
Clindamycin Phosphate CAS 24729-96-2



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- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Clindamycin Phosphate Supplier & Manufacturer
Clindamycin Phosphate: The Complete Guide
- Item 1: Basic Info of Clindamycin Phosphate
- Item 2: What is Clindamycin Phosphate?
- Item 3: Clindamycin Phosphate Uses
- Item 4: The Manager has Something to Say
- Item 5: Synthesis of Clindamycin Phosphate
- Item 6: Reference
- Item 7: Quality Control of Clindamycin Phosphate
- Item 8: Hot Sale Products
- Item 9: Get Clindamycin Phosphate Quotation
Clindamycin Phosphate for Sale
Basic Info of Clindamycin Phosphate
Chemical Name: | Clindamycin Phosphate |
Other Name: | (2R,3R,4S,5R,6R)-6-((1S,2S)-2-Chloro-1-((2S,4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4,5-dihydroxy-2-(methylthio)tetrahydro-2H-pyran-3-yl dihydrogen phosphate |
CAS: | 24729-96-2 |
EINECS: | 246-433-0 |
Type: | Food additives; Pharmaceutical raw materials |
Molecular Formula: | C18H34ClN2O8PS |
Molecular Weight: | 504.96 |
Melting point | 114 °C |
Boiling point | 159°C |
density | 1.41±0.1 g/cm3(Predicted) |
refractive index | 122 ° (C=1, H2O) |
storage temp. | Sealed in dry,2-8°C |
solubility | DMSO: soluble224mg/mL at 25°C |
form | solid |
pka | pKa 0.964±0.06 (H2O t=21) (Uncertain);6.06 ±0.06 (I=0.008)(H2O t=21) (Uncertain) |
color | White |
Water Solubility | Freely soluble in water |
Stability: | Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins. |
Brand Name: | Zhishang Chemical |
Provide: | Clindamycin Phosphate MSDS; Clindamycin Phosphate COA |
What is Clindamycin Phosphate?
Clindamycin phosphate, trade name Cleocinphosphate, chemical name 6-(1-methyl-trans-1-propyl-L-2-pyrrolidinecarboxamido)-1-thio-7( S)-Chloro-6,7,8-trideoxy-L-threo-α-D-galactopyranoside-2-dihydrogen phosphate, a semi-synthetic derivative of clindamycin, It rapidly hydrolyzes clindamycin in vivo and exhibits pharmacological activity.
Clindamycin phosphate is a chemical semi-synthetic derivative of clindamycin. It is a white or off-white crystalline powder at room temperature, odorless, bitter in taste and hygroscopic. It has no antibacterial activity in vitro, and can be rapidly hydrolyzed into clindamycin after entering the body to exert its pharmacological effect.
Its mechanism of action, antibacterial spectrum, indications, and therapeutic effects are the same as those of clindamycin, but its lipid solubility and permeability are better than those of clindamycin. It can be administered orally or intramuscularly and intravenously, mainly in the liver. Metabolized, excreted in bile and feces, partially excreted in urine. Compared with lincomycin, clindamycin phosphate has 4 to 8 times stronger antibacterial effect, good absorption, high bone tissue concentration, and strong antibacterial activity against Gram-positive cocci and anaerobic bacteria. Its antibacterial spectrum is: Gram-positive cocci include penicillin G-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus (except Streptococcus phosphate), Streptococcus pneumoniae, Micrococcus, etc.; Gram-positive bacilli include Clostridium spp. Bacillus, diphtheria, etc.; anaerobic bacteria include Clostridium, Bacteroides, Clostridium, Propionibacterium, Eubacterium, anaerobic coccus, etc.
Clinically, clindamycin phosphate is mainly used to treat tonsillitis, suppurative otitis media, sinusitis, acute bronchitis, acute exacerbation of chronic bronchitis, pneumonia, lung abscess, bronchiectasis complicated infection and skin and soft tissue infection, such as furuncle, carbuncle , abscess, cellulitis, wound infection, burn infection, postoperative infection, etc., as well as acute urethritis, acute pyelonephritis, prostatitis, etc. of the urinary system, also used for osteomyelitis, sepsis, peritonitis, oral infection, etc.
Clindamycin Phosphate Uses
Clindamycin phosphate is hydrolyzed right into clindamycin with antibacterial activity after getting in the body. It has significant antibacterial effect, as well as has no cross-allergic response with penicillin as well as cephalosporin antibiotics. It can be utilized for those allergic to penicillin.
Clindamycin blocks protein synthesis by binding to 23S ribosomal subunits. Clindamycin has been proved to have neuromuscular blocking properties, which can enhance the effects of other neuromuscular blockers.
Clindamycin Phosphate Shot is a colorless or somewhat yellow clear liquid. Generally utilized for the complying with various contagious illness caused by Gram-positive germs:
- Skin and soft cells infections: boils, carbuncles, abscesses, cellulitis, wounds, burns and also post-operative infections.
- Urinary system infection: severe urethritis, acute pyelonephritis, prostatitis, and so on
- Others: osteomyelitis, blood poisoning, peritonitis as well as oral infection.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
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If you want to buy clindamycin phosphate, pls contact us to get a free quote.
Synthesis of Clindamycin Phosphate
The synthesis scheme of choline phosphate clindamycin is shown in the figure. The synthesis of CH CP is as follows. Weigh clindamycin phosphate (1.00 g, 1.98 mmol), add 10 ml of distilled water, and stir until transparent. Then gradually add choline (48-50% aqueous solution, 0.96g, 3.96mmol). Under closed conditions, the reactant solution was stirred at 25 ℃ for 24 hours, and then concentrated at 40 ℃. After vacuum drying at 35 ℃ overnight, a yellowish viscous choline phosphate clindamycin liquid was obtained with a yield of 1.06 g (75.4%).
Reference
- Clindamycin phosphate – PubChem
- “Synthesis of a chiral ionic liquid, cholinium-clindamycin phosphate,”.
Clindamycin Phosphate Supplier and Manufacturer
As a clindamycin phosphate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best clindamycin phosphate raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for clindamycin phosphate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Clindamycin Phosphate

