Model No.: CAS NO 109-65-9
Type: Pharmaceutical Intermediates
MP:: -112 °C
Density:: 1.276 G/mL At 25 °C(lit.)
Bp:: 100-104 °C(lit.)
FP:: 23 °C
Refractive Index:: N20/D 1.439(lit.)
Packaging: in 25kg drum
Productivity: 10000kg per month
Place of Origin: Shandong, China (Mainland)
Supply Ability: in stock
Certificate: ISO CE
HS Code: 109-65-9
1. By the presence of n-butanol and bromine in the presence of red phosphorus derived; or n-butanol in the presence of sulfuric acid and hydrobromic acid derived. N-butanol and hydrobromic acid were mixed, added dropwise sulfuric acid, heated to reflux for 1.5h, distilled to give crude bromobutane, washed with water to pH 6-7, dehydrated with anhydrous calcium chloride derived.
2. Method: In 250mL reaction flask was added 20mL water, carefully added 20mL of concentrated sulfuric acid. Mix well and cool to room temperature. Add n-butanol sequentially
(2) 15g (0.2mol), finely ground sodium bromide 25g (0.24mol). Add 2 zeolites and install a reflux condenser (top air tube to hydrogen bromide absorption bottle). Heated to reflux reaction 1.5h, shaking the reaction bottle constantly during the period. After the cold into the distillation unit, heated distillation, until the distillate turned cloudy from turbidity to n-bromobutane crude. The crude product was washed with water, the organic layer was separated, washed with 10 mL of concentrated sulfuric acid, washed with water, saturated sodium bicarbonate and water successively, dried over anhydrous sodium sulfate and distilled to collect 99-103C fractions to obtain ortho-bromobutane. .
Uses: Used as alkylating agents, solvents, rare elements extractant and for organic synthesis.
1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the raw material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories. The former is a class of cosmetics in the main raw materials, cosmetics in the possession of a large proportion of the cosmetics play a major role in the role of the material. The latter is the formation of cosmetics, stability or to give color, smell and other characteristics of the role of these substances in the cosmetic formula is not used, but it is extremely important. Cosmetics are natural, synthetic or extracted from the role of different substances as raw materials, by heating, mixing and emulsification and other production processes processed from the chemical mixture.
2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.It is one substance or mixture during the medicine making period, it can not be taken directly by patients.
3> Fragrance And Spices: Spice is a substance that can be scented by smelling or scented by taste, and is the raw material for the preparation of the fragrance. Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.
4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, pesticides, pharmaceuticals, resins, additives, and other intermediates.
5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion, usually in resin, or oil, or emulsion is given priority to, add or not add pigment, filler, add the corresponding additives, organic solvents or water preparation of viscous liquid.