing cough and asthma; or promote The relaxation of the sphincter muscles eliminates the stones, thereby reducing the stimulation of the gallbladder mucosa, alleviating the production of gallstones, and improving the patient’s physique, not only can achieve the purpose of curing, but also prevent the recurrence of stones. Limonene capsules on the market are suitable for the treatment of cholecystitis, cholangitis, gallstones, postoperative biliary syndrome, and indigestion. Studies have found that D-limonene has a better effect on dissolving residual stones and is relatively safe. Cholesterol comes from the biosynthesis of hepatocytes. A mixture containing 97% D-limonene is administered through gallbladder drainage, which may inhibit cholesterol synthesis, effectively clearing bile and dampness, dissolving stones, and conducting long-term investigations on patients after treatment. No postoperative main symptoms.
Source of Dipentene
Dipentene is widely found in natural plants. According to reports, it exists in more than 300 kinds of plant essential oils, and its content ranges from as high as 80-95% (lemon, sweet orange, citrus, grapefruit, bergamot, etc.) to as low as 1% (Palaceae). The three isomers of limonene exist in natural plants. The most common isomer is d-limonene, followed by dl-limonene, and l-limonene is less common in nature. The distribution of these three isomers in natural plants is different
D-Limonene, mainly found in citrus oil, lemon oil, orange oil, white lemon oil, lime oil, grapefruit oil, bergamot oil, elemi resin and other essential oils; in celery oil, dill Oil, fennel oil, yellow wormwood oil and other essential oils are also present, and are widely present in essential oils of plants such as pyrethrum and moss.
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