Bottom Price High Quality Posaconazole 171228-49-2

Basic Info

Model No.: LYN- 171228-49-2

Shelf Life: 2 Years

Form:: Powder

CoA: Available

Sample: Free

CAS: 171228-49-2

Name:: Posaconazole

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

Port: Shanghai,Tianjin,Qingdao

Product Description

Bottom Price High Quality Posaconazole 171228-49-2

 Introduction:

 Name:Posaconazole                

 

CAS: 171228-49-2                

 

MF:C37H42F2N8O4                                

 

Purity:more than 99%                 

 

Posaconazole (SCH-56592)

 

Appearance:White or off-white crystalline powder       

 

Assay(Titration):98.0 to 102.0%

 Specification

 

Item

Specifications 

Result

Appearance

White or off-white powder

White powder

Specific rotation

-28°~-34°

-32°

Indentification

IR:Sample spectrum corresponds to that of standard spectrum

Conform

HPLC: Retention time of sample comparable

 with retention time of standard

Conform

Water

≤ 2.0%

1.2%

Related substances (1)

PO-R1 ≤0.10%

ND

PO-R2 ≤0.10%

ND

PO-R3 ≤0.10%

ND

PO-R4 ≤0.10%

ND

PO-D3&PO-D5 ≤0.10%

0.08%

PO-D7&PO-D10 ≤0.10%

ND

Any single unknown impurity ≤0.10% 

0.04%

Total impurities ≤1.0%

0.1%

Related substances (2)

PO-E ≤0.10%

ND

PO-D1 ≤0.10%

0.01%

PO-R5 ≤0.10%

ND

Residual solvents

Methanol ≤3000ppm

22ppm

Enthanol ≤5000ppm

4744ppm

Dichloromethane ≤600ppm

115ppm

Ter-Butanol ≤200ppm

ND

Ter-butyl methyl ether ≤5000ppm

13ppm

Tetrahydrofuran ≤720ppm

7ppm

Triethylamine ≤100ppm

1ppm

Toluene ≤890ppm

31ppm

N,N-Dimethylformamide ≤880ppm

2ppm

Residue on ignition

≤0.1%

0.04%

Heavy Metal

≤20ppm

Conform

Assay

98.0%~102.0% (On anhydrous and solvents free basis)

100.6%

Conclusion

The product conforms to the above specification

Storage condition

Store at a temperature not exceeding 30℃

 

 

 

  Function:

 

Posaconazole is an antifungal agent structurally related to itraconazole. It is a drug derived from itraconzaole through the replacement of the chlorine substituents with flourine in the phenyl ring, as well as hydroxylation of the triazolone side chain. These modifications enhance the potency and spectrum of activity of the drug. Posaconazole can be either fungicial or fungistatic in action.

 

Package:

 

0.5kgs/Al-foil bag                       1.0kgs/Al-foil bag                                   2.0kgs/Al-foil bag

 

5.0 kgs/Al-foil bag                     25.0 kgs/drum                                      or upon customers’ request.

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