CAS NO 401-78-5 3-Bromobenzotrifluoride

Production methods 1. Trifluoromethylbenzene direct bromination The method yield 80%. Raw materials consumption fixed: trifluoromethyl benzene (≥ 98%) 686kg / t, bromine 1142kg / t, iron 200kg / t. 2. Inter-aminotrifluorotoluene diazotization, replaced derived. Amine trifluoromethanesulfonic acid is slowly added to the hydrobromic acid with stirring at a temperature not exceeding 50 ° C. Cooling, adding sodium nitrite solution, the temperature was controlled below 10 ℃, to the end of diazotization. The diazo solution is added to boiled cuprous bromide and hydrobromic acid solution, and steam distillation begins, the organic matter with the steam distilled. Distillate stratification, take the organic layer, add concentrated sulfuric acid washing, reuse water, dilute alkaline solution, washed with water until neutral. Dehydration of anhydrous calcium chloride reservoir, filtration, vacuum distillation, collecting 73-74.5 ° C (6.0kPa) fraction to obtain m-Bromobenzotrifluoride. Use for organic synthesis. Mainly used in the production of pesticides, pharmaceuticals, synthetic fenfluramine and other drugs.

Product expansion
1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the raw material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories. The former is a class of cosmetics in the main raw materials, cosmetics in the possession of a large proportion of the cosmetics play a major role in the role of the material. The latter is the formation of cosmetics, stability or to give color, smell and other characteristics of the role of these substances in the cosmetic formula is not used, but it is extremely important. Cosmetics are natural, synthetic or extracted from the role of different substances as raw materials, by heating, mixing and emulsification and other production processes processed from the chemical mixture.
2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.It is one substance or mixture during the medicine making period, it can not be taken directly by patients.
3> Fragrance And Spices: Spice is a substance that can be scented by smelling or scented by taste, and is the raw material for the preparation of the fragrance. Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.
4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, pesticides, pharmaceuticals, resins, additives, and other intermediates.
5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion, usually in resin, or oil, or emulsion is given priority to, add or not add pigment, filler, add the corresponding additives, organic solvents or water preparation of viscous liquid.