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Benzimidazole CAS 51-17-2

Factory Supply Benzimidazole CAS 51-17-2 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Benzimidazole Supplier & Manufacturer

Basic Info

What is Benzimidazole?

1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and also a polycyclic heteroaromatic hydrocarbon. It is the conjugate acid of benzimidazolides. It is a tautomer of 4H-benzimidazole, 2H-benzimidazole as well as 3aH-benzimidazole.

Benzimidazole substances are commonly utilized in the fields of chemicals, medicine, as well as materials. Furthermore, its unique imidazole structure inhabits an important setting in various drug research study, specifically in the growth of PARP preventions.

The setting of activity of benzimidazoles has actually been explained in numerous comprehensive reviews (1,32,33). The primary setting of activity of benzimidazoles has actually been recognized as binding especially to the β-subunit of fungal tubulin, thereby disrupting microtubule setting up. Microtubules, a significant component of the fungal cytoskeleton, are involved in meiosis and mitosis, both of which are blocked in the presence of benzimidazoles.

Benzimidazole Uses

  1. Benzimidazole is used for synthesizing drugs such as vitamin B12 and preparing polymer compounds.
  2. Benzimidazole can be used as an intermediate for the preparation of fungicides such as imidazole and prochloraz.
  3. A template compound commonly used for the electropolymerization and electrodeposition of pyrrole on pencil graphite electrodes to prepare molecularly imprinted polymers, as well as for the preparation of benzimidazole surfactant 1-hexadecyl-1H-benzimidazole.
  4. Benzimidazole is the basic raw material for manufacturing albendazole, mebendazole, trichlorobenzazole and other insect repellents, as well as pantoprazole, rabeprazole, lansoprazole and omeprazole and other anti ulcer drugs. It is used to prepare benzoimidazole linked polymers (BILP) derived from pyrene, and due to its porous material, renewability, and adsorbent selection parameters, it can be used for selective carbon dioxide separation applications.

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Application of Benzimidazole

Benzimidazole by-products are among the most typically utilized little molecule drug cycles noted by the United States Fda. Lots of medicines belong to the benzimidazole course of compounds. As an example:

  • Angiotensin II receptor blockers such as azilsartan, candesartan and telmisartan.
  • Insect repellents such as albendazole, cichlobenzazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxfendazole, trichlorobenzazole, as well as thiabendazole.
  • Antihistamines, such as astemizole, bilastine, crimidazole, emedastine, mizolastine, and also oxatomide.
  • Benzimidazole fungicides, such as benzimidazole, carbendazim, thiabendazole, thiabendazole, etc.
  • Benzimidazole opioid medications, such as Bezidomide, Bromine, Chloronitrogenase, Etotriazide, Etotriazide, Etotriazepine, Etotriapine, Isonicotinite, Metornitrate, and also Metornitrate.
  • Proton pump preventions such as dextran lansoprazole, esomeprazole, eprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole, and titoprazole.
  • Typical antipsychotic medicines such as benperidol, clopidogrel, droperidol, neflumozide, oxiperamide, as well as pimozide.
  • Other popular drugs containing benzimidazole groups include abemaciciclib, bendamustine, dabigatran, daridorexant, and glasdegib.

In the manufacturing of published motherboard, benzimidazole can be utilized as a natural solderability protector. A number of dyes are stemmed from benzimidazole.

Reference

  1. Benzimidazole – WikiPedia
  2. H. A. Barker; R. D. Smyth; H. Weissbach; J. I. Toohey; J. N. Ladd & B. E. Volcani (February 1, 1960). “Isolation and Properties of Crystalline Cobamide Coenzymes Containing Benzimidazole or 5,6-Dimethylbenzimidazole”Journal of Biological Chemistry

Benzimidazole Supplier and Manufacturer

As a benzimidazole supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best benzimidazole raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for benzimidazole and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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