Delta Damascone CAS 57378-68-4

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Delta Damascone | D-position turketone

CAS 57378-68-4 | C13H20O | 192.3

Appearance: transparent liquid
Purity: 99. 0%min
Stock: In stock
Sample: Available
Zhishang Chemical: Delta Damascone Supplier & Manufacturer

Basic Info of Delta Damascone

CAS No:	57378-68-4
Name:	Delta Damascone
Formula:	C13H20O
Weight:	192.3
EINECS:	260-709-8

Other Names:	D-position turketone
Type:	Additives, Food Additive
Shelf Life:	3 years
Brand Name:	Zhishang Chemical
Place of Origin:	China

What is Delta Damascone?

Delta Damascone is an anemic to light yellow liquid with a blackcurrant-like fruity and rose-like fragrance. It has a boiling point of approximately 263 ° C, a thickness of 0.89 g/cm TWO, and a log P of 4.1. It is insoluble in water yet miscible with alcohols, ethers, esters, and the majority of natural solvents. Its FEMA number is 3622, and it is detailed as an allowed food seasoning with a restriction of 0.02– 0.1 mg/kg. It is extensively used in gummies, beverages, eating gum, and various other food, in addition to in day-to-day chemical items, tobacco products, and perfumes to provide fruity and floral aromas.

Synthesis

Approach 1: At -78 ° C, 1.7 mL (12 mmol) of diisopropylamine and 9.1 mL (14.5 mmol) of 1.6 M n-hexane n-propene option were responded with 1.97 g (12 mmol) of 4-methoxypropene ketone service in 30 mL of tetrahydrofuran to offer 12 mmol LDA. 4-methoxypropene ketone was included utilizing a syringe. The response mix was stirred for 1 hour. The solution was after that treated with 0.52 g (1.4 mmol) of cerium chloride (pre-dried under vacuum cleaner for 2 hours) in 30 mL of THF.
The response mixture was stirred at -78 ° C for half an hour. 2.3 g (12 mmol) of δ-damascone remedy was added dropwise over 10 minutes. The option was mixed for 3 hours. The service was heated to space temperature level. 40 mL of saturated NH4Cl aqueous service was included in the reaction mix.
The reaction combination was extracted with 2x and 50 mL of diethyl ether. Laundry the combined natural phase with water and brine. Dry the response mix on MgSO4. Filter the reaction combination. Evaporate the solvent. Secondarily process the crude product with 20 mL of cool pentane to obtain Delta Damascone.
Approach 2: Utilizing a Solar Light ® XPS200 outfitted with a 150 W xenon arc lamp and AM1.5 filter, irradiate 2 mL of the matching 10 ⁻² m aldol solution in methanol onto a 4 × 4 well polystyrene plate with a 4 mL probe quantity. In all situations, the solution was irradiated under air. The sample was evaluated after a continuous variety of irradiations making use of an Agilent GCMS system to obtain acrylone and Delta Damascone.

Delta Damascone Uses

Delta Damascone is a natural substance with medical value and is commonly made use of as an anticancer medicine in Standard Chinese Medicine. Researches have revealed that Delta Damascone exerts a tumor-suppressive impact by causing apoptosis (configured cell death) in cancer cells. This substance can additionally hinder the task of kinases, which are healthy proteins that play a critical role in cellular division and development.

Researches have revealed that Delta Damascone analogues are effective in dealing with numerous cancers cells, including bladder and lung cancer cells. Moreover, this compound has actually been detected in human pee, suggesting its prospective as a biomarker for cancer cells medical diagnosis and treatment monitoring. To conclude, Delta Damascone, as a natural anticancer medicine, shows terrific application potential.

Organic Intermediate

Delta Damascone is an important intermediate in the preparation of scents and fine chemicals, frequently utilized for light conversions such as thiolation/heterocyclization. The response problems are favorable, making it appropriate for scale-up production. As an example: Delta Damascone (2.7 mmol) is added to DMF (15 mL) with potassium thioacetate (5.54 mmol).

The mix is mixed at 80 ° C for 1 day to develop a black suspension. The mixture is after that cooled down to room temperature level. 32% (0.54 mL) of hydrochloric acid aqueous remedy is included in the mixture. Continue mixing at area temperature for 1 hour, after that filter to obtain the product.

Isomerization

The “climbed ketone” family members includes a number of various molecules, almost all with aromas of steamed apple, blackcurrant, and Damask increased important oil. 8-Damascone has a similar scent to damasscone, which has a slightly woody note.

Delta Damascone and γ-damascone, on the other hand, have a lot more extreme rose and coniferous notes, specifically. α-Violet and ẞ-Violetone are positional isomers of the damasscone particle because their ketone teams are located on various carbon atoms, and their methyl groups are also in various placements. Regardless of this, their aromas are quite distinctive, as violetone substances are more reminiscent of violet blossoms.

Specifications & Packaging

Specification

Product Nature

Specification

Product Nature

Product Packaging

Application of Delta Damascone

Delta Damascone is a flexible compound, renowned for its one-of-a-kind floral-fruity scent, and is a crucial basic material in the scent and flavor industry. This substance is generally utilized in the solution of fragrances, cosmetics, and personal treatment products, where its fascinating fragrance improves the overall sensory experience. Furthermore, Delta Damascone is additionally a vital active ingredient in flavors, imparting abundant and luring tastes to a variety of foods. Its stability and compatibility with various other scent ingredients make it suitable for developing lasting fragrances in a range of applications.

Researchers and sector experts alike value Delta Damascone’s possibility in developing novel fragrance formulations and boosting product appeal. Its distinct structure enables a rich series of fragrance notes, appropriate for both high-end perfumes and daily consumer items.

Furthermore, Delta Damascone blends perfectly with various other aromatic compounds, making it possible for formulators to flexibly create bespoke fragrances to fulfill certain market needs. As a result of its tested efficiency and broad applicability, Delta Damascone has come to be a crucial active ingredient for those looking for technology in the scent and flavor sector.

Delta Damascone is widely made use of in research study concentrated on:

Fragrance Industry: Delta Damascone is regularly utilized as a crucial active ingredient in fragrances and fragrance products, providing abundant flower notes and enhancing the overall scent.
Flavoring Representatives: This compound is also made use of in the food sector to convey pleasurable preferences and fragrances to a range of foods, making it a prominent selection for seasoning applications.
Cosmetics: In the cosmetics area, Delta Damascone is utilized in the formula of skincare and beauty products to assist improve their scent and enhance the individual experience.
Aromatherapy: Its fragrant residential properties make it appropriate for essential oils and aromatherapy items, promoting relaxation and health.
Research Study Applications: Delta Damascone is being researched for its possible health and wellness advantages and bioactivity, making it appropriate in fields such as pharmacology and biochemistry and biology.

References

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Delta Damascone Supplier and Manufacturer

As a Delta Damascone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best Delta Damascone raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for Delta Damascone and related products, please contact our service staff Zhishang Chemical directly, and we will provide you with high-quality products at the best price.

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Boiling point	253 °C
Density	0.890±0.06 g/cm3
Refractive index	n20/D 1.490-1.500
Odor	10.00% dipropylene glycol solution. Fruity
form	liquid
color	transparent
Fragrance type	floral