Azithromycin Powder CAS 83905-01-5
Factory Supply Azithromycin Powder CAS 83905-01-5 with Best Price
- Appearance: White powder
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Azithromycin Suppiler&Manufacturer
Azithromycin Powder: The Complete Guide
Azithromycin for Sale
Basic Info of Azithromycin Powder
Azithromycin Powder; Azithromycin 500mg; Azithromycin bnf
Pharmaceutical intermediates; Pharmaceutical raw materials; Organic raw materials
What is Azithromycin Powder?
Azithromycin powder is an antibiotic coming from the macrolide, chemical name: 13- [( 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-nucleo-hexopyranose base)oxy] -2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11- [[ 3,4,6-trideoxy- 3-(Dimethylamino)-β-D-wood-hexpyranosyl] oxy] -1-oxa-6-azacyclopentadecan-15-one. It is a white crystalline powder or granule with a somewhat astringent taste, practically no bitterness as well as no hygroscopicity. This product is conveniently soluble in methanol, ethanol and acetone, easily soluble in acidic water, as well as almost insoluble in neutral and alkaline water.
Azithromycin powder is a commonly made use of antibiotic medication, which has the advantages of broad antibacterial range, much less irritability to the stomach system, and also fast oral absorption. It is used by adults and children alike. Azithromycin has less side effects than cephalosporins, and also is currently the most typically used antibiotic medicine for the treatment of microbial infection-related illness in health centers in my nation. This drug is a second-generation semi-synthetic by-product of macrolides. Unlike erythromycin, it inserts a methyl-substituted nitrogen at the 9a setting of the erythromycin lactone ring, causing a 15-membered macrolide.
The system of activity of azithromycin powder resembles that of erythromycin. It binds to the 50S subunit of the ribosome of sensitive bacteria and hinders RNA-dependent protein synthesis to exert an antibacterial impact, retaining the anti-bacterial spectrum of regular erythromycin. The task against chlamydia is similar to that of erythromycin. Compared to erythromycin, the antibacterial task against Gram-negative bacteria has been substantially boosted. The antibacterial activity versus influenza bacillus and also Neisseria gonorrhoeae is more than 4 times more powerful than that of erythromycin, as well as the antibacterial activity against Legionella has to do with 2 times more powerful. The antibacterial activity against Enterobacteriaceae was also dramatically stronger than that of erythromycin.
Azithromycin powder reversibly binds to the 50S ribosomal subunit of 70S ribosome of sensitive bacteria, thus hindering the translocation step of protein synthesis. The freshly synthesized peptide tRNA particles relocate from the receptor website on the ribosome to the peptide (benefactor) website, therefore hindering RNA dependent healthy protein synthesis, causing cell growth restraint and cell death.
Macrolide anti-biotics, 15 membered nitrogen heterocycles, have comparable anti-bacterial device to erythromycin, but have a broader antibacterial spectrum. The antibacterial activity versus gram-positive microorganisms is more powerful, as well as against gram-negative germs such as Haemophilus flus, Salmonella, Escherichia coli, Shigella, etc. It is steady to acid and also has good tolerance. It has great healing result on respiratory system infection, skin and also soft cells infection, sexually transmitted diseases triggered by sensitive strains.
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Application of Azithromycin Powder
This item is suitable for the treatment of the complying with signs of infection caused by delicate germs:
- For intense pharyngitis as well as acute tonsillitis caused by Streptococcus pyogenes.
- Sinusitis, severe otitis media, intense respiratory disease, acute exacerbation of persistent bronchitis brought on by delicate bacteria.
- For pneumonia caused by Streptococcus pneumoniae, Bacillus influenzae as well as Mycoplasma pneumoniae.
- For urethritis, cervicitis as well as pelvic inflammatory disease brought on by chlamydia and non-multidrug-resistant Neisseria gonorrhoeae, and simple genital infection triggered by non-multidrug-resistant gonococcus (requirement to exclude the co-infection of Treponema pallidum).
- For skin and also soft tissue infections triggered by sensitive bacteria.
What is the difference between azithromycin and erythromycin?
Erythromycin and azithromycin belong to the same class of drugs and have the same mechanism of action and action characteristics, but there are also obvious differences, mainly in:
Erythromycin has weak antibacterial activity and a narrow antibacterial spectrum. It is only effective against gram-positive bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes, as well as atypical pathogens such as Mycoplasma pneumoniae, Chlamydia, and Legionella. It has little effect on gram-negative bacteria and anaerobic bacteria, and bacteria are prone to resistance to it.
Azithromycin has been structurally modified to enhance its antibacterial activity against Gram-positive bacteria and atypical pathogenic bacteria, as well as against Gram-negative bacteria such as Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, Klebsiella pneumoniae, and fragile Anaerobic bacteria such as Bacteroides have strong antibacterial activity and are not easy to develop drug resistance.
Azithromycin Powder Suppliers and Manufacturers
As a azithromycin powder supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best azithromycin raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have demand for azithromycin powder and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.