Model No.: CAS NO 626-39-1
Type: Pharmaceutical Intermediates
Appearance:: White Powder
Density: 2.281 G/cm3
MP: 117-121 °C(lit.)
BP: 271 °C(lit.)
Packaging: 25 kg/net bag on pallets or as your requirement
Productivity: 10000kg per month
Place of Origin: Shandong, China (Mainland)
Supply Ability: in stock
Certificate: ISO CE
HS Code: 626-39-1
Best selling Tribromobenzene CAS 626-39-1
1,3,5-Tribromobenzene, is a reagent that can be used in the preparation of different inhibitors. It is also a substituted Bromobenzene, a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.
Melting point 117-121 °C (lit.)
Boiling point 271 °C (lit.)
Flash point 271°C
Storage Room temperature.
Color Almost white to orange-brown
Water Soluble in hot ethanol and acetic acid. Insoluble in water.
CAS Database 626-39-1 (CAS DataBase Reference)
1. The dried bromine was added dropwise to a mixture of boiling fluorobenzene and pyridine, and the hydrogen bromide generated by the reaction was absorbed by water. Then continue heating for 2h. After cooling, sodium hydroxide solution was added and extracted with ether. The extract was dried over anhydrous potassium carbonate and fractionated. The 75-90°C fraction is unreacted fluorobenzene and the 148-154°C fraction is p-bromofluorobenzene. The yield is about 49%.production method
In a 15L round bottom flask, place 100 g (1.1 mol) of aniline, 1 L of water, and 100 mL (1
2.mol) concentrated hydrochloric acid. When the aniline is dissolved, 5 L of water is added and the flask is cooled in an ice bath. Then 577 g (185 mL, 3.6 mol) of bromine was slowly fed until the solution had a significant yellow color, which took about 34 h and the reaction was complete. The tribromoaniline was eluted with Brinell. The hydrobromic acid was thoroughly washed off with water and sucked dry. In a 5 L flask equipped with a reflux condenser, wet tribromoaniline, 2.1 L of 95% ethanol, and 525 mL of benzene were placed. The flask was placed on a steam bath and heated to dissolve the tribromoaniline. 140 mL of concentrated sulfuric acid was added to the solution, and then 140 g (2.03 mol) of powdery sodium nitrite was added while maintaining the reaction under normal conditions. When the reaction is complete, the solution is heated and boiled, and this state is maintained until no more gas escapes, and then placed in a warm place for 3 hours. After the mixture was cooled, it was filtered and then a solution of 150 mL of concentrated sulfuric acid and 1.5 L of water was added to the solid. When the excess sodium nitrite has been decomposed, it is filtered, the solid is washed with water and then washed with a small amount of ethanol. Crude dry 1,3,5-tribromobenzene is red-brown, melting point 112~116°C, yield 250~260g, yield 74%~7
It is an important organic synthesis intermediate.
Q1. Are you a manufacturer
Answer: Yes, we have our own factory called [ZhiShang Industry Group “, we export by ShandongZhishangchemical Co., Ltd.
Q2. Do you have GMP or DMF
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment
Answer: Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well
Q5. When will you deliver the goods
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping.
You also can choose your own shipping forwarder.
Q7. When will we receive the goods
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions.
Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.
why choose us ?
1.Full experience of large numbers containers loading in Chinese sea port.
2.Fast shipment by reputed shipping line.
3.Packing with pallet as buyer’s special request.
4.Best service after shipment with e mail.
5.Cargoes together with container sales service available.
6.Full experience for Canada & Japan export.
7.Cargoes photo before and after loading into container.
8.Raw materials from Chinese origin.
1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the raw material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories. The former is a class of cosmetics in the main raw materials, cosmetics in the possession of a large proportion of the cosmetics play a major role in the role of the material. The latter is the formation of cosmetics, stability or to give color, smell and other characteristics of the role of these substances in the cosmetic formula is not used, but it is extremely important. Cosmetics are natural, synthetic or extracted from the role of different substances as raw materials, by heating, mixing and emulsification and other production processes processed from the chemical mixture.
2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.It is one substance or mixture during the medicine making period uut it can not be taken directly by patients.
3> Fragrance And Spices: Spice is a substance that can be scented by smelling or scented by taste, and is the raw material for the preparation of the fragrance. Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.
4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, pesticides, pharmaceuticals, resins, additives, and other intermediates.
5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion, usually in resin, or oil, or emulsion is given priority to, add or not add pigment, filler, add the corresponding additives, organic solvents or water preparation of viscous liquid.