Dextran CAS 9004-54-0
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Factory Supply Dextran CAS 9004-54-0 with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Dextran Supplier & Manufacturer
Dextran: The Complete Guide
- Item 1: Basic Info
- Item 2: What is Dextran?
- Item 3: Dextran Uses
- Item 4: The Manager has Something to Say
- Item 5: β-Mechanism of Dextran Action on Skin
- Item 6: Four Common Dextrans: Dextran 10 | Dextran 20 | Dextran 40 and Dextran 70
- Item 7: Quality Control of Dextran
- Item 8: Hot Sale Products
- Item 9: Get Dextran Quotation
Dextran for Sale
Basic Info
Basic Info
| Chemical Name: | Dextran |
| Other Name: | Dextran T-3; Dextran40; Dextrane2000 |
| CAS: | 9004-54-0 |
| EINECS: | 232-677-5 |
| Type: | Food additives; Pharmaceutical raw materials; Organic raw materials; Plant Extracts; Sweeteners |
| Molecular Formula: | C17H32O10 |
| Molecular Weight: | 396.42998 |
Chemical Properties
Melting point | 483 °C (decomp) |
alpha | 198 º |
refractive index | 185 ° (C=6, H2O) |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow |
form | Solid |
color | White to slightly off-white |
PH | 2 – 10 |
Water Solubility | Soluble in water, dimethyl sulfoxide, ethylene glycol and glycerol. |
Merck | 14,2948 |
Stability: | Stable. Keep dry. Incompatible with strong oxidizing agents. |
Other Info
| Brand Name: | Zhishang Chemical |
| Provide: | Dextran MSDS; Dextran COA |
What is Dextran?
In the 1940s, Dr. Pillemer initially discovered and also reported that a material in the cell wall surface of yeast can boost resistance. Later on, after additional study by Dr. Diluzio from the University of Tulum, it was located that the substance that boosts immunity in the yeast cell wall is a polysaccharide – β-glucan, and also this material was separated from baker’s yeast.
Glucan is a polysaccharide compound that exists in the mucus produced by some bacteria throughout the growth process. It is split right into α-glucan as well as β-glucan. This compound that can improve immunity was isolated and determined as β-glucan.
β-glucan is commonly discovered in foods such as yeast, mushrooms, oats and also barley, among which β-1,3/ 1,6 exists in yeast and mushroom glucan, while β-1,3/ 1,4 exists in Oat and also barley glucan.
β-glucan is various from usual sugars (such as starch, glycogen, dextrin, etc), the main difference is that the bond connection method is various. The molecular structure of usual sugars is α-1,4-glucoside β-glucan is mostly made up of β-1,3-glycosidic bonds, and has some branched chains of β-1,6-glycosidic bonds. β-glucan has a helical molecular framework because of its special bond link setting and the existence of hydrogen bonds in the molecule. This unique configuration is quickly approved by the immune system.
Dextran Uses
Dental yeast beta-glucans are different from other food active ingredients in that they are not absorbed by the stomach and intestinal tracts, but taken in straight via the small intestine. Macrophages on the mucous cells of the small intestine will certainly be triggered after taking in β-glucan through β-glucan receptors, thus securing as well as reinforcing the body immune system.
β-Glucan can effectively scavenge complimentary radicals in the body, thereby shielding macrophages from totally free radical strikes after radiation, to make sure that these macrophages can remain to operate usually.
β-1, 3-D-glucan has the feature of taking in bile acid as well as advertising excretion of bile acid, promoting the conversion of cholesterol to bile acid, as well as maintaining the intrinsic normal metabolic rate of cholesterol.
β-Glucan has a particular thickness and is challenging to be absorbed in human digestive system body organs, so it can function as nutritional fiber. It can promote digestive peristalsis, absorb harmful compounds in the intestines, promote the activation of helpful microorganisms in the intestines, and soothe acid indigestion caused by weak gastrointestinal system.
β-Glucan can shield as well as fix pancreatic islet β-cells, enhance the level of sensitivity of peripheral tissues to insulin, reduce the demand for insulin, advertise the return of glucose to normal, and have apparent repressive as well as preventative impacts on diabetic issues.
The high viscosity as well as gelling residential or commercial properties of β-glucan boost the barrier function of stomach mucosa as well as inhibit sugar metabolic rate. At the same time, yeast β-glucan can boost associated mold materials in the spleen, control insulin secretion, as well as attain the impact of balancing blood sugar.
Boost the synthesis ability of collagen and elastin in the dermis, decrease the look of skin creases, as well as reveal healthy and balanced and stunning skin.
