β Nicotinamide Mononucleotide NMN CAS 1094-61-7

β-nicotinamide mononucleotide-nicotinamide mononucleotide, also called β-nicotinamide mononucleotide (NMN), is a synthetic substrate of coenzyme I, and NMN is also used in anti-aging research. Keio University in Japan and Washington University in the United States are conducting human clinical trials on the anti-aging effects and safety of β-NMN. Studies have shown that β-NMN can also regulate the secretion of insulin and affect the expression level of mRNA. β-NMN has a broad application prospect in the field of medical treatment. β-nicotinamide mononucleotide is the product of extracellular nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It improves glucose tolerance by restoring HFD-induced NAD+ levels in T2D mice. It also enhances liver insulin sensitivity and restores gene expression related to oxidative stress, inflammation, and circadian rhythm in part through SIRT1 activation.

Nicotinamide mononucleotide (NMN for short) is a substance inherent in the human body, and it is also rich in some fruits and vegetables, including broccoli, cabbage, etc.