The skin is a really crucial protection system of the human body, a natural obstacle to isolate the human body from the outside world, as well as likewise has the features of a metabolic and also biochemical immune reaction system. In the epidermis, the skin’s immune system includes cytoplasm, Langerhans cells that control resistance, as well as keratinocytes. Among them, Langerhans cells have been confirmed over the last few years to have a really unique partnership with macrophages in the skin, as well as play an exceptionally crucial function in skin resistance
Under the stratum corneum of the skin, there are lots of immune networks composed of Langerhans cells. Langerhans cells are dendritic cells whose antennae can get to the stratum corneum cells as well as are receptors for β-glucan. β-glucan is a planar helical structure, and also its combination with cell membrane layer receptors causes a collection of stereochemical changes. In addition to its very own sunlight protection as well as decreasing pain and also inflammation, it can also promote the proliferation of Langerhans cells as well as enhance the skin. immunity.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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β-Mechanism of Dextran Action on Skin
Anti-aging effect
β-Dextran is a high-purity cell extract. As a skin activator, it can be recognized and activated by receptors on the membrane of immunoactive cells. β-Dextran increases epidermal growth factor (EGF) in aged and wrinkled skin, which will promote the increase of collagen and elastin in skin, thus improving skin appearance and removing wrinkles.
Ultraviolet radiation can inhibit the Langerhans cells in the skin. If the skin is exposed to the sun for a long time, the number of Langerhans cells will be greatly reduced, the activity will be reduced, and the skin’s defense and immunity will be weakened. and β-In addition to its own sunscreen effect and reducing pain and inflammation, glucan can also promote the proliferation of Langerhans cells and enhance the immune ability of the skin. We found that, β-Dextran can simultaneously promote fibroblast proliferation and collagen synthesis, free radical scavenging ability, resist UV damage, promote immune protection, and moisturize skin in terms of skin anti aging.
Promote wound healing and fade scars
β-Dextran can activate macrophages in the immune system, which produce epidermal growth factor (EGF), thus promoting the production of collagen necessary for wound healing, and angiogenesis factor (AF) can promote the formation of new blood vessels necessary for wound healing. β-Dextran can increase the regeneration ability of damaged skin cells and has the characteristics of helping wound recovery. If used, it contains 0.4% β-The O/W cream of dextran can improve the regeneration rate of the stratum corneum, which is generally about 30% higher than the blank product. Currently, FDA and EU have approved β-Dextran can be used in products for wound and burn treatment.
Anti allergic and anti-inflammatory effects
β-In addition to promoting the proliferation of Langerhans cells and thus enhancing the immune ability of the skin, the clinical research also shows that β-Dextran also has significant anti-inflammatory and anti-allergic activities, and can help skin resist various exogenous mechanical and chemical stimuli. 0.2% concentration β-Dextran has the same anti-inflammatory effect as cosmetics containing 1.0% hydrocortisone. At the same time, β-Dextran can also significantly reduce the effect of skin allergic inflammation caused by stimulating active ingredients such as fruit acid.
Four Common Dextrans: Dextran 10 | Dextran 20 | Dextran 40 and Dextran 70
Dextran 40
Dextran 40 is a high-molecular glucose polymer, which can increase plasma colloid osmotic pressure, absorb extravascular water and expand blood volume. Because of its small molecular weight and rapid excretion, its expansion effect is not long-lasting, but this drug can cover the surface of red blood cells and increase blood volume. The negative charge on the surface makes it difficult for red blood cells to aggregate, and can depolymerize the aggregated red blood cells, thereby reducing blood viscosity and improving microcirculation. Dextran can also wrap around the surface of platelets and cover the damaged vascular intima, thereby inhibiting the adhesion and aggregation of platelets, thereby preventing thrombus formation. It still has an osmotic diuretic effect.
Dextran 40 is mainly used for various shocks, among which the curative effect on hemorrhagic shock is better than dextran 70, because it can improve microcirculation and tissue perfusion in addition to expanding blood volume, and can also be used for trauma, burns and toxic shock. Early prevention of disseminated intravascular coagulation caused by shock. Thrombotic diseases such as cerebral thrombosis, angina pectoris and myocardial infarction, thromboangiitis obliterans, retinal artery and vein thrombosis, skin ischemic ulcer, etc. Limb replantation and vascular surgery can prevent postoperative thrombosis, improve blood circulation, and increase the success rate of replantation.
Dextran 70
The effect of dextran 70 is similar to that of dextran 40, but the blood volume expansion and antithrombotic effects are stronger than the former. It is mainly used to prevent and treat hypovolemic shock and prevent thrombosis and thrombophlebitis after surgery.
Dextran 10 and Dextran 20
Both dextran 10 and dextran 20 belong to small molecule dextran, with an average molecular weight of 10,000-20,000, which can improve microcirculation, increase plasma colloid osmotic pressure, and osmotic diuresis, similar to dextran 40, but improve microcirculation and prevent disseminated intravascular coagulation The effect is stronger than dextran 40, mainly used for acute hemorrhagic shock, trauma and burn shock, acute myocardial infarction, angina pectoris, cerebral thrombosis, cerebral insufficiency, thromboangiitis obliterans, Raynaud’s disease; Increase blood pressure in hypovolemic and hypotensive patients after epidural anesthesia.
Reference
- “dextrans”. The IUPAC Compendium of Chemical Terminology.
- Li Yan, Chen Xuewu. Production and application of dextran[J]. Shanxi Food Industry, 1998 (3): 36-37.’
Dextran Supplier and Manufacturer
As a dextran supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best dextran raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for dextran and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Dextran
